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Human embryonic stem cell-derived neurons as a tool for studying neuroprotection and neurodegenerationHuman Stem Cell-Derived Astrocytes: Specification and Relevance for Neurological DisordersNeural Conversion and Patterning of Human Pluripotent Stem Cells: A Developmental PerspectiveQuo vadis motor neuron disease?Generating Diverse Spinal Motor Neuron Subtypes from Human Pluripotent Stem CellsActivin/Nodal inhibition alone accelerates highly efficient neural conversion from human embryonic stem cells and imposes a caudal positional identity.Human stem cell-derived neurons: a system to study human tau function and dysfunctionProgressive Motor Neuron Pathology and the Role of Astrocytes in a Human Stem Cell Model of VCP-Related ALSThe mesenchymal stem cells in multiple sclerosis (MSCIMS) trial protocol and baseline cohort characteristics: an open-label pre-test: post-test study with blinded outcome assessmentsRetinoid-independent motor neurogenesis from human embryonic stem cells reveals a medial columnar ground state.Autologous mesenchymal stem cells for the treatment of secondary progressive multiple sclerosis: an open-label phase 2a proof-of-concept study.Hypothermic Preconditioning of Human Cortical Neurons Requires Proteostatic PrimingUsing human induced pluripotent stem cells to model cerebellar disease: hope and hype.Investigating the utility of human embryonic stem cell-derived neurons to model ageing and neurodegenerative disease using whole-genome gene expression and splicing analysis.Experimental and therapeutic opportunities for stem cells in multiple sclerosisHypothermic Preconditioning Reverses Tau Ontogenesis in Human Cortical Neurons and is Mimicked by Protein Phosphatase 2A Inhibition.Evidence for evolutionary divergence of activity-dependent gene expression in developing neuronsIn vitro prion-like behaviour of TDP-43 in ALS.The translational potential of human induced pluripotent stem cells for clinical neurology : The translational potential of hiPSCs in neurology.Stem cells as a resource for regenerative neurology.Using induced pluripotent stem cells (iPSC) to model human neuromuscular connectivity: promise or reality?Using human pluripotent stem cells to study post-transcriptional mechanisms of neurodegenerative diseases.Human embryonic stem cell derived astrocytes mediate non-cell-autonomous neuroprotection through endogenous and drug-induced mechanisms.Characterizing the RNA targets and position-dependent splicing regulation by TDP-43.Major Shifts in Glial Regional Identity Are a Transcriptional Hallmark of Human Brain Aging.Mild oxidative stress activates Nrf2 in astrocytes, which contributes to neuroprotective ischemic preconditioning.A neuroprotective astrocyte state is induced by neuronal signal EphB1 but fails in ALS models.Integrin activation promotes axon growth on inhibitory chondroitin sulfate proteoglycans by enhancing integrin signaling.Lymphomatosis cerebri: a treatable cause of rapidly progressive dementia.Dopamine from the brain promotes spinal motor neuron generation during development and adult regeneration.Concise Review: The Cellular Conspiracy of Amyotrophic Lateral Sclerosis.G-quadruplex-binding small molecules ameliorate C9orf72 FTD/ALS pathology in vitro and in vivo.Elucidating Pro-Inflammatory Cytokine Responses after Traumatic Brain Injury in a Human Stem Cell Model.TS or not TS?Abnormal tau phosphorylation in primary progressive multiple sclerosis.Evidence for abnormal tau phosphorylation in early aggressive multiple sclerosis.Three-Dimensional Human iPSC-Derived Artificial Skeletal Muscles Model Muscular Dystrophies and Enable Multilineage Tissue Engineering.A Liquid to Solid Phase Transition Underlying Pathological Huntingtin Exon1 Aggregation.Kir4.1-Dependent Astrocyte-Fast Motor Neuron Interactions Are Required for Peak Strength.Intron retention and nuclear loss of SFPQ are molecular hallmarks of ALS.
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wetenschapper
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հետազոտող
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Rickie Patani
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Rickie Patani
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Rickie Patani
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Rickie Patani
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Rickie Patani
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Rickie Patani
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Rickie Patani
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Rickie Patani
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Rickie Patani
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Rickie Patani
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Rickie Patani
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Rickie Patani
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Rickie Patani
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Rickie Patani
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Rickie Patani
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P106
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P496
0000-0002-3825-7675