Eukaryotic translation initiation factor 4GI is a cellular target for NS1 protein, a translational activator of influenza virus.
about
Mutations within the conserved NS1 nuclear export signal lead to inhibition of influenza A virus replicationPA subunit from influenza virus polymerase complex interacts with a cellular protein with homology to a family of transcriptional activatorsL13a blocks 48S assembly: role of a general initiation factor in mRNA-specific translational controlDengue virus utilizes a novel strategy for translation initiation when cap-dependent translation is inhibitedSequence of the 1918 pandemic influenza virus nonstructural gene (NS) segment and characterization of recombinant viruses bearing the 1918 NS genesA novel interaction of pokeweed antiviral protein with translation initiation factors 4G and iso4G: a potential indirect mechanism to access viral RNAs.X-ray structures of NS1 effector domain mutantsThe Influenza NS1 Protein: What Do We Know in Equine Influenza Virus Pathogenesis?Use of Aptamers as Diagnostics Tools and Antiviral Agents for Human VirusesA recombinant influenza A virus expressing an RNA-binding-defective NS1 protein induces high levels of beta interferon and is attenuated in miceInteraction of avian influenza virus NS1 protein and nucleolar and coiled-body phosphoprotein 1Influenza virus non-structural protein 1 (NS1) disrupts interferon signalingMultiple anti-interferon actions of the influenza A virus NS1 proteinPersistent host markers in pandemic and H5N1 influenza virusesFunctional genomic and serological analysis of the protective immune response resulting from vaccination of macaques with an NS1-truncated influenza virus.Mutations to PB2 and NP proteins of an avian influenza virus combine to confer efficient growth in primary human respiratory cells.The NS1 protein of the 1918 pandemic influenza virus blocks host interferon and lipid metabolism pathwaysComplete-proteome mapping of human influenza A adaptive mutations: implications for human transmissibility of zoonotic strains.Differential effects of NS1 proteins of human pandemic H1N1/2009, avian highly pathogenic H5N1, and low pathogenic H5N2 influenza A viruses on cellular pre-mRNA polyadenylation and mRNA translation.The influenza virus NS1 protein as a therapeutic target.Surveillance in Eastern India (2007-2009) revealed reassortment event involving NS and PB1-F2 gene segments among co-circulating influenza A subtypes.Mass spectrometric analysis of the N terminus of translational initiation factor eIF4G-1 reveals novel isoforms.Genetic analysis of influenza virus NS1 gene: a temperature-sensitive mutant shows defective formation of virus particles.Profiling of cellular proteins in porcine reproductive and respiratory syndrome virus virions by proteomics analysis.Efficacy of Live-Attenuated H9N2 Influenza Vaccine Candidates Containing NS1 Truncations against H9N2 Avian Influenza VirusesMutations in the NS1 protein of swine influenza virus impair anti-interferon activity and confer attenuation in pigs.Attenuation of equine influenza viruses through truncations of the NS1 proteinProtein synthesis shut-off induced by influenza virus infection is independent of PKR activityHIV-1 protease cleaves eukaryotic initiation factor 4G and inhibits cap-dependent translation.Inhibition of host translation by virus infection in vivo.Translation without eIF2 promoted by poliovirus 2A protease.Influenza A virus-induced degradation of eukaryotic translation initiation factor 4B contributes to viral replication by suppressing IFITM3 protein expression.Analysis of the Tomato spotted wilt virus ambisense S RNA-encoded hairpin structure in translation.Multifunctional adaptive NS1 mutations are selected upon human influenza virus evolution in the mouse.Generation of multiple isoforms of eukaryotic translation initiation factor 4GI by use of alternate translation initiation codons.Functional replacement of the carboxy-terminal two-thirds of the influenza A virus NS1 protein with short heterologous dimerization domains.Computational modeling of eukaryotic mRNA turnover.The NS1 protein of influenza A virus interacts with cellular processing bodies and stress granules through RNA-associated protein 55 (RAP55) during virus infectionStructure-based design of NS2 mutants for attenuated influenza A virus vaccinesDifferences in the ability to suppress interferon β production between allele A and allele B NS1 proteins from H10 influenza A viruses.
P2860
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P2860
Eukaryotic translation initiation factor 4GI is a cellular target for NS1 protein, a translational activator of influenza virus.
description
2000 nî lūn-bûn
@nan
2000年の論文
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2000年学术文章
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2000年学术文章
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2000年学术文章
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2000年学术文章
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@zh-hant
name
Eukaryotic translation initiat ...... activator of influenza virus.
@en
Eukaryotic translation initiat ...... activator of influenza virus.
@nl
type
label
Eukaryotic translation initiat ...... activator of influenza virus.
@en
Eukaryotic translation initiat ...... activator of influenza virus.
@nl
prefLabel
Eukaryotic translation initiat ...... activator of influenza virus.
@en
Eukaryotic translation initiat ...... activator of influenza virus.
@nl
P2093
P2860
P50
P1476
Eukaryotic translation initiat ...... activator of influenza virus.
@en
P2093
P2860
P304
P356
10.1128/MCB.20.17.6259-6268.2000
P407
P577
2000-09-01T00:00:00Z