Terminally differentiated astrocytes lack DNA damage response signaling and are radioresistant but retain DNA repair proficiency
about
Current Evidence for Developmental, Structural, and Functional Brain Defects following Prenatal Radiation ExposureConnecting Malfunctioning Glial Cells and Brain Degenerative DisordersThe Response to Oxidative DNA Damage in Neurons: Mechanisms and DiseaseRegulation of stress-inducible phosphoprotein 1 nuclear retention by protein inhibitor of activated STAT PIAS1.Targeted two-photon chemical apoptotic ablation of defined cell types in vivo.DNA damage signaling regulates age-dependent proliferative capacity of quiescent inner ear supporting cellsDNA repair kinetics in SCID mice Sertoli cells and DNA-PKcs-deficient mouse embryonic fibroblasts.Stem cells: the pursuit of genomic stability.DNA repair mechanisms in dividing and non-dividing cells.Deficiency in repair of the mitochondrial genome sensitizes proliferating myoblasts to oxidative damageBRCA1 silencing is associated with failure of DNA repairing in retinal neurocytesDifferential regulation of DNA damage response activation between somatic and germline cells in Caenorhabditis elegans.Cell cycle-dependent resolution of DNA double-strand breaks.Unique epigenetic influence of H2AX phosphorylation and H3K56 acetylation on normal stem cell radioresponses.BDNF overexpression in mouse hippocampal astrocytes promotes local neurogenesis and elicits anxiolytic-like activities.The subventricular zone is able to respond to a demyelinating lesion after localized radiation.Lessons learned about human stem cell responses to ionizing radiation exposures: a long road still ahead of us.miR-638 suppresses DNA damage repair by targeting SMC1A expression in terminally differentiated cellsA role for TRAIL/TRAIL-R2 in radiation-induced apoptosis and radiation-induced bystander response of human neural stem cellsNeural stem cells exposed to BrdU lose their global DNA methylation and undergo astrocytic differentiation.Polynucleotide kinase-phosphatase enables neurogenesis via multiple DNA repair pathways to maintain genome stability.TDP1 promotes assembly of non-homologous end joining protein complexes on DNA.Abrogation of radioresistance in glioblastoma stem-like cells by inhibition of ATM kinase.c-Fos-dependent miR-22 targets MDC1 and regulates DNA repair in terminally differentiated cells.The loss of ATP2C1 impairs the DNA damage response and induces altered skin homeostasis: Consequences for epidermal biology in Hailey-Hailey disease.DNA damage in mammalian neural stem cells leads to astrocytic differentiation mediated by BMP2 signaling through JAK-STATSurvival of neural stem cells undergoing DNA damage-induced astrocytic differentiation in self-renewal-promoting conditions in vitro.Zika virus infection dysregulates human neural stem cell growth and inhibits differentiation into neuroprogenitor cells.Contrasting effects of Krüppel-like factor 4 on X-ray-induced double-strand and single-strand DNA breaks in mouse astrocytes.Differentiation of Human Induced Pluripotent or Embryonic Stem Cells Decreases the DNA Damage Repair by Homologous Recombination.Compromized DNA repair as a basis for identification of cancer radiotherapy patients with extreme radiosensitivity.Mechanisms of Endogenous Neuroprotective Effects of Astrocytes in Brain Injury.
P2860
Q26744282-3C28C822-5E52-4F49-A8EC-6852A41B84DCQ26744443-903E9ED4-73DF-4417-B9FD-5C3A29796B9FQ26768287-4961C398-89D4-45B5-BB92-246235C6FC90Q30409858-F91A0F66-F9BA-40F9-85D6-C3D6A1F59F7BQ33883062-0BC6B944-3553-4B1C-A45C-2E7BB7D4CE40Q33910490-01C9B2C7-B0B0-4891-A6DC-F120218B9D46Q34524647-D290F1D2-840F-45FF-8A00-2076F4629225Q34685564-461629E2-100F-484E-9BBF-BC00EFFEF287Q34727858-DCC48BB2-19ED-4C26-86EB-088731A97EEFQ34997468-2C82B890-FA7F-4047-9327-8FF48D05C55FQ35185583-8EB6D1F7-83C4-4096-B346-1F49A34A2B19Q36311155-C249010C-7927-4BA9-9B57-E6C3BA40CFF4Q36782638-6EE07097-DB08-434F-AF1F-2434A4CEFFE6Q36798610-1C7DB6BF-ACBD-4FDF-8766-CC5C183E49C8Q36809785-13ADF169-B31D-441F-81AA-22C074FCE408Q36934013-4C8E27E8-55FC-4D20-A056-CCA92CDF21E0Q37139081-E8E55305-0E1D-475A-A9AC-DADB53FFCF7FQ37194235-701D4C8F-BEF0-45A1-B048-989B9AF8A209Q39070728-2CAD376D-D576-442C-A768-96A2FEA0B144Q39387716-F13A1423-D138-4550-B9CE-331EF2AF8C2EQ40625455-40F7A7C9-B693-49C9-91D8-190DD97F5B47Q41116917-8509DFCE-DD8D-4E30-AFBA-F6901DA31778Q41135787-05649779-AE1B-40BE-B8A5-88B222842399Q41471528-98206CE2-5C0F-454E-A2E9-B24FDD07130BQ41862098-350AAA0C-0409-4230-8A75-9F65C721B42EQ41871089-5D7D376A-DFE6-4AFD-BCEC-538F272A9614Q41894175-59659195-ED83-4A73-9E89-5DBBA71F7F9CQ41918070-6A677B6B-57B3-482D-B25C-6AE406BF9CD6Q46555655-299F0C48-088E-4205-A1F8-26455F503FBCQ50149415-F4B3EBF9-B22D-4248-AC9B-4F3B7DE4C709Q50562612-2F4153CF-5328-4F6F-95A6-960D0731A227Q54985162-00336A77-0246-48AC-A2B6-C923CAD862FD
P2860
Terminally differentiated astrocytes lack DNA damage response signaling and are radioresistant but retain DNA repair proficiency
description
2011 nî lūn-bûn
@nan
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
2011年论文
@zh
2011年论文
@zh-cn
name
Terminally differentiated astr ...... retain DNA repair proficiency
@en
Terminally differentiated astr ...... retain DNA repair proficiency.
@nl
type
label
Terminally differentiated astr ...... retain DNA repair proficiency
@en
Terminally differentiated astr ...... retain DNA repair proficiency.
@nl
prefLabel
Terminally differentiated astr ...... retain DNA repair proficiency
@en
Terminally differentiated astr ...... retain DNA repair proficiency.
@nl
P2860
P356
P1476
Terminally differentiated astr ...... retain DNA repair proficiency
@en
P2093
F d'Adda di Fagagna
P2860
P2888
P304
P356
10.1038/CDD.2011.129
P577
2011-10-07T00:00:00Z