about
Activation of MLK2-mediated signaling cascades by polyglutamine-expanded huntingtinNovel nuclear shuttle proteins, HDBP1 and HDBP2, bind to neuronal cell-specific cis-regulatory element in the promoter for the human Huntington's disease geneA human HAP1 homologue. Cloning, expression, and interaction with huntingtinTherapeutic potential of mood stabilizers lithium and valproic acid: beyond bipolar disorderThe predominantly HEAT-like motif structure of huntingtin and its association and coincident nuclear entry with dorsal, an NF-kB/Rel/dorsal family transcription factorReversal of a full-length mutant huntingtin neuronal cell phenotype by chemical inhibitors of polyglutamine-mediated aggregationIron dysregulation in Huntington's diseaseModulation of the glutamatergic transmission by Dopamine: a focus on Parkinson, Huntington and Addiction diseasesDeficiency of huntingtin has pleiotropic effects in the social amoeba Dictyostelium discoideumCloning of the alpha-adducin gene from the Huntington's disease candidate region of chromosome 4 by exon amplificationThe Huntington's disease candidate region exhibits many different haplotypesExpression of full-length polyglutamine-expanded Huntingtin disrupts growth factor receptor signaling in rat pheochromocytoma (PC12) cellsExpressed genes, Alu repeats and polymorphisms in cosmids sequenced from chromosome 4p16.3Benzodiazepine receptor quantification in Huntington's disease with [(123)I]omazenil and SPECTShaping the role of mitochondria in the pathogenesis of Huntington's diseaseRole of oxidative DNA damage in mitochondrial dysfunction and Huntington's disease pathogenesisMetabolism in HD: still a relevant mechanism?Cellular localization of the Huntington's disease protein and discrimination of the normal and mutated formHuntingtin is required for neurogenesis and is not impaired by the Huntington's disease CAG expansionBesides Huntington's disease, does brain-type creatine kinase play a role in other forms of hearing impairment resulting from a common pathological cause?N-terminal mutant huntingtin associates with mitochondria and impairs mitochondrial trafficking.Inactivation of Drosophila Huntingtin affects long-term adult functioning and the pathogenesis of a Huntington's disease model.Coenzyme Q protects Caenorhabditis elegans GABA neurons from calcium-dependent degeneration.Dysregulated brain creatine kinase is associated with hearing impairment in mouse models of Huntington diseaseComplex patterns of linkage disequilibrium in the Huntington disease region.Genetically modified pig models for neurodegenerative disorders.Characterization of a yeast artificial chromosome contig spanning the Huntington's disease gene candidate region.Modeling Huntington disease in yeast: perspectives and future directions.Neuroprotective effects of calmodulin peptide 76-121aa: disruption of calmodulin binding to mutant huntingtin.New mutation to Huntington's disease.Gametic but not somatic instability of CAG repeat length in Huntington's disease.A study of the Huntington's disease associated trinucleotide repeat in the Scottish population.Selective D-1 dopamine receptor agonist effects in hyperkinetic extrapyramidal disorders.Differential loss of striatal projection neurons in Huntington disease.Chromosome jumping from D4S10 (G8) toward the Huntington disease geneInstability of CAG repeats in Huntington's disease: relation to parental transmission and age of onset.Considerations in using linkage analysis as a presymptomatic test for Huntington's diseaseA yeast artificial chromosome telomere clone spanning a possible location of the Huntington disease geneHuntington's disease: pathogenesis, diagnosis and treatmentHuntington's disease: deterioration in clinical state during treatment with angiotensin converting enzyme inhibitor
P2860
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P2860
description
1986 nî lūn-bûn
@nan
1986年の論文
@ja
1986年論文
@yue
1986年論文
@zh-hant
1986年論文
@zh-hk
1986年論文
@zh-mo
1986年論文
@zh-tw
1986年论文
@wuu
1986年论文
@zh
1986年论文
@zh-cn
name
Huntington's disease. Pathogenesis and management.
@en
Huntington's disease. Pathogenesis and management.
@nl
type
label
Huntington's disease. Pathogenesis and management.
@en
Huntington's disease. Pathogenesis and management.
@nl
prefLabel
Huntington's disease. Pathogenesis and management.
@en
Huntington's disease. Pathogenesis and management.
@nl
P1476
Huntington's disease. Pathogenesis and management.
@en
P2093
P304
P356
10.1056/NEJM198611133152006
P407
P577
1986-11-01T00:00:00Z