Selective mitochondrial Ca2+ uptake deficit in disease endstage vulnerable motoneurons of the SOD1G93A mouse model of amyotrophic lateral sclerosis.
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Impaired Autophagy and Defective Mitochondrial Function: Converging Paths on the Road to Motor Neuron DegenerationChronic Glutamate Toxicity in Neurodegenerative Diseases-What is the Evidence?Ultrastructural studies of ALS mitochondria connect altered function and permeability with defects of mitophagy and mitochondriogenesisSOD1 misplacing and mitochondrial dysfunction in amyotrophic lateral sclerosis pathogenesisRole of mitochondria in mutant SOD1 linked amyotrophic lateral sclerosisAdenosine A2A receptors activation facilitates neuromuscular transmission in the pre-symptomatic phase of the SOD1(G93A) ALS mice, but not in the symptomatic phase.Human iPSC-derived motoneurons harbouring TARDBP or C9ORF72 ALS mutations are dysfunctional despite maintaining viabilityComparison of dendritic calcium transients in juvenile wild type and SOD1(G93A) mouse lumbar motoneurons.Elevated mRNA-levels of distinct mitochondrial and plasma membrane Ca(2+) transporters in individual hypoglossal motor neurons of endstage SOD1 transgenic mice.Seeking homeostasis: temporal trends in respiration, oxidation, and calcium in SOD1 G93A Amyotrophic Lateral Sclerosis mice.Presymptomatic and symptomatic ALS SOD1(G93A) mice differ in adenosine A1 and A2A receptor-mediated tonic modulation of neuromuscular transmission.Resveratrol improves motoneuron function and extends survival in SOD1(G93A) ALS mice.The ER mitochondria calcium cycle and ER stress response as therapeutic targets in amyotrophic lateral sclerosis.Compromised MAPK signaling in human diseases: an update.Inhibitory dysfunction in amyotrophic lateral sclerosis: future therapeutic opportunities.4-Aminopyridine Induced Activity Rescues Hypoexcitable Motor Neurons from Amyotrophic Lateral Sclerosis Patient-Derived Induced Pluripotent Stem Cells.Generation and validation of novel adeno-associated viral vectors for the analysis of Ca2+ homeostasis in motