Targeting COX-2 and EP4 to control tumor growth, angiogenesis, lymphangiogenesis and metastasis to the lungs and lymph nodes in a breast cancer model.
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Lymphatic Vessels, Inflammation, and Immunity in Skin CancerE-type prostanoid receptor 4 (EP4) in disease and therapyDeciphering Pro-Lymphangiogenic Programs during Mammary Involution and Postpartum Breast CancerThe impact of low-dose carcinogens and environmental disruptors on tissue invasion and metastasisParicalcitol Pretreatment Attenuates Renal Ischemia-Reperfusion Injury via Prostaglandin E2 Receptor EP4 Pathway.Minireview: Obesity and breast cancer: a tale of inflammation and dysregulated metabolismERK1/2/COX-2/PGE2 signaling pathway mediates GPR91-dependent VEGF release in streptozotocin-induced diabetes.Inflammatory lymphangiogenesis in postpartum breast tissue remodelingProstaglandin E2 and the EP receptors in malignancy: possible therapeutic targets?The tumor promoting activity of the EP4 receptor for prostaglandin E2 in murine skin.Prostaglandin receptors EP1-4 as a potential marker for clinical outcome in urothelial bladder cancer.The role of CCL21/CCR7 chemokine axis in breast cancer-induced lymphangiogenesis.Prostaglandin E2 receptor EP4 as the common target on cancer cells and macrophages to abolish angiogenesis, lymphangiogenesis, metastasis, and stem-like cell functionsThe MAPK signaling pathway mediates the GPR91-dependent release of VEGF from RGC-5 cells.Recent prediagnostic aspirin use, lymph node involvement, and 5-year mortality in women with stage I-III breast cancer: a nationwide population-based cohort studyAnalysis of the correlation between P53 and Cox-2 expression and prognosis in esophageal cancer.Molecular inhibition of prostaglandin E2 with GW627368X: Therapeutic potential and preclinical safety assessment in mouse sarcoma model.PGE2 promotes breast cancer-associated lymphangiogenesis by activation of EP4 receptor on lymphatic endothelial cells.Anti-tumor enhancement of Fei-Liu-Ping ointment in combination with celecoxib via cyclooxygenase-2-mediated lung metastatic inflammatory microenvironment in Lewis lung carcinoma xenograft mouse modelProstaglandin E2 stimulates normal bronchial epithelial cell growth through induction of c-Jun and PDK1, a kinase implicated in oncogenesis.The SK-N-AS human neuroblastoma cell line develops osteolytic bone metastases with increased angiogenesis and COX-2 expression.Doxorubicin and deracoxib adjuvant therapy for canine splenic hemangiosarcoma: a pilot study.Inhibition of lymphangiogenesis and angiogenesis in breast tumor xenografts and lymph nodes by a peptide derived from transmembrane protein 45AThe syndecan-4/protein kinase Cα pathway mediates prostaglandin E2-induced extracellular regulated kinase (ERK) activation in endothelial cells and angiogenesis in vivo.The effect of celecoxib on tumor growth in ovarian cancer cells and a genetically engineered mouse model of serous ovarian cancer.MMP-7 is upregulated by COX-2 and promotes proliferation and invasion of lung adenocarcinoma cells.Multiple drug resistance-associated protein (MRP4) exports prostaglandin E2 (PGE2) and contributes to metastasis in basal/triple negative breast cancer.Prostaglandin EP4 antagonists.Molecular mechanisms of target recognition by lipid GPCRs: relevance for cancer.The EP4 antagonist, L-161,982, induces apoptosis, cell cycle arrest, and inhibits prostaglandin E2-induced proliferation in oral squamous carcinoma Tca8113 cells.Immunomodulation of RAW 264.7 murine macrophage functions and antioxidant activities of 11 plant extracts.An EP4 antagonist ONO-AE3-208 suppresses cell invasion, migration, and metastasis of prostate cancer.A practical and sensitive method of quantitating lymphangiogenesis in vivo.Concurrent targeting of eicosanoid receptor 1/eicosanoid receptor 4 receptors and COX-2 induces synergistic apoptosis in Kaposi's sarcoma-associated herpesvirus and Epstein-Barr virus associated non-Hodgkin lymphoma cell lines.Low expression of microRNA-143 is related to degenerative scoliosis possibly by regulation of cyclooxygenase-2 expression.The Adjuvant Nutritional Intervention in Cancer (ANICA) Trial.Association of ERAP1, IL23R and PTGER4 Polymorphisms with Radiographic Severity of Ankylosing Spondylitis.Expression of prostaglandin E2 and EP receptors in human papillary thyroid carcinoma.Compound Wumei Powder Inhibits the Invasion and Metastasis of Gastric Cancer via Cox-2/PGE2-PI3K/AKT/GSK3β/β-Catenin Signaling Pathway.COX-2 induces oncogenic micro RNA miR655 in human breast cancer.
P2860
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P2860
Targeting COX-2 and EP4 to control tumor growth, angiogenesis, lymphangiogenesis and metastasis to the lungs and lymph nodes in a breast cancer model.
description
2012 nî lūn-bûn
@nan
2012年の論文
@ja
2012年論文
@yue
2012年論文
@zh-hant
2012年論文
@zh-hk
2012年論文
@zh-mo
2012年論文
@zh-tw
2012年论文
@wuu
2012年论文
@zh
2012年论文
@zh-cn
name
Targeting COX-2 and EP4 to con ...... odes in a breast cancer model.
@en
Targeting COX-2 and EP4 to con ...... odes in a breast cancer model.
@nl
type
label
Targeting COX-2 and EP4 to con ...... odes in a breast cancer model.
@en
Targeting COX-2 and EP4 to con ...... odes in a breast cancer model.
@nl
prefLabel
Targeting COX-2 and EP4 to con ...... odes in a breast cancer model.
@en
Targeting COX-2 and EP4 to con ...... odes in a breast cancer model.
@nl
P2093
P2860
P1476
Targeting COX-2 and EP4 to con ...... odes in a breast cancer model.
@en
P2093
Gannareddy V Girish
Mousumi Majumder
Peeyush K Lala
Takayuki Maruyama
Vik Mohindra
Xiping Xin
P2860
P2888
P304
P356
10.1038/LABINVEST.2012.90
P577
2012-05-28T00:00:00Z
P5875
P6179
1009402805