New in vitro tools to study human constitutive androstane receptor (CAR) biology: discovery and comparison of human CAR inverse agonists.
about
Targeting xenobiotic receptors PXR and CAR for metabolic diseasesClinical application of transcriptional activators of bile salt transporters.CINPA1 is an inhibitor of constitutive androstane receptor that does not activate pregnane X receptor.Small-molecule modulators of the constitutive androstane receptor.Small-molecule modulators of PXR and CAR.Development of CINPA1 analogs as novel and potent inverse agonists of constitutive androstane receptorDifferences in Gene Regulation by Dual Ligands of Nuclear Receptors Constitutive Androstane Receptor (CAR) and Pregnane X Receptor (PXR) in HepG2 Cells Stably Expressing CAR/PXR.Human pregnane X receptor is activated by dibenzazepine carbamate-based inhibitors of constitutive androstane receptor.A 3D in vitro model of differentiated HepG2 cell spheroids with improved liver-like properties for repeated dose high-throughput toxicity studies.Application of Micropatterned Cocultured Hepatocytes to Evaluate the Inductive Potential and Degradation Rate of Major Xenobiotic Metabolizing Enzymes.Characterization of ligand-dependent activation of bovine and pig constitutive androstane (CAR) and pregnane X receptors (PXR) with interspecies comparisons.Nigramide J is a novel potent inverse agonist of the human constitutive androstane receptor.
P2860
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P2860
New in vitro tools to study human constitutive androstane receptor (CAR) biology: discovery and comparison of human CAR inverse agonists.
description
2011 nî lūn-bûn
@nan
2011年の論文
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2011年学术文章
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2011年学术文章
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2011年学术文章
@zh-hans
2011年学术文章
@zh-my
2011年学术文章
@zh-sg
2011年學術文章
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2011年學術文章
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2011年學術文章
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name
New in vitro tools to study hu ...... of human CAR inverse agonists.
@en
New in vitro tools to study human constitutive androstane receptor
@nl
type
label
New in vitro tools to study hu ...... of human CAR inverse agonists.
@en
New in vitro tools to study human constitutive androstane receptor
@nl
prefLabel
New in vitro tools to study hu ...... of human CAR inverse agonists.
@en
New in vitro tools to study human constitutive androstane receptor
@nl
P2093
P50
P356
P1476
New in vitro tools to study hu ...... of human CAR inverse agonists.
@en
P2093
Björn Windshügel
Johanna Jyrkkärinne
Tapio Nevalainen
Tiina Kuningas
Tuomo Laitinen
P304
P356
10.1021/MP2003658
P407
P577
2011-11-01T00:00:00Z