Human embryonic stem cell derived astrocytes mediate non-cell-autonomous neuroprotection through endogenous and drug-induced mechanisms.
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Human Stem Cell-Derived Astrocytes: Specification and Relevance for Neurological DisordersQuo vadis motor neuron disease?Neuronal development is promoted by weakened intrinsic antioxidant defences due to epigenetic repression of Nrf2Neurons and neuronal activity control gene expression in astrocytes to regulate their development and metabolism.Phosphoinositide 3-kinases upregulate system xc(-) via eukaryotic initiation factor 2α and activating transcription factor 4 - A pathway active in glioblastomas and epilepsyProgressive Motor Neuron Pathology and the Role of Astrocytes in a Human Stem Cell Model of VCP-Related ALSRole of astroglia in Down's syndrome revealed by patient-derived human-induced pluripotent stem cells.Stem cells on the brain: modeling neurodevelopmental and neurodegenerative diseases using human induced pluripotent stem cells.Attenuation of Cerebral Ischemic Injury in Smad1 Deficient Mice.Expression of mRNA Encoding Mcu and Other Mitochondrial Calcium Regulatory Genes Depends on Cell Type, Neuronal Subtype, and Ca2+ SignalingAstrocytes and disease: a neurodevelopmental perspectiveSelective dendritic susceptibility to bioenergetic, excitotoxic and redox perturbations in cortical neurons.Synthetic oleanane triterpenoids: multifunctional drugs with a broad range of applications for prevention and treatment of chronic disease.Experimental and therapeutic opportunities for stem cells in multiple sclerosisA cellular star atlas: using astrocytes from human pluripotent stem cells for disease studiesDecreased zinc availability affects glutathione metabolism in neuronal cells and in the developing brain.NMDA receptor-dependent glutamate excitotoxicity in human embryonic stem cell-derived neuronsEvidence for evolutionary divergence of activity-dependent gene expression in developing neuronshESC-derived Olig2+ progenitors generate a subtype of astroglia with protective effects against ischaemic brain injury.Human stem cell-derived astrocytes and their application to studying Nrf2-mediated neuroprotective pathways and therapeutics in neurodegenerationA plethora of human pluripotent stem cells.In vitro neurogenesis: development and functional implications of iPSC technology.ASTROCYTES: EMERGING STARS IN LEUKODYSTROPHY PATHOGENESIS.Glutathione-Dependent Detoxification Processes in Astrocytes.Experimental Advances Towards Neural Regeneration from Induced Stem Cells to Direct In Vivo Reprogramming.Stem and Progenitor Cell-Derived Astroglia Therapies for Neurological Diseases.Stem cell-derived astrocytes: are they physiologically credible?Switching from astrocytic neuroprotection to neurodegeneration by cytokine stimulation.Neural Subtype Specification from Human Pluripotent Stem Cells.Synaptic NMDA receptor activity is coupled to the transcriptional control of the glutathione system.Functional and phenotypic differences of pure populations of stem cell-derived astrocytes and neuronal precursor cells.Microglial Janus kinase/signal transduction and activator of transcription 3 pathway activity directly impacts astrocyte and spinal neuron characteristics.Parkinsonian toxin-induced oxidative stress inhibits basal autophagy in astrocytes via NQO2/quinone oxidoreductase 2: Implications for neuroprotection.Unpicking neurodegeneration in a dish with human pluripotent stem cells: one cell type at a time.Concise Review: The Cellular Conspiracy of Amyotrophic Lateral Sclerosis.Human iPS-Derived Astroglia from a Stable Neural Precursor State Show Improved Functionality Compared with Conventional Astrocytic Models.From the Cover: AstrocytesAre Protective Against Chlorpyrifos Developmental Neurotoxicity in Human Pluripotent Stem Cell-Derived Astrocyte-Neuron Cocultures.Astrocytes in a dish: Using pluripotent stem cells to model neurodegenerative and neurodevelopmental disorders.
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P2860
Human embryonic stem cell derived astrocytes mediate non-cell-autonomous neuroprotection through endogenous and drug-induced mechanisms.
description
2011 nî lūn-bûn
@nan
2011年の論文
@ja
2011年学术文章
@wuu
2011年学术文章
@zh-cn
2011年学术文章
@zh-hans
2011年学术文章
@zh-my
2011年学术文章
@zh-sg
2011年學術文章
@yue
2011年學術文章
@zh
2011年學術文章
@zh-hant
name
Human embryonic stem cell deri ...... s and drug-induced mechanisms.
@en
Human embryonic stem cell deri ...... s and drug-induced mechanisms.
@nl
type
label
Human embryonic stem cell deri ...... s and drug-induced mechanisms.
@en
Human embryonic stem cell deri ...... s and drug-induced mechanisms.
@nl
prefLabel
Human embryonic stem cell deri ...... s and drug-induced mechanisms.
@en
Human embryonic stem cell deri ...... s and drug-induced mechanisms.
@nl
P2093
P2860
P50
P356
P1476
Human embryonic stem cell deri ...... us and drug-induced mechanisms
@en
P2093
P2860
P2888
P304
P356
10.1038/CDD.2011.154
P577
2011-11-18T00:00:00Z