MdmX is required for p53 interaction with and full induction of the Mdm2 promoter after cellular stress. - Wikidata - wikimedia - TriplyDB

MdmX is required for p53 interaction with and full induction of the Mdm2 promoter after cellular stress.

MdmX is required for p53 interaction with and full induction of the Mdm2 promoter after cellular stress.

http://www.wikidata.org/entity/Q39404029

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Deubiquitinating enzyme regulation of the p53 pathway: A lesson from Otub1 Glioblastoma cells inhibit astrocytic p53-expression favoring cancer malignancy Doxorubicin and 5-fluorouracil induced accumulation and transcriptional activity of p53 are independent of the phosphorylation at serine 15 in MCF-7 breast cancer cells Ribosomal proteins RPL37, RPS15 and RPS20 regulate the Mdm2-p53-MdmX network p53 Regulation Goes Live-Mdm2 and MdmX Co-Star: Lessons Learned from Mouse Modeling.Targeting RING domains of Mdm2-MdmX E3 complex activates apoptotic arm of the p53 pathway in leukemia/lymphoma cells Loci influencing blood pressure identified using a cardiovascular gene-centric array.Estrogen receptor alpha (ERα/ESR1) mediates the p53-independent overexpression of MDM4/MDMX and MDM2 in human breast cancer.The regulation of MDM2 oncogene and its impact on human cancers.Mdm2 and MdmX as Regulators of Gene Expression Targeting p53-MDM2-MDMX loop for cancer therapy.Cisplatin causes cell death via TAB1 regulation of p53/MDM2/MDMX circuitry.Protecting the genome from mdm2 and mdmx.Evaluation of TP53 Pro72Arg and MDM2 SNP285-SNP309 polymorphisms in an Italian cohort of LFS suggestive patients lacking identifiable TP53 germline mutations.

P2860

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P2860

MdmX is required for p53 interaction with and full induction of the Mdm2 promoter after cellular stress.

http://www.wikidata.org/entity/Q39404029

description

2012 nî lūn-bûn

@nan

2012年の論文

@ja

2012年論文

@yue

2012年論文

@zh-hant

2012年論文

@zh-hk

2012年論文

@zh-mo

2012年論文

@zh-tw

2012年论文

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2012年论文

@zh

2012年论文

@zh-cn

name

MdmX is required for p53 inter ...... romoter after cellular stress.

@en

MdmX is required for p53 inter ...... romoter after cellular stress.

@nl

type

label

MdmX is required for p53 inter ...... romoter after cellular stress.

@en

MdmX is required for p53 inter ...... romoter after cellular stress.

@nl

prefLabel

MdmX is required for p53 inter ...... romoter after cellular stress.

@en

MdmX is required for p53 inter ...... romoter after cellular stress.

@nl

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P1433

Molecular and Cellular Biology

P1476

MdmX is required for p53 inter ...... romoter after cellular stress.

@en

P2093

Carol Prives

http://www.w3.org/2001/XMLSchema#string

Lynn Biderman

http://www.w3.org/2001/XMLSchema#string

Masha V Poyurovsky

http://www.w3.org/2001/XMLSchema#string

Yael Assia

http://www.w3.org/2001/XMLSchema#string

P2860

ASPP proteins specifically stimulate the apoptotic function of p53

The Wip1 Phosphatase acts as a gatekeeper in the p53-Mdm2 autoregulatory loop

The activity of p53 is differentially regulated by Brm- and Brg1-containing SWI/SNF chromatin remodeling complexes

Mdm4 (Mdmx) regulates p53-induced growth arrest and neuronal cell death during early embryonic mouse development.

14-3-3gamma binds to MDMX that is phosphorylated by UV-activated Chk1, resulting in p53 activation

Mdmx enhances p53 ubiquitination by altering the substrate preference of the Mdm2 ubiquitin ligase

Mdm2 promotes the rapid degradation of p53

Oncoprotein MDM2 is a ubiquitin ligase E3 for tumor suppressor p53

Wip1, a novel human protein phosphatase that is induced in response to ionizing radiation in a p53-dependent manner

DNA damage-induced phosphorylation of MdmX at serine 367 activates p53 by targeting MdmX for Mdm2-dependent degradation.

P304

1214-1225

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scholarly article

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10.1128/MCB.06150-11

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7

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32

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James L. Manley

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2012-01-30T00:00:00Z

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221791868

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22290440

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3302446

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