Novel 5-substituted benzyloxy-2-arylbenzofuran-3-carboxylic acids as calcium activated chloride channel inhibitors.
about
Calcium-activated chloride channel ANO1 promotes breast cancer progression by activating EGFR and CAMK signalingAntagonists of the TMEM16A calcium-activated chloride channel modulate airway smooth muscle tone and intracellular calcium.Inhibition of TMEM16A expression suppresses growth and invasion in human colorectal cancer cellsPotentiation of ΔF508- and G551D-CFTR-Mediated Cl- Current by Novel HydroxypyrazolinesVariomics screen identifies the re-entrant loop of the calcium-activated chloride channel ANO1 that facilitates channel activation.Synthesis and evaluation of 5,6-disubstituted thiopyrimidine aryl aminothiazoles as inhibitors of the calcium-activated chloride channel TMEM16A/Ano1.Small molecule-facilitated degradation of ANO1 protein: a new targeting approach for anticancer therapeutics.Synthesis of some novel 4-arylidene pyrazoles as potential antimicrobial agents.Synthesis and biological evaluation of benzenesulphonamide-bearing 1,4,5-trisubstituted-1,2,3-triazoles possessing human carbonic anhydrase I, II, IV, and IX inhibitory activity.Development and validation of HTS assay for screening the calcium-activated chloride channel modulators in TMEM16A stably expressed CHO cells.Functional comparison of anoctamin 1 antagonists on human uterine smooth muscle contractility and excitability.
P2860
Q24602862-3C5B8BD1-A9AD-44F1-9305-A011449EC459Q27318373-4CF4CD15-2A16-4E54-86C6-48626E085BEDQ28542858-2D3CBE83-E4BE-4352-A375-86810B23A4E6Q28550065-2F8675C1-5F6F-400E-A13D-CF7C5B1D5F48Q30368943-6D5DD535-1A0F-4E44-96B4-02AC385A6FBDQ35900576-F5DF66C5-6943-4223-B62B-81C27B83469BQ39018217-18ED9AD7-3B56-4AAF-9C41-B6B9795B998DQ42106940-28185EE1-B5D3-4270-817C-1A60F502B80DQ47824587-148495E0-F667-47D0-9453-AF0BC20E0B21Q51750440-3E54FC71-8843-49A4-B7CE-6C74501A833EQ55267330-28659846-18C3-412F-AD4E-2A1AEB2C1E98
P2860
Novel 5-substituted benzyloxy-2-arylbenzofuran-3-carboxylic acids as calcium activated chloride channel inhibitors.
description
2012 nî lūn-bûn
@nan
2012年の論文
@ja
2012年学术文章
@wuu
2012年学术文章
@zh-cn
2012年学术文章
@zh-hans
2012年学术文章
@zh-my
2012年学术文章
@zh-sg
2012年學術文章
@yue
2012年學術文章
@zh
2012年學術文章
@zh-hant
name
Novel 5-substituted benzyloxy- ...... d chloride channel inhibitors.
@en
Novel 5-substituted benzyloxy- ...... d chloride channel inhibitors.
@nl
type
label
Novel 5-substituted benzyloxy- ...... d chloride channel inhibitors.
@en
Novel 5-substituted benzyloxy- ...... d chloride channel inhibitors.
@nl
prefLabel
Novel 5-substituted benzyloxy- ...... d chloride channel inhibitors.
@en
Novel 5-substituted benzyloxy- ...... d chloride channel inhibitors.
@nl
P2093
P2860
P1476
Novel 5-substituted benzyloxy- ...... d chloride channel inhibitors.
@en
P2093
A S Verkman
Pawan K Sharma
Satish Kumar
Wan Namkung
P2860
P304
P356
10.1016/J.BMC.2012.05.074
P407
P577
2012-06-06T00:00:00Z