Maintenance of acinar cell organization is critical to preventing Kras-induced acinar-ductal metaplasia. - Wikidata - wikimedia - TriplyDB

Maintenance of acinar cell organization is critical to preventing Kras-induced acinar-ductal metaplasia.

Maintenance of acinar cell organization is critical to preventing Kras-induced acinar-ductal metaplasia.

http://www.wikidata.org/entity/Q39337159

about

Deciphering the role of hedgehog signaling in pancreatic cancer Reserve stem cells: Differentiated cells reprogram to fuel repair, metaplasia, and neoplasia in the adult gastrointestinal tract Silencing Mist1 Gene Expression Is Essential for Recovery from Acute Pancreatitis Therapeutic potential of targeting acinar cell reprogramming in pancreatic cancer A Revised Classification System and Recommendations From the Baltimore Consensus Meeting for Neoplastic Precursor Lesions in the Pancreas Regulation of Cellular Identity in Cancer Interleukin-6 is required for pancreatic cancer progression by promoting MAPK signaling activation and oxidative stress resistance Molecular imaging in pancreatic cancer--a roadmap for therapeutic decisions.Tumor protein D52 controls trafficking of an apical endolysosomal secretory pathway in pancreatic acinar cells.RAB26 coordinates lysosome traffic and mitochondrial localization.MAPK signaling is required for dedifferentiation of acinar cells and development of pancreatic intraepithelial neoplasia in mice.PD2/Paf1 depletion in pancreatic acinar cells promotes acinar-to-ductal metaplasia.The tumor suppressor rpl36 restrains KRAS(G12V)-induced pancreatic cancer.PI3K regulation of RAC1 is required for KRAS-induced pancreatic tumorigenesis in mice.IER3 supports KRASG12D-dependent pancreatic cancer development by sustaining ERK1/2 phosphorylation.Dicer regulates differentiation and viability during mouse pancreatic cancer initiation Dicer is required for maintenance of adult pancreatic acinar cell identity and plays a role in Kras-driven pancreatic neoplasia.The basic helix-loop-helix transcription factor E47 reprograms human pancreatic cancer cells to a quiescent acinar state with reduced tumorigenic potential.Wild-Type Hras Suppresses the Earliest Stages of Tumorigenesis in a Genetically Engineered Mouse Model of Pancreatic Cancer.Ductal metaplasia in oesophageal submucosal glands is associated with inflammation and oesophageal adenocarcinoma Quantitative Proteomic Analysis of Differentially Expressed Protein Profiles Involved in Pancreatic Ductal Adenocarcinoma TGF-β1 promotes acinar to ductal metaplasia of human pancreatic acinar cells.Stromal ETS2 Regulates Chemokine Production and Immune Cell Recruitment during Acinar-to-Ductal Metaplasia.Genetic ablation of Smoothened in pancreatic fibroblasts increases acinar-ductal metaplasia.MIST1 and PTF1 Collaborate in Feed-forward Regulatory Loops that Maintain the Pancreatic Acinar Phenotype in Adult Mice.PDX1 dynamically regulates pancreatic ductal adenocarcinoma initiation and maintenance.Pathogenesis of pancreatic cancer: lessons from animal models.Far-Red and Near-Infrared Seminaphthofluorophores for Targeted Pancreatic Cancer Imaging.Therapeutic actions of melatonin on gastrointestinal cancer development and progression.Activated K-RAS and its effect on morphological appearance.Acinar cell plasticity and development of pancreatic ductal adenocarcinoma.Systematic Review and Case Series Report of Acinar Cell Carcinoma of the Pancreas.Nr5a2 maintains acinar cell differentiation and constrains oncogenic Kras-mediated pancreatic neoplastic initiation.Differentiation and Inflammation: 'Best Enemies' in Gastrointestinal Carcinogenesis.Pancreatic Acinar Cell 3-Dimensional Culture.YAP1 and TAZ Control Pancreatic Cancer Initiation in Mice by Direct Up-regulation of JAK-STAT3 Signaling.A screen for inducers of bHLH activity identifies pitavastatin as a regulator of p21, Rb phosphorylation and E2F target gene expression in pancreatic cancer.Porcine Esophageal Submucosal Gland Culture Model Shows Capacity for Proliferation and Differentiation Plasticity and dedifferentiation within the pancreas: development, homeostasis, and disease.Identification of Sox9-dependent acinar-to-ductal reprogramming as the principal mechanism for initiation of pancreatic ductal adenocarcinoma.

