Global H3K27 trimethylation and EZH2 abundance in breast tumor subtypes. - Wikidata - wikimedia - TriplyDB

Global H3K27 trimethylation and EZH2 abundance in breast tumor subtypes.

Global H3K27 trimethylation and EZH2 abundance in breast tumor subtypes.

http://www.wikidata.org/entity/Q39319266

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Polycomb repressive complex's evolutionary conserved function: the role of EZH2 status and cellular background Exosomes-mediate microRNAs transfer in breast cancer chemoresistance regulation PAT-H-MS coupled with laser microdissection to study histone post-translational modifications in selected cell populations from pathology samples.Prognostic value of polycomb proteins EZH2, BMI1 and SUZ12 and histone modification H3K27me3 in colorectal cancer Chemical profiling of the genome with anti-cancer drugs defines target specificities.Small-molecular modulators of cancer-associated epigenetic mechanisms.The methyltransferase EZH2 is not required for mammary cancer development, although high EZH2 and low H3K27me3 correlate with poor prognosis of ER-positive breast cancers Epigenetic and metabolic regulation of breast cancer stem cells.3-Deazaneplanocin A (DZNep), an inhibitor of the histone methyltransferase EZH2, induces apoptosis and reduces cell migration in chondrosarcoma cells.EZH2 as a potential target in cancer therapy.Genetic alterations of histone lysine methyltransferases and their significance in breast cancer Pathology Tissue-quantitative Mass Spectrometry Analysis to Profile Histone Post-translational Modification Patterns in Patient Samples.Therapeutic Implications of Cellular Heterogeneity and Plasticity in Breast Cancer Immunohistochemical and genomic profiles of diffuse large B-cell lymphomas: implications for targeted EZH2 inhibitor therapy?Non-Canonical EZH2 Transcriptionally Activates RelB in Triple Negative Breast Cancer Impaired PRC2 activity promotes transcriptional instability and favors breast tumorigenesis NBAT1 suppresses breast cancer metastasis by regulating DKK1 via PRC2.The Polycomb Group Protein EZH2 Impairs DNA Damage Repair Gene Expression in Human Uterine Fibroids EZH2 overexpression in different immunophenotypes of breast carcinoma and association with clinicopathologic features.A quantitative atlas of histone modification signatures from human cancer cells HIFI-α activation underlies a functional switch in the paradoxical role of Ezh2/PRC2 in breast cancer.Keeping an open mind: highlights and controversies of the breast cancer stem cell theory EZH2 knockdown suppresses the growth and invasion of human inflammatory breast cancer cells.STAT3 signaling drives EZH2 transcriptional activation and mediates poor prognosis in gastric cancer.Multidrug-resistant breast cancer: current perspectives.The role of maintenance proteins in the preservation of epithelial cell identity during mammary gland remodeling and breast cancer initiation.Update of research on the role of EZH2 in cancer progression.Epigenetic mechanisms of breast cancer: an update of the current knowledge.Contemporary proteomic strategies for clinical epigenetic research and potential impact for the clinic.Recent advances in mass spectrometry analysis of histone post-translational modifications: potential clinical impact of the PAT-H-MS approach.LncRNA-ANCR down-regulation suppresses invasion and migration of colorectal cancer cells by regulating EZH2 expression.Association between EZH2 expression, silencing of tumor suppressors and disease outcome in solid tumors.miR-125b-1 is repressed by histone modifications in breast cancer cell lines.Epigenetic silencing of microRNA-218 via EZH2-mediated H3K27 trimethylation is involved in malignant transformation of HBE cells induced by cigarette smoke extract.Dysregulation of histone methyltransferases in breast cancer - Opportunities for new targeted therapies?Nicotine induces alteration of H3K27 demethylase UTX in kidney cancer cell.Proximal and distal regulation of the HYAL1 gene cluster by the estrogen receptor α in breast cancer cells.Identification of Polycomb Group Protein EZH2-Mediated DNA Mismatch Repair Gene MSH2 in Human Uterine Fibroids.Genome methylation patterns in male breast cancer - Identification of an epitype with hypermethylation of polycomb target genes.The Epigenetic Landscape of Promoter Genome-wide Analysis in Breast Cancer

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Global H3K27 trimethylation and EZH2 abundance in breast tumor subtypes.

http://www.wikidata.org/entity/Q39319266

description

2012 nî lūn-bûn

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2012年学术文章

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2012年学术文章

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2012年学术文章

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2012年学术文章

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2012年学术文章

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2012年學術文章

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2012年學術文章

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2012年學術文章

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name

Global H3K27 trimethylation and EZH2 abundance in breast tumor subtypes.

@en

Global H3K27 trimethylation and EZH2 abundance in breast tumor subtypes.

@nl

type

label

Global H3K27 trimethylation and EZH2 abundance in breast tumor subtypes.

@en

Global H3K27 trimethylation and EZH2 abundance in breast tumor subtypes.

@nl

prefLabel

Global H3K27 trimethylation and EZH2 abundance in breast tumor subtypes.

@en

Global H3K27 trimethylation and EZH2 abundance in breast tumor subtypes.

@nl

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J.MOLONC.2012.06.002

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Molecular Oncology

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Global H3K27 trimethylation and EZH2 abundance in breast tumor subtypes.

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Cecilia Hegardt

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Dorthe Grabau

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Jillian Howlin

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Karolina Holm

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Kristina Lövgren

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Lisa Rydén

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Mårten Fernö

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Olle Stål

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Pär-Ola Bendahl

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Sofia Gruvberger-Saal

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The CD44+/CD24- phenotype is enriched in basal-like breast tumors

Composition and histone substrates of polycomb repressive group complexes change during cellular differentiation

The Polycomb group protein EZH2 directly controls DNA methylation

Genomic subtypes of breast cancer identified by array-comparative genomic hybridization display distinct molecular and clinical characteristics

A collection of breast cancer cell lines for the study of functionally distinct cancer subtypes

EZH2 is a marker of aggressive breast cancer and promotes neoplastic transformation of breast epithelial cells

Somatic mutations altering EZH2 (Tyr641) in follicular and diffuse large B-cell lymphomas of germinal-center origin.

Somatic mutations of the histone methyltransferase gene EZH2 in myelodysplastic syndromes.

Gene expression patterns of breast carcinomas distinguish tumor subclasses with clinical implications

Molecular portraits of human breast tumours

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10.1016/J.MOLONC.2012.06.002

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5

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6

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Markus Ringnér

Per-Uno Malmström

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2012-06-20T00:00:00Z

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228330108

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5528390

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