Anti-proliferative effect of curcumin on melanoma cells is mediated by PDE1A inhibition that regulates the epigenetic integrator UHRF1. - Wikidata - wikimedia - TriplyDB

Anti-proliferative effect of curcumin on melanoma cells is mediated by PDE1A inhibition that regulates the epigenetic integrator UHRF1.

Anti-proliferative effect of curcumin on melanoma cells is mediated by PDE1A inhibition that regulates the epigenetic integrator UHRF1.

http://www.wikidata.org/entity/Q39449331

about

The Potential of Plant Phenolics in Prevention and Therapy of Skin Disorders Therapeutic targeting of replicative immortality Unraveling the Anticancer Effect of Curcumin and Resveratrol Signalling pathways in UHRF1-dependent regulation of tumor suppressor genes in cancer Delphinidin Inhibits Tumor Growth by Acting on VEGF Signalling in Endothelial Cells Resveratrol and curcumin enhance pancreatic β-cell function by inhibiting phosphodiesterase activity.The curcumin analog DM-1 induces apoptotic cell death in melanoma.DNA Methylation and Flavonoids in Genitourinary Cancers.Phosphodiesterase sequence variants may predispose to prostate cancer.Phytochemical antioxidants modulate mammalian cellular epigenome: implications in health and disease.Targeting drivers of melanoma with synthetic small molecules and phytochemicals.Digging deep into "dirty" drugs - modulation of the methylation machinery.Limoniastrum guyonianum aqueous gall extract induces apoptosis in human cervical cancer cells involving p16 INK4A re-expression related to UHRF1 and DNMT1 down-regulation.Combination of low concentration of (-)-epigallocatechin gallate (EGCG) and curcumin strongly suppresses the growth of non-small cell lung cancer in vitro and in vivo through causing cell cycle arrest.Design, characterization, and biological evaluation of curcumin-loaded surfactant-based systems for topical drug delivery.Molecular mechanisms of hypolipidemic effects of curcumin.Curcumin as a regulator of epigenetic events.Bioinformatics analysis to identify the differentially expressed genes of glaucoma Modulation of cAMP levels by high-fat diet and curcumin and regulatory effects on CD36/FAT scavenger receptor/fatty acids transporter gene expression.Curcumin: A new candidate for melanoma therapy?Promoter methylation-independent reactivation of PAX1 by curcumin and resveratrol is mediated by UHRF1.Evaluation of phenolic profile, antioxidant and anticancer potential of two main representants of Zingiberaceae family against B164A5 murine melanoma cells.Luteolin induces apoptosis in BE colorectal cancer cells by downregulating calpain, UHRF1, and DNMT1 expressions.Chemopreventive effects of curcumin on chemically induced mouse skin carcinogenesis in BK5.insulin-like growth factor-1 transgenic mice.Limoniastrum guyonianum aqueous gall extract induces apoptosis in colorectal cancer cells by inhibiting calpain activity.Curcumin inhibits human retinal pigment epithelial cell proliferation Phosphodiesterase 4 regulates the migration of B16-F10 melanoma cells.Dose-dependent bioavailability indicators for curcumin and two of its novel derivatives.Curcumin and Melanoma: From Chemistry to Medicine.Bcl-2 family proteins and cytoskeleton changes involved in DM-1 cytotoxic effect on melanoma cells.New cGMP analogues restrain proliferation and migration of melanoma cells.Epigenetic modulation of DNA methylation by nutrition and its mechanisms in animals.Targeting the SET and RING-associated (SRA) domain of ubiquitin-like, PHD and ring finger-containing 1 (UHRF1) for anti-cancer drug development.Epigenetics, Plant (Poly)phenolics, and Cancer Prevention Xyloglucan-block-Poly(ϵ-Caprolactone) Copolymer Nanoparticles Coated with Chitosan as Biocompatible Mucoadhesive Drug Delivery System Flavonoids and Other Phenolic Compounds from Medicinal Plants for Pharmaceutical and Medical Aspects: An Overview

