Role of the distal half of the c-Mpl intracellular domain in control of platelet production by thrombopoietin in vivo.
about
Cloning and characterization of a family of proteins associated with MplEndoreplication: polyploidy with purposeA structure-function analysis of serine/threonine phosphorylation of the thrombopoietin receptor, c-MplThrombopoietin induces phosphoinositol 3-kinase activation through SHP2, Gab, and insulin receptor substrate proteins in BAF3 cells and primary murine megakaryocytesAn ENU-induced recessive mutation in Mpl leads to thrombocytopenia with overdominanceMegakaryopoiesisThrombopoietin and hematopoietic stem cells.Thrombopoietin from beginning to end.Identification of the residues in the extracellular domain of thrombopoietin receptor involved in the binding of thrombopoietin and a nuclear distribution protein (human NUDC).Thrombopoietin: a tool for understanding thrombopoiesis.Signals emanating from the membrane proximal region of the thrombopoietin receptor (mpl) support hematopoietic stem cell self-renewal.The membrane-proximal region of the thrombopoietin receptor confers its high surface expression by JAK2-dependent and -independent mechanisms.Role of tumor suppressor p53 in megakaryopoiesis and platelet function.Dissection of the cytoplasmic domains of cytokine receptors involved in STAT and Ras dependent proliferation.Studies with chimeric Mpl/JAK2 receptors indicate that both JAK2 and the membrane-proximal domain of Mpl are required for cellular proliferation.The roles of phosphatidylinositol 3-kinase and protein kinase Czeta for thrombopoietin-induced mitogen-activated protein kinase activation in primary murine megakaryocytes.
P2860
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P2860
Role of the distal half of the c-Mpl intracellular domain in control of platelet production by thrombopoietin in vivo.
description
2000 nî lūn-bûn
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name
Role of the distal half of the ...... ion by thrombopoietin in vivo.
@en
Role of the distal half of the ...... ion by thrombopoietin in vivo.
@nl
type
label
Role of the distal half of the ...... ion by thrombopoietin in vivo.
@en
Role of the distal half of the ...... ion by thrombopoietin in vivo.
@nl
prefLabel
Role of the distal half of the ...... ion by thrombopoietin in vivo.
@en
Role of the distal half of the ...... ion by thrombopoietin in vivo.
@nl
P2093
P2860
P1476
Role of the distal half of the ...... ion by thrombopoietin in vivo.
@en
P2093
C W Jackson
E Stefanich
F J de Sauvage
H Steinmetz
T I Pestina
P2860
P304
P356
10.1128/MCB.20.2.507-515.2000
P407
P577
2000-01-01T00:00:00Z