Ubiquitin hydrolase UCH-L1 destabilizes mTOR complex 1 by antagonizing DDB1-CUL4-mediated ubiquitination of raptor.
about
A genome-wide siRNA screen in mammalian cells for regulators of S6 phosphorylationUbiquitin carboxyl-terminal esterase L1 (UCHL1) is associated with stem-like cancer cell functions in pediatric high-grade gliomaUSP9X deubiquitylating enzyme maintains RAPTOR protein levels, mTORC1 signalling and proliferation in neural progenitors.Ubiquitin carboxyl terminal hydrolyase L1-suppressed autophagic degradation of p21WAF1/Cip1 as a novel feedback mechanism in the control of cardiac fibroblast proliferationUCH-LI acts as a novel prognostic biomarker in gastric cardiac adenocarcinoma.UCHL1 is a biomarker of aggressive multiple myeloma required for disease progressionUCH-L1 is induced in germinal center B cells and identifies patients with aggressive germinal center diffuse large B-cell lymphoma.Ubiquitin pathways in neurodegenerative disease.Targeting childhood, adolescent and young adult non-Hodgkin lymphoma: therapeutic horizons.Proteomic Analysis After Status Epilepticus Identifies UCHL1 as Protective Against Hippocampal Injury.mTOR Signaling in Parkinson's Disease.MNK Controls mTORC1:Substrate Association through Regulation of TELO2 Binding with mTORC1.Life and death in the trash heap: The ubiquitin proteasome pathway and UCHL1 in brain aging, neurodegenerative disease and cerebral Ischemia.Mammalian target of rapamycin (mTOR) as a potential therapeutic target in various diseases."Free" Raptor - a novel regulator of metabolism.TRAF2 and OTUD7B govern a ubiquitin-dependent switch that regulates mTORC2 signalling.Gene regulation of mammalian long non-coding RNA.UCH-L1 promotes invasion of breast cancer cells through activating Akt signaling pathway.Fatty Acid Synthase induced S6Kinase facilitates USP11-eIF4B complex formation for sustained oncogenic translation in DLBCL.MNK inversely regulates TELO2 vs. DEPTOR to control mTORC1 signaling.
P2860
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P2860
Ubiquitin hydrolase UCH-L1 destabilizes mTOR complex 1 by antagonizing DDB1-CUL4-mediated ubiquitination of raptor.
description
2013 nî lūn-bûn
@nan
2013年の論文
@ja
2013年学术文章
@wuu
2013年学术文章
@zh-cn
2013年学术文章
@zh-hans
2013年学术文章
@zh-my
2013年学术文章
@zh-sg
2013年學術文章
@yue
2013年學術文章
@zh
2013年學術文章
@zh-hant
name
Ubiquitin hydrolase UCH-L1 des ...... ated ubiquitination of raptor.
@en
Ubiquitin hydrolase UCH-L1 des ...... ated ubiquitination of raptor.
@nl
type
label
Ubiquitin hydrolase UCH-L1 des ...... ated ubiquitination of raptor.
@en
Ubiquitin hydrolase UCH-L1 des ...... ated ubiquitination of raptor.
@nl
prefLabel
Ubiquitin hydrolase UCH-L1 des ...... ated ubiquitination of raptor.
@en
Ubiquitin hydrolase UCH-L1 des ...... ated ubiquitination of raptor.
@nl
P2093
P2860
P356
P1476
Ubiquitin hydrolase UCH-L1 des ...... ated ubiquitination of raptor.
@en
P2093
Andrew L Feldman
Chittaranjan Das
Paul J Galardy
Sajjad Hussain
Stephen M Ansell
Steven C Ziesmer
P2860
P304
P356
10.1128/MCB.01389-12
P407
P577
2013-01-07T00:00:00Z