P2860

Q26768462-3D8DC0D5-8646-4046-9A01-895323E19C01 Q27027457-AB041D2F-41AE-4B2A-84D7-ACD11AEA1D6B Q28073155-ACA25CE6-12DA-4735-A8D3-D7AA31515B0A Q28073257-C5C4DC5C-7AA5-4231-A226-EF4D1BB2F3E2 Q28551689-124AEF12-0BB3-40EF-A316-0AEB567D488B Q34312189-824B6B75-FC92-470B-B345-D350EF817B20 Q34566244-8FD04D12-94A5-41B6-88F1-8EFCD7FA25CC Q35623184-CCE32177-D2F8-4218-94A0-DB61798EA5AC Q35843428-24B56BFC-ED7C-47B3-AB9B-E1C326280A58 Q35965132-6DD204DB-80B2-4DA9-9C25-6D583E8EAF95 Q36141097-0A1C4B15-9610-4C69-93DB-DFB218660B61 Q36523796-ACBD8ACA-C98A-42F1-94D4-990BFA15A93F Q36964305-250C691D-92D3-4355-B948-A1BE81E1304E Q37007277-6A4D3DFE-57DA-4932-9638-F886BB062BCB Q37249022-EF5B65D7-2796-41CB-A6C8-116C07F6C8FE Q38075862-79D61F82-09BD-48D1-939F-FFD244C45536 Q38113525-563C8B56-D120-4661-99AE-508F4966DF12 Q38461206-A5E22995-9F0C-4E01-AE5D-0435753FB242 Q38760996-E3BEA02F-16A8-41B4-8CA0-2C131C949737 Q38859978-F4752D27-5829-42CC-83EF-DEC282AC8954 Q38863180-458B6865-DB4F-4965-8C59-C4526E899827 Q38912697-0B7B5BFC-44E9-463D-B3E8-6998E771E08D Q38957808-8D4CB780-AF4F-4508-9FB1-C292B44CDBA5 Q38975030-88C1C496-9301-4C91-9ACB-8F17ACE33928 Q38995013-6CFCB4F3-77D5-4BC0-A29D-34AB3152E2C6 Q41848097-570323A8-0598-4E91-AEDA-564855BCF709 Q42324596-0EB5A619-0D7B-45B3-AFAF-D5B863598303 Q46542212-76DF556C-E2DD-42FB-BF91-3D991DF53D7E Q47210956-049F2034-FD1C-4730-A4B4-B084DE3EAEF2 Q49016130-B976FC04-F181-4047-A6B3-DB246AC72357 Q49723790-D4828DFF-0115-47F8-9636-BEC19C323871 Q55020285-AD8DA962-56D3-48D5-BD28-FE76967B1E31 Q55129550-B3DC8911-DFD8-4384-86B1-3032FF8D4D62 Q57782660-A5FDE395-2D32-405B-B6D3-B7EDDB2A2DC6 Q58063468-8FEF1894-9A5D-4CC1-A679-C48F0C83AF24 Q58702473-7CC969A3-078E-4D86-BF47-1232CA0555AF

P2860

Anti-proliferative effect of curcumin on melanoma cells is mediated by PDE1A inhibition that regulates the epigenetic integrator UHRF1.

http://www.wikidata.org/entity/Q39449331

description

2011 nî lūn-bûn

@nan

2011年の論文

@ja

2011年学术文章

@wuu

2011年学术文章

@zh-cn

2011年学术文章

@zh-hans

2011年学术文章

@zh-my

2011年学术文章

@zh-sg

2011年學術文章

@yue

2011年學術文章

@zh

2011年學術文章

@zh-hant

name

Anti-proliferative effect of c ...... e epigenetic integrator UHRF1.

@en

Anti-proliferative effect of c ...... e epigenetic integrator UHRF1.

@nl

type

label

Anti-proliferative effect of c ...... e epigenetic integrator UHRF1.

@en

Anti-proliferative effect of c ...... e epigenetic integrator UHRF1.

@nl

prefLabel

Anti-proliferative effect of c ...... e epigenetic integrator UHRF1.

@en

Anti-proliferative effect of c ...... e epigenetic integrator UHRF1.

