The dopamine metabolite aminochrome inhibits mitochondrial complex I and modifies the expression of iron transporters DMT1 and FPN1.
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Interactions of iron, dopamine and neuromelanin pathways in brain aging and Parkinson's diseaseInflammation alters the expression of DMT1, FPN1 and hepcidin, and it causes iron accumulation in central nervous system cellsT2 relaxometry using 3.0-tesla magnetic resonance imaging of the brain in early- and late-onset restless legs syndrome.Direct intranigral injection of dopaminochrome causes degeneration of dopamine neuronsComparison of Monoamine Oxidase Inhibitors in Decreasing Production of the Autotoxic Dopamine Metabolite 3,4-Dihydroxyphenylacetaldehyde in PC12 Cells.DT-Diaphorase Prevents Aminochrome-Induced Alpha-Synuclein Oligomer Formation and Neurotoxicity.Brain iron deficiency in idiopathic restless legs syndrome measured by quantitative magnetic susceptibility at 7 tesla.Brain iron homeostasis: from molecular mechanisms to clinical significance and therapeutic opportunitiesIron in neurodegenerative disorders of protein misfolding: a case of prion disorders and Parkinson's disease.Impact of Plant-Derived Flavonoids on Neurodegenerative Diseases.Aminochrome Toxicity is Mediated by Inhibition of Microtubules Polymerization Through the Formation of Adducts with Tubulin.Glutathione transferase-M2-2 secreted from glioblastoma cell protects SH-SY5Y cells from aminochrome neurotoxicity.Protective effects of nicotine against aminochrome-induced toxicity in substantia nigra derived cells: implications for Parkinson's diseaseCommentary: Evaluation of Models of Parkinson's Disease.On the role of endogenous neurotoxins and neuroprotection in Parkinson's disease.Dopamine oxidation and autophagyAminochrome induces dopaminergic neuronal dysfunction: a new animal model for Parkinson's disease.Commentary: A Humanized Clinically Calibrated Quantitative Systems Pharmacology Model for Hypokinetic Motor Symptoms in Parkinson's Disease.Neurotoxin mechanisms and processes relevant to Parkinson's disease: an update.Neuroprotective effect of aqueous extract of Selaginella delicatula as evidenced by abrogation of rotenone-induced motor deficits, oxidative dysfunctions, and neurotoxicity in mice.Development of an iron-selective antioxidant probe with protective effects on neuronal function.Biological plausibility of the gut-brain axis in autism.Antioxidants reverse the changes in energy metabolism of rat brain after chronic administration of L.-tyrosine.Neurotoxins as Preclinical Models for Parkinson's Disease.Omega-3 Fatty Acids and Mood Stabilizers Alter Behavioural and Energy Metabolism Parameters in Animals Subjected to an Animal Model of Mania Induced by Fenproporex.Aminochrome Induces Irreversible Mitochondrial Dysfunction by Inducing Autophagy Dysfunction in Parkinson's Disease.
P2860
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P2860
The dopamine metabolite aminochrome inhibits mitochondrial complex I and modifies the expression of iron transporters DMT1 and FPN1.
description
2012 nî lūn-bûn
@nan
2012年の論文
@ja
2012年論文
@yue
2012年論文
@zh-hant
2012年論文
@zh-hk
2012年論文
@zh-mo
2012年論文
@zh-tw
2012年论文
@wuu
2012年论文
@zh
2012年论文
@zh-cn
name
The dopamine metabolite aminoc ...... on transporters DMT1 and FPN1.
@en
The dopamine metabolite aminoc ...... on transporters DMT1 and FPN1.
@nl
type
label
The dopamine metabolite aminoc ...... on transporters DMT1 and FPN1.
@en
The dopamine metabolite aminoc ...... on transporters DMT1 and FPN1.
@nl
prefLabel
The dopamine metabolite aminoc ...... on transporters DMT1 and FPN1.
@en
The dopamine metabolite aminoc ...... on transporters DMT1 and FPN1.
@nl
P2093
P2860
P50
P1433
P1476
The dopamine metabolite aminoc ...... ron transporters DMT1 and FPN1
@en
P2093
Monica Villa
Pabla Aguirre
Pamela Urrutia
Victoria Tapia
P2860
P2888
P304
P356
10.1007/S10534-012-9525-Y
P577
2012-08-01T00:00:00Z