Multiple isozymes of cyclic nucleotide phosphodiesterase.
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Cloning and expression of cDNA for a human low-Km, rolipram-sensitive cyclic AMP phosphodiesterasePDE4 inhibition enhances hippocampal synaptic plasticity in vivo and rescues MK801-induced impairment of long-term potentiation and object recognition memory in an animal model of psychosisMolecular cloning of DNA encoding a calmodulin-dependent phosphodiesterase enriched in striatum.cAMP compartmentation is responsible for a local activation of cardiac Ca2+ channels by beta-adrenergic agonistsSarcoplasmic reticulum-associated cyclic adenosine 5'-monophosphate phosphodiesterase activity in normal and failing human hearts.Beta-adrenergic stimulation of adenine nucleotide catabolism and purine release in human adipocytes.Anti-spasmogenic activity of isoenzyme-selective phosphodiesterase inhibitors in guinea-pig trachealis.A spontaneous change in the intracellular cyclic AMP level in Aspergillus niger is influenced by the sucrose concentration in the medium and by light.Mechanisms whereby extracellular adenosine 3',5'-monophosphate inhibits phosphate transport in cultured opossum kidney cells and in rat kidney. Physiological implication.Inhibition of eosinophil cyclic nucleotide PDE activity and opsonised zymosan-stimulated respiratory burst by 'type IV'-selective PDE inhibitors.Stimulation of the hypothalamo-pituitary-adrenal axis in the rat by the type 4 phosphodiesterase (PDE-4) inhibitor, denbufylline.Estimating the magnitude of near-membrane PDE4 activity in living cellsIrish setter dogs affected with rod/cone dysplasia contain a nonsense mutation in the rod cGMP phosphodiesterase beta-subunit gene.Incomplete reversal of beta-adrenoceptor desensitization in human and guinea-pig cardiomyocytes by cyclic nucleotide phosphodiesterase inhibitorsIn vivo assessment of local phosphodiesterase activity using tailored cyclic nucleotide-gated channels as cAMP sensors.Role of cGMP and cGMP-dependent protein kinase in nitrovasodilator inhibition of agonist-evoked calcium elevation in human platelets.Phosphodiesterase inhibitors: new opportunities for the treatment of asthma.Ca2+ current is regulated by cyclic GMP-dependent protein kinase in mammalian cardiac myocytes.Identification of a nonsense mutation in the rod photoreceptor cGMP phosphodiesterase beta-subunit gene of the rd mouse.Identification of a noncatalytic cGMP-binding domain conserved in both the cGMP-stimulated and photoreceptor cyclic nucleotide phosphodiesterasesComplete cDNA sequences of mouse rod photoreceptor cGMP phosphodiesterase alpha- and beta-subunits, and identification of beta'-, a putative beta-subunit isozyme produced by alternative splicing of the beta-subunit gene.The presence of five cyclic nucleotide phosphodiesterase isoenzyme activities in bovine tracheal smooth muscle and the functional effects of selective inhibitors.Further investigation into the signal transduction mechanism of the 5-HT4-like receptor in the circular smooth muscle of human colon.Prostaglandins and muscarinic agonists induce cyclic AMP attenuation by two distinct mechanisms in the pregnant-rat myometrium. Interaction between cyclic AMP and Ca2+ signals.A cell culture model of the blood-brain barrier.The effects of siguazodan, a selective phosphodiesterase inhibitor, on human platelet function.Effects of selective phosphodiesterase inhibition on cyclic AMP hydrolysis in rat cerebral cortical slices.The effect of cyclic AMP and cyclic GMP phosphodiesterase inhibitors on the superoxide burst of guinea-pig peritoneal macrophages.Mechanism of the cardiovascular activity of laudanosine: comparison with papaverine and other benzylisoquinolines.Characterization of calmodulin-dependent cyclic nucleotide phosphodiesterase isoenzymes.Role of phosphodiesterases III and IV in the modulation of vascular cyclic AMP content by the NO/cyclic GMP pathway.Chronotropic and inotropic actions of amrinone, carbazeran and isobutylmethyl xanthine: role of phosphodiesterase inhibition.Cardiotonic actions of selective phosphodiesterase inhibitors in rat isolated ventricular cardiomyocytes.Cross-talk between glucagon- and adenosine-mediated signalling systems in rat hepatocytes: effects on cyclic AMP-phosphodiesterase activity.Pharmacological and biochemical effects of the cardiotonic agent Org10325 in isolated cardiac and vascular tissue preparations.Multiple actions of glaucine on cyclic nucleotide phosphodiesterases, alpha 1-adrenoceptor and benzothiazepine binding site at the calcium channel.Time-course changes in content and fatty acid composition of phosphatidic acid from rat thymocytes during concanavalin A stimulation.The ability of denbufylline to inhibit cyclic nucleotide phosphodiesterase and its affinity for adenosine receptors and the adenosine re-uptake site.Regulation of cerebral microvascular permeability by histamine in the anaesthetized rat.
P2860
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P2860
Multiple isozymes of cyclic nucleotide phosphodiesterase.
description
1988 nî lūn-bûn
@nan
1988年の論文
@ja
1988年学术文章
@wuu
1988年学术文章
@zh-cn
1988年学术文章
@zh-hans
1988年学术文章
@zh-my
1988年学术文章
@zh-sg
1988年學術文章
@yue
1988年學術文章
@zh
1988年學術文章
@zh-hant
name
Multiple isozymes of cyclic nucleotide phosphodiesterase.
@en
Multiple isozymes of cyclic nucleotide phosphodiesterase.
@nl
type
label
Multiple isozymes of cyclic nucleotide phosphodiesterase.
@en
Multiple isozymes of cyclic nucleotide phosphodiesterase.
@nl
prefLabel
Multiple isozymes of cyclic nucleotide phosphodiesterase.
@en
Multiple isozymes of cyclic nucleotide phosphodiesterase.
@nl
P1476
Multiple isozymes of cyclic nucleotide phosphodiesterase.
@en
P2093
P577
1988-01-01T00:00:00Z