Dispatched and scube mediate the efficient secretion of the cholesterol-modified hedgehog ligand.
about
Hedgehog Cholesterolysis: Specialized Gatekeeper to Oncogenic SignalingHedgehog Signaling in the Maintenance of Cancer Stem CellsOligomerization and endocytosis of Hedgehog is necessary for its efficient exovesicular secretionBridging the gap: heparan sulfate and Scube2 assemble Sonic hedgehog release complexes at the surface of producing cells.Secretion and signaling activities of lipoprotein-associated hedgehog and non-sterol-modified hedgehog in flies and mammalsScube3 is expressed in multiple tissues during development but is dispensable for embryonic survival in the mouseDisruption of Scube2 Impairs Endochondral Bone FormationFatty acylation of proteins: The long and the short of it.Control of signaling molecule range during developmental patterningA critical role of autocrine sonic hedgehog signaling in human CD138+ myeloma cell survival and drug resistance.Sonic hedgehog signaling in the lung. From development to disease.A new role for Hedgehogs in juxtacrine signaling.New chemical probes targeting cholesterylation of Sonic Hedgehog in human cells and zebrafish.Hedgehog signaling stimulates the conversion of cholesterol to steroids.A dynamic study of protein secretion and aggregation in the secretory pathway.Förster resonance energy transfer-based cholesterolysis assay identifies a novel hedgehog inhibitor.Morphogen transport.The Caenorhabditis elegans Excretory System: A Model for Tubulogenesis, Cell Fate Specification, and PlasticityMechanism of inhibition of the tumor suppressor Patched by Sonic Hedgehog.The notochord: structure and functions.Control of Adult Neurogenesis by Short-Range Morphogenic-Signaling Molecules.Protein lipid modifications--More than just a greasy ballast.Regulation of Hedgehog Signalling Inside and Outside the Cell.A Single Aspartate Coordinates Two Catalytic Steps in Hedgehog AutoprocessingCellular Cholesterol Directly Activates Smoothened in Hedgehog Signaling.Zebrafish genetics gets the Scube on Hedgehog secretion.Oxysterol binding to the extracellular domain of Smoothened in Hedgehog signaling.The Purkinje neuron: A central orchestrator of cerebellar neurogenesis.Neuropilin-1 promotes Hedgehog signaling through a novel cytoplasmic motif.Lipid metabolism fattens up hedgehog signaling.Hedgehog ligand biogenesisSonic Hedgehog Signaling in Thyroid Cancer.Matrix metalloproteinase-9 activity and a downregulated Hedgehog pathway impair blood-brain barrier function in an in vitro model of CNS tuberculosis.Protein Lipidation: Occurrence, Mechanisms, Biological Functions, and Enabling Technologies.Role of the ECM in notochord formation, function and disease.Cleavage activates Dispatched for Sonic Hedgehog ligand release.Hh-Np binds to DISP2Hh-Np binds SCUBE2 in the extracellular region to promote long-range signallingThe hedgehog pathway in nonalcoholic fatty liver disease.Sonic Hedgehog Signaling and Development of the Dentition.
P2860
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P2860
Dispatched and scube mediate the efficient secretion of the cholesterol-modified hedgehog ligand.
description
2012 nî lūn-bûn
@nan
2012年の論文
@ja
2012年論文
@yue
2012年論文
@zh-hant
2012年論文
@zh-hk
2012年論文
@zh-mo
2012年論文
@zh-tw
2012年论文
@wuu
2012年论文
@zh
2012年论文
@zh-cn
name
Dispatched and scube mediate t ...... erol-modified hedgehog ligand.
@en
Dispatched and scube mediate t ...... erol-modified hedgehog ligand.
@nl
type
label
Dispatched and scube mediate t ...... erol-modified hedgehog ligand.
@en
Dispatched and scube mediate t ...... erol-modified hedgehog ligand.
@nl
prefLabel
Dispatched and scube mediate t ...... erol-modified hedgehog ligand.
@en
Dispatched and scube mediate t ...... erol-modified hedgehog ligand.
@nl
P2093
P2860
P1433
P1476
Dispatched and scube mediate t ...... erol-modified hedgehog ligand.
@en
P2093
Adrian Salic
Cindy Y Jao
Hanna Tukachinsky
Ryan P Kuzmickas
P2860
P304
P356
10.1016/J.CELREP.2012.07.010
P577
2012-08-16T00:00:00Z