Design of conditionally active STATs: insights into STAT activation and gene regulatory function.
about
Distinct roles of the NH2- and COOH-terminal domains of the protein inhibitor of activated signal transducer and activator of transcription (STAT) 1 (PIAS1) in cytokine-induced PIAS1-Stat1 interactionNucleocytoplasmic shuttling of endocytic proteinsPrinciples of interleukin (IL)-6-type cytokine signalling and its regulationPhosphorylation-induced dimerization of interferon regulatory factor 7 unmasks DNA binding and a bipartite transactivation domainArginine/lysine-rich nuclear localization signals mediate interactions between dimeric STATs and importin alpha 5Inhibition of STAT3 signaling leads to apoptosis of leukemic large granular lymphocytes and decreased Mcl-1 expressionA completely foreign receptor can mediate an interferon-gamma-like response.A novel sequence in the coiled-coil domain of Stat3 essential for its nuclear translocationConversion of threonine 757 to valine enhances Stat5a transactivation potentialArginine/lysine-rich structural element is involved in interferon-induced nuclear import of STATs.Cell nucleus in contextSerine phosphorylation of STATs.Regulated nuclear import of the STAT1 transcription factor by direct binding of importin-alphaElucidating the crosstalk mechanism between IFN-gamma and IL-6 via mathematical modelling.Nuclear export signal located within theDNA-binding domain of the STAT1transcription factor.The ins and outs of STAT1 nuclear transport.DNA binding controls inactivation and nuclear accumulation of the transcription factor Stat1.Effects of insulin and IGF-I on growth hormone- induced STAT5 activation in 3T3-F442A adipocytesTEL/ETV6 is a signal transducer and activator of transcription 3 (Stat3)-induced repressor of Stat3 activity.Crosstalk between STAT5 activation and PI3K/AKT functions in normal and transformed mammary epithelial cells.Importin alpha nuclear localization signal binding sites for STAT1, STAT2, and influenza A virus nucleoprotein.Insulin antagonizes interleukin-6 signaling and is anti-inflammatory in 3T3-L1 adipocytes.Pyrrolidine Dithiocarbamate Inhibits Interleukin-6 Signaling through Impaired STAT3 Activation and Association with Transcriptional Coactivators in Hepatocytes
P2860
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P2860
Design of conditionally active STATs: insights into STAT activation and gene regulatory function.
description
1999 nî lūn-bûn
@nan
1999年の論文
@ja
1999年学术文章
@wuu
1999年学术文章
@zh-cn
1999年学术文章
@zh-hans
1999年学术文章
@zh-my
1999年学术文章
@zh-sg
1999年學術文章
@yue
1999年學術文章
@zh
1999年學術文章
@zh-hant
name
Design of conditionally active ...... and gene regulatory function.
@en
Design of conditionally active ...... and gene regulatory function.
@nl
type
label
Design of conditionally active ...... and gene regulatory function.
@en
Design of conditionally active ...... and gene regulatory function.
@nl
prefLabel
Design of conditionally active ...... and gene regulatory function.
@en
Design of conditionally active ...... and gene regulatory function.
@nl
P2093
P2860
P356
P1476
Design of conditionally active ...... and gene regulatory function.
@en
P2093
P2860
P304
P356
10.1128/MCB.19.4.2913
P407
P577
1999-04-01T00:00:00Z