P2860

Q26747103-74BDE2F9-0ED3-47AE-B2B6-EE7C0BE298AF Q26801731-3B878BCB-F4F2-41C1-857F-8FB8944657DA Q27334054-32A9E770-BAC0-4851-A21B-837121EEAEAF Q28068998-EE252573-2A84-4238-8CA9-E116BD6126BB Q28082890-30D7EFB2-F5D9-4E2C-96F3-DE0C99B3CAA5 Q28086849-EA23E931-A42D-413C-8616-D710294C9875 Q28504893-47380612-6FA4-4562-85F4-E59A6B54FB87 Q30423854-6F553BB0-0298-4CF3-91C1-CFFB2EDBF0B5 Q30544009-74716BEE-0205-41A2-A71E-B2EE9261E1CC Q30573041-24FF1F6A-3C5A-4817-9238-055A388D0069 Q33680759-F75D4390-3D7E-4BA2-8E7A-66B8ACE53136 Q34101017-BF79C54B-EA30-44C4-9F3C-B39F2AA88696 Q34589948-B85C8ACC-368F-4651-AF53-33F9C0130C74 Q34616196-59C34BBF-37E0-45CB-A552-2C884BFE612E Q35140072-60742FE5-5069-4676-B322-D988BEB2D955 Q35161464-FF027855-2B22-44F7-8B70-F62AC0DCE331 Q35432049-8CC0444F-5547-4C5D-91A0-DE51EE3BD6D6 Q35732360-5A3D7B8D-4F2E-47B7-A0D4-A8C534A3966E Q35801876-91716E2C-D01F-455D-819D-FE2F4F11D48C Q36117607-62277C12-770A-4257-9FA3-9B58E51B5BBF Q36367896-FB4186C8-E230-44A8-A308-A29F793B0B14 Q37147887-10ECE261-1019-4BA3-AAFF-8A7EE2331B02 Q37273793-ABD3C2EC-451F-4D24-9295-62FE4206107A Q37343012-8EC1D0BA-0AF8-4FEE-B72D-1476D95599C7 Q37413667-37C1E09F-E072-4D08-94BC-C9E2BB68BABD Q37587988-2A2B1B28-C4A6-4A55-804F-6F5205B0CD88 Q37589374-D4D14658-99ED-40F2-8271-53F9F9AF8FCC Q37618186-95407D4F-DE15-4C59-8679-B55ACF730F59 Q38169160-02CA3FE9-F27D-4B41-8D71-C8A8108C607C Q38222722-47224DDE-A99D-4557-9329-E0CEF2592BA2 Q38922230-198764CF-D3EF-4F25-86A5-D70C96E2B950 Q39008039-804B911D-86EE-4124-B787-D00AF5BBDFAA Q39156056-22534875-0E9D-4EAF-A235-F405FE313468 Q39384816-1716BA74-F116-4270-B38B-63EC408F7127 Q39564156-82A5411E-0A1A-4FA0-8DFF-1C464CEE82F9 Q40989829-0360E0E3-85EF-4866-8A11-C7DDD7FC8349 Q41593086-CE44FF38-36F0-4E90-86A9-B79DF72887D0 Q41705186-8119AB09-69C1-4CCD-831F-F60500E715FF Q41737306-543B220B-109A-45EB-8B6B-9B8FF6CF9135 Q41856856-28CB7B98-8FC1-444E-B379-6518713372E4

P2860

Maintenance of acinar cell organization is critical to preventing Kras-induced acinar-ductal metaplasia.

http://www.wikidata.org/entity/Q39337159

description

2012 nî lūn-bûn

@nan

2012年の論文

@ja

2012年学术文章

@wuu

2012年学术文章

@zh-cn

2012年学术文章

@zh-hans

2012年学术文章

@zh-my

2012年学术文章

@zh-sg

2012年學術文章

@yue

2012年學術文章

@zh

2012年學術文章

@zh-hant

name

Maintenance of acinar cell org ...... uced acinar-ductal metaplasia.

@en

Maintenance of acinar cell org ...... uced acinar-ductal metaplasia.

@nl

type

label

Maintenance of acinar cell org ...... uced acinar-ductal metaplasia.

@en

Maintenance of acinar cell org ...... uced acinar-ductal metaplasia.

@nl

prefLabel

Maintenance of acinar cell org ...... uced acinar-ductal metaplasia.

@en

Maintenance of acinar cell org ...... uced acinar-ductal metaplasia.

