Enforced viral replication activates adaptive immunity and is essential for the control of a cytopathic virus.
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Harnessing Mechanistic Knowledge on Beneficial Versus Deleterious IFN-I Effects to Design Innovative Immunotherapies Targeting Cytokine Activity to Specific Cell TypesTissue-resident macrophagesThe Lymphotoxin Network: orchestrating a type I interferon response to optimize adaptive immunitySubcapsular sinus macrophage fragmentation and CD169+ bleb acquisition by closely associated IL-17-committed innate-like lymphocytesThe regulation of T follicular helper responses during infectionProtective Capacity of the Human Anamnestic Antibody Response during Acute Dengue Virus InfectionThe mannose receptorHigh efficiency cell-specific targeting of cytokine activityCytokine Activation by Antibody Fragments Targeted to Cytokine-Receptor Signaling Complexes.Peripheral prepositioning and local CXCL9 chemokine-mediated guidance orchestrate rapid memory CD8+ T cell responses in the lymph node.Neurovirulence and immunogenicity of attenuated recombinant vesicular stomatitis viruses in nonhuman primates.USP18 is crucial for IFN-γ-mediated inhibition of B16 melanoma tumorigenesis and antitumor immunity.A systemic macrophage response is required to contain a peripheral poxvirus infectionEfficient transduction of myeloid cells by an HIV-1-derived lentiviral vector that packages the Vpx accessory proteinPoly(I:C) treatment leads to interferon-dependent clearance of hepatitis B virus in a hydrodynamic injection mouse model.Selective inactivation of USP18 isopeptidase activity in vivo enhances ISG15 conjugation and viral resistanceLipid nanoparticle siRNA treatment of Ebola-virus-Makona-infected nonhuman primates.Lymphotoxin-LIGHT pathway regulates the interferon signature in rheumatoid arthritis.Usp18 driven enforced viral replication in dendritic cells contributes to break of immunological tolerance in autoimmune diabetes.CEACAM1 induces B-cell survival and is essential for protective antiviral antibody productionTumor necrosis factor superfamily in innate immunity and inflammation.Deficiency of the B cell-activating factor receptor results in limited CD169+ macrophage function during viral infectionCD169+ macrophages are sufficient for priming of CTLs with specificities left out by cross-priming dendritic cells.Much More than M1 and M2 Macrophages, There are also CD169(+) and TCR(+) Macrophages.Lymph Node Macrophages Restrict Murine Cytomegalovirus DisseminationAntiviral Protection via RdRP-Mediated Stable Activation of Innate Immunity.Stat1-Deficient Mice Are Not an Appropriate Model for Efficacy Testing of Recombinant Vesicular Stomatitis Virus-Based Filovirus VaccinesType 1 Interferons and NK Cells Limit Murine Cytomegalovirus Escape from the Lymph Node Subcapsular Sinus.Global survey of the immunomodulatory potential of common drugs.Subcapsular sinus macrophages limit acute gammaherpesvirus disseminationVirus-specific antibodies allow viral replication in the marginal zone, thereby promoting CD8(+) T-cell priming and viral controlType I interferons in viral control and immune regulationLymphotoxin network pathways shape the tumor microenvironmentLymphoid-tissue stromal cells coordinate innate defense to cytomegalovirus.Lipopolysaccharide and Tumor Necrosis Factor Alpha Inhibit Interferon Signaling in Hepatocytes by Increasing Ubiquitin-Like Protease 18 (USP18) Expression.Rapid early innate control of hepatitis C virus during IFN-α treatment compromises adaptive CD4+ T-cell immunity.Type I Interferons and NK Cells Restrict Gammaherpesvirus Lymph Node Infection.Immunoactivation induced by chronic viral infection inhibits viral replication and drives immunosuppression through sustained IFN-I responses.CD169+ macrophages regulate PD-L1 expression via type I interferon and thereby prevent severe immunopathology after LCMV infection.Presentation of Autoantigen in Peripheral Lymph Nodes Is Sufficient for Priming Autoreactive CD8+ T Cells.
P2860
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P2860
Enforced viral replication activates adaptive immunity and is essential for the control of a cytopathic virus.
description
2011 nî lūn-bûn
@nan
2011年の論文
@ja
2011年学术文章
@wuu
2011年学术文章
@zh-cn
2011年学术文章
@zh-hans
2011年学术文章
@zh-my
2011年学术文章
@zh-sg
2011年學術文章
@yue
2011年學術文章
@zh
2011年學術文章
@zh-hant
name
Enforced viral replication act ...... control of a cytopathic virus.
@en
Enforced viral replication act ...... control of a cytopathic virus.
@nl
type
label
Enforced viral replication act ...... control of a cytopathic virus.
@en
Enforced viral replication act ...... control of a cytopathic virus.
@nl
prefLabel
Enforced viral replication act ...... control of a cytopathic virus.
@en
Enforced viral replication act ...... control of a cytopathic virus.
@nl
P2093
P2860
P50
P356
P1433
P1476
Enforced viral replication act ...... control of a cytopathic virus.
@en
P2093
Christoph Burkart
Dong-Er Zhang
Giuseppe Cadeddu
Hartmut Hengel
Karl S Lang
Masato Tanaka
Max Löhning
Melanie Grusdat
Mike Recher
Nadine Honke
P2860
P356
10.1038/NI.2169
P407
P50
P577
2011-11-20T00:00:00Z