Histone deacetylase inhibitor AR-42 differentially affects cell-cycle transit in meningeal and meningioma cells, potently inhibiting NF2-deficient meningioma growth.
about
The Novel Small Molecule Inhibitor, OSU-T315, Suppresses Vestibular Schwannoma and Meningioma Growth by Inhibiting PDK2 Function in the AKT Pathway ActivationInhibition of SIRT2 in merlin/NF2-mutant Schwann cells triggers necrosis.Group I Paks as therapeutic targets in NF2-deficient meningioma.Role of Merlin/NF2 inactivation in tumor biology.Involvement of epimutations in meningioma.Novel histone deacetylase inhibitor AR-42 exhibits antitumor activity in pancreatic cancer cells by affecting multiple biochemical pathways.Inhibiting p21-Activated Kinase Induces Cell Death in Vestibular Schwannoma and Meningioma via Mitotic Catastrophe.Components of the eIF4F complex are potential therapeutic targets for malignant peripheral nerve sheath tumors and vestibular schwannomas.Overexpression of eIF4F components in meningiomas and suppression of meningioma cell growth by inhibiting translation initiation.A phase 1 trial of the HDAC inhibitor AR-42 in patients with multiple myeloma and T- and B-cell lymphomas.Generation of Noninvasive, Quantifiable, Orthotopic Animal Models for NF2-Associated Schwannoma and Meningioma.Traditional and systems biology based drug discovery for the rare tumor syndrome neurofibromatosis type 2.
P2860
Q30374421-30104312-B987-4FF8-A767-7C33CDB3C385Q35047921-B8C19B70-3497-45C0-A2FC-C2BD1F291D8BQ35273319-E3686569-F25A-4EFF-AF39-D6C030016C10Q36189820-BF371024-CB65-49C5-8DF4-730529DD27EAQ38452300-8F50F018-702E-4B1B-9CBB-3702BBCFB84CQ40084337-D4ACE472-35F6-4A4F-BD92-5D02DF8D78D0Q40534803-ECA3204E-6B17-45D3-921E-23688CFFAE97Q41139111-8E5DB7D9-159B-408A-84FC-9FA007486B94Q47144604-F2323855-5339-4D9D-BA65-3A5390433914Q47584543-5A063870-6DDA-4A08-8EFF-755264E82FDAQ51721478-CFCB6C48-0054-4DF1-B80A-094272300AEFQ55383186-C0B3276C-E80E-4FDB-A0FB-500C116E921E
P2860
Histone deacetylase inhibitor AR-42 differentially affects cell-cycle transit in meningeal and meningioma cells, potently inhibiting NF2-deficient meningioma growth.
description
2012 nî lūn-bûn
@nan
2012年の論文
@ja
2012年学术文章
@wuu
2012年学术文章
@zh-cn
2012年学术文章
@zh-hans
2012年学术文章
@zh-my
2012年学术文章
@zh-sg
2012年學術文章
@yue
2012年學術文章
@zh
2012年學術文章
@zh-hant
name
Histone deacetylase inhibitor ...... 2-deficient meningioma growth.
@en
Histone deacetylase inhibitor ...... 2-deficient meningioma growth.
@nl
type
label
Histone deacetylase inhibitor ...... 2-deficient meningioma growth.
@en
Histone deacetylase inhibitor ...... 2-deficient meningioma growth.
@nl
prefLabel
Histone deacetylase inhibitor ...... 2-deficient meningioma growth.
@en
Histone deacetylase inhibitor ...... 2-deficient meningioma growth.
@nl
P2093
P2860
P1433
P1476
Histone deacetylase inhibitor ...... 2-deficient meningioma growth.
@en
P2093
Abraham Jacob
Ching-Shih Chen
D Bradley Welling
Elena M Akhmametyeva
Janet L Oblinger
Long-Sheng Chang
Matthew L Bush
Sarah S Burns
Volker Senner
P2860
P304
P356
10.1158/0008-5472.CAN-12-1888
P407
P577
2012-11-14T00:00:00Z