@nl

P1433

Q39337159-5A3B6605-8777-417C-8E6C-14B26DAF3F41

P1476

Q39337159-87414967-1642-4B23-BD6C-20911CE4E465

P2093

Q39337159-1070E376-1845-4363-80F3-A0DEC5389465

Q39337159-93218EBF-D41A-4D17-AF5D-F14AA50E720B

Q39337159-BE741AFF-27E1-44B0-8E28-08B5617C48F7

Q39337159-DC5D68C2-CDF7-4960-A89B-5F8B0C9CEE07

Q39337159-F0155687-4782-4D8C-BF22-CE73C9DF0752

P2860

Q39337159-05FC0BF7-A386-40A5-8F10-DFA71B341EC2

Q39337159-1BA779C5-8D8D-4D24-BAC3-3232A99F0840

Q39337159-25E9323E-45C7-450D-9042-07C0AF6188A0

Q39337159-261E0D6D-EDF5-4C86-B23C-1ACD68A818DB

Q39337159-2728B588-A26A-4E98-8C3C-AAACE20E07F5

Q39337159-2835A84B-333B-482B-8078-BD2691C570C9

Q39337159-291E7A0E-FEDA-4CAF-BB31-8B76F6F6BF67

Q39337159-2A49CF41-6F7E-453D-9967-3ECB09E3F583

Q39337159-31DD88EB-DD09-4676-B7DF-DD889E7BC975

Q39337159-32DD246D-6D37-42FC-8E61-BDD25B563186

P2888

Q39337159-2EB9D87E-92BE-4353-87EC-DE5D64E77116

P304

Q39337159-84630980-CAFE-4B5A-9B72-60A49CEAC2C5

P31

Q39337159-55A16A14-4553-4F62-A925-68DF4FDB7AF2

P356

Q39337159-EAD8795D-FED7-4BD8-B412-4BCC3E9BF5BA

P407

Q39337159-BD24BA40-6BEA-462C-B3B4-D4B368F5E540

P433

Q39337159-76622C96-2DED-41B5-A505-DAED5CD143A9

P478

Q39337159-30F47DE8-5F88-4EEB-85A2-EE3495200640

P50

Q39337159-B33BE039-19AF-4854-96DA-0AE25B934153

P577

Q39337159-7D0414F9-390F-4D09-9081-595A183ADA6F

P5875

Q39337159-64F914F2-5408-4CDD-B531-9966F3CCED09

P698

Q39337159-880FE34D-8C3F-41DE-8EFF-64139DF5096F

P932

Q39337159-DD6EC488-54DF-41FE-9639-A799E1C5B953

P356

P1433

P1476

Maintenance of acinar cell org ...... duced acinar-ductal metaplasia

@en

P2093

C Qu

http://www.w3.org/2001/XMLSchema#string

D Barney

http://www.w3.org/2001/XMLSchema#string

D DiRenzo

http://www.w3.org/2001/XMLSchema#string

D Miley

http://www.w3.org/2001/XMLSchema#string

S F Konieczny

http://www.w3.org/2001/XMLSchema#string

P2860

The bHLH transcription factor Mist1 is required to maintain exocrine pancreas cell organization and acinar cell identity

BRAF and FBXW7 (CDC4, FBW7, AGO, SEL10) mutations in distinct subsets of pancreatic cancer: potential therapeutic targets

Acute pancreatitis accelerates initiation and progression to pancreatic cancer in mice expressing oncogenic Kras in the nestin cell lineage

Cancer statistics, 2010

Targeting RAS signalling pathways in cancer therapy

The maturation of mucus-secreting gastric epithelial progenitors into digestive-enzyme secreting zymogenic cells requires Mist1

Inhibition of Mist1 homodimer formation induces pancreatic acinar-to-ductal metaplasia

Trp53R172H and KrasG12D cooperate to promote chromosomal instability and widely metastatic pancreatic ductal adenocarcinoma in mice

Preinvasive and invasive ductal pancreatic cancer and its early detection in the mouse

KRAS2 mutations in human pancreatic acinar-ductal metaplastic lesions are limited to those with PanIN: implications for the human pancreatic cancer cell of origin

P2888

P304

1950-1958

http://www.w3.org/2001/XMLSchema#string

P31

scholarly article

P356

10.1038/ONC.2012.210

http://www.w3.org/2001/XMLSchema#string

P407

P433

15

http://www.w3.org/2001/XMLSchema#string

P478

32

http://www.w3.org/2001/XMLSchema#string

P50

P577

2012-06-04T00:00:00Z

http://www.w3.org/2001/XMLSchema#dateTime

P5875

225186055

http://www.w3.org/2001/XMLSchema#string

P698

22665051

http://www.w3.org/2001/XMLSchema#string

P932

3435479

http://www.w3.org/2001/XMLSchema#string