@nl

P1433

Q39449331-87698C49-34E2-4655-AC96-05499519F573

P1476

Q39449331-76C413A1-9B48-4C4A-95A2-C51E2F03718D

P2093

Q39449331-5AB60016-C05E-40AE-8AED-DCCEB3C3E474

Q39449331-7BC7AAF0-235C-4228-8611-F1FA7C14739A

Q39449331-8E9F43AF-4614-4E6E-B8A5-6BF32B24D6E1

Q39449331-C3D90868-D4CF-4D44-A937-5C3A03B041B3

P2860

Q39449331-07ABA923-DDE2-44BF-87FF-416277B0653C

Q39449331-09CB69D9-AB02-49CC-A6A1-EB6B385B622F

Q39449331-0D64D789-99A6-4E18-ABBB-ABED711ED166

Q39449331-1048A828-CD18-4EFA-88AB-03663E91251C

Q39449331-1460619C-80BB-451E-BC59-DA8D2AA0BC96

Q39449331-192C10D1-06ED-4BB3-A009-62894217BF79

Q39449331-1C9B798C-9689-4447-A901-BD9893DA1803

Q39449331-216B1DED-5512-4B73-8F9C-9BED8915105F

Q39449331-26B577BA-7E83-4109-BA87-88665DE2E144

Q39449331-3139A494-2812-4BB5-9FAB-6589FD78799D

P304

Q39449331-D2C8F047-3AA3-4B3D-80C9-87CB3BB0FEF3

P31

Q39449331-07F1EFF1-E7B8-4254-81EA-EF7C7E2F89DD

P356

Q39449331-8FCF0426-D56B-49A8-9DD2-2ABD28AEB201

P433

Q39449331-FB51F8FE-51E4-491E-857E-7A068265806D

P478

Q39449331-B250EE1F-B11E-447B-8075-561A341E1D9B

P50

Q39449331-9CA71ACC-9D0F-483D-8189-4B471FF40BDD

P577

Q39449331-55E174E0-52F8-4856-AFA0-65082460E88A

P698

Q39449331-D824DE46-21C9-47ED-AF9A-817D199534ED

P921

Q39449331-297459a6-d485-452b-873b-282f5b01d634

P356

P1433

Molecular Nutrition and Food Research

P1476

Anti-proliferative effect of c ...... he epigenetic integrator UHRF1

@en

P2093

Abdurazzag Abusnina

http://www.w3.org/2001/XMLSchema#string

Claire Lugnier

http://www.w3.org/2001/XMLSchema#string

Issaka Yougbaré

http://www.w3.org/2001/XMLSchema#string

Thérèse Keravis

http://www.w3.org/2001/XMLSchema#string

P2860

The interaction of the SRA domain of ICBP90 with a novel domain of DNMT1 is involved in the regulation of VEGF gene expression

ICBP90, an E2F-1 target, recruits HDAC1 and binds to methyl-CpG through its SRA domain

ICBP90 belongs to a new family of proteins with an expression that is deregulated in cancer cells

Analysis of Relative Gene Expression Data Using Real-Time Quantitative PCR and the 2−ΔΔCT Method

The SRA domain of UHRF1 flips 5-methylcytosine out of the DNA helix

Structural basis for recognition of hemi-methylated DNA by the SRA domain of human UHRF1

Recognition of hemi-methylated DNA by the SRA protein UHRF1 by a base-flipping mechanism

CDK inhibitors: positive and negative regulators of G1-phase progression

Cyclic nucleotide phosphodiesterase (PDE) superfamily: A new target for the development of specific therapeutic agents

Down-regulation of nuclear protein ICBP90 by p53/p21Cip1/WAF1-dependent DNA-damage checkpoint signals contributes to cell cycle arrest at G1/S transition

P304

1677-1689

http://www.w3.org/2001/XMLSchema#string

P31

scholarly article

P356

10.1002/MNFR.201100307

http://www.w3.org/2001/XMLSchema#string

P433

11

http://www.w3.org/2001/XMLSchema#string

P478

55

http://www.w3.org/2001/XMLSchema#string

P50

Christian Bronner

P577

2011-09-21T00:00:00Z

http://www.w3.org/2001/XMLSchema#dateTime

P698

22045655

http://www.w3.org/2001/XMLSchema#string

P921