Metformin inhibits growth of thyroid carcinoma cells, suppresses self-renewal of derived cancer stem cells, and potentiates the effect of chemotherapeutic agents.
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Metformin and thyroid: an updateThe links between insulin resistance, diabetes, and cancerThyroid tumor-initiating cells: increasing evidence and opportunities for anticancer therapy (review)Metformin as an adjuvant drug against pediatric sarcomas: hypoxia limits therapeutic effects of the drugThe anti-diabetic drug metformin protects against chemotherapy-induced peripheral neuropathy in a mouse modelEffects of prolonged exposure to low dose metformin in thyroid cancer cell lines.Metformin reduces thyroid cancer risk in Taiwanese patients with type 2 diabetes.Metformin repositioning as antitumoral agent: selective antiproliferative effects in human glioblastoma stem cells, via inhibition of CLIC1-mediated ion currentSorafenib synergizes with metformin in NSCLC through AMPK pathway activation.Expression of cancer stem cell markers and epithelial-mesenchymal transition-related factors in anaplastic thyroid carcinoma.In vitro and in vivo antiproliferative activity of metformin on stem-like cells isolated from spontaneous canine mammary carcinomas: translational implications for human tumorsA novel dual AMPK activator/mTOR inhibitor inhibits thyroid cancer cell growthNo evidence for a decreased risk of thyroid cancer in association with use of metformin or other antidiabetic drugs: a case-control study.Metformin induces ER stress-dependent apoptosis through miR-708-5p/NNAT pathway in prostate cancerDiabetes and thyroid cancer risk: literature review.The insulin and igf-I pathway in endocrine glands carcinogenesisMetformin Is Associated with a Favorable Outcome in Diabetic Patients with Cervical Lymph Node Metastasis of Differentiated Thyroid CancerTMP21 modulates cell growth in papillary thyroid cancer cells by inducing autophagy through activation of the AMPK/mTOR pathway.Metformin and its clinical use: new insights for an old drug in clinical practice.Metformin: Midlife maturity, maiden charmmTOR inhibitors sensitize thyroid cancer cells to cytotoxic effect of vemurafenibMetformin selectively affects human glioblastoma tumor-initiating cell viability: A role for metformin-induced inhibition of Akt.Diabetes, Diabetes Treatment, and Risk of Thyroid Cancer.The Relationship between Type 2 Diabetes Mellitus and Related Thyroid Diseases.Metformin blocks progression of obesity-activated thyroid cancer in a mouse model.Altered gene products involved in the malignant reprogramming of cancer stem/progenitor cells and multitargeted therapies.Perspectives of the AMP-activated kinase (AMPK) signalling pathway in thyroid cancer.Cancer outcomes and all-cause mortality in adults allocated to metformin: systematic review and collaborative meta-analysis of randomised clinical trials.Stem cells and cancer stem-like cells in endocrine tissues.Repositioning metformin in cancer: genetics, drug targets, and new ways of delivery.Cancer stem cells: biological functions and therapeutically targeting.Emerging strategies for managing differentiated thyroid cancers refractory to radioiodine.Effect of Interferon-γ on the Basal and the TNFα-Stimulated Secretion of CXCL8 in Thyroid Cancer Cell Lines Bearing Either the RET/PTC Rearrangement Or the BRAF V600e Mutation.1,25 dihydroxyvitamin D3 inhibits the proliferation of thyroid cancer stem-like cells via cell cycle arrest.Glucose-deprivation increases thyroid cancer cells sensitivity to metformin.Inositol(s) in thyroid function, growth and autoimmunity.Metformin and salinomycin as the best combination for the eradication of NSCLC monolayer cells and their alveospheres (cancer stem cells) irrespective of EGFR, KRAS, EML4/ALK and LKB1 status.Metformin is synthetically lethal with glucose withdrawal in cancer cells.The Association between Type 2 Diabetes Mellitus and Thyroid Cancer.Preventive effect of Metformin against N-nitrosodiethylamine-initiated hepatocellular carcinoma in rats.
P2860
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P2860
Metformin inhibits growth of thyroid carcinoma cells, suppresses self-renewal of derived cancer stem cells, and potentiates the effect of chemotherapeutic agents.
description
2012 nî lūn-bûn
@nan
2012年の論文
@ja
2012年論文
@yue
2012年論文
@zh-hant
2012年論文
@zh-hk
2012年論文
@zh-mo
2012年論文
@zh-tw
2012年论文
@wuu
2012年论文
@zh
2012年论文
@zh-cn
name
Metformin inhibits growth of t ...... ct of chemotherapeutic agents.
@en
Metformin inhibits growth of t ...... ct of chemotherapeutic agents.
@nl
type
label
Metformin inhibits growth of t ...... ct of chemotherapeutic agents.
@en
Metformin inhibits growth of t ...... ct of chemotherapeutic agents.
@nl
prefLabel
Metformin inhibits growth of t ...... ct of chemotherapeutic agents.
@en
Metformin inhibits growth of t ...... ct of chemotherapeutic agents.
@nl
P2093
P356
P1476
Metformin inhibits growth of t ...... ct of chemotherapeutic agents.
@en
P2093
Guofang Chen
Kostja Renko
Michael Derwahl
Shuhang Xu
P304
P356
10.1210/JC.2011-1754
P407
P577
2012-01-25T00:00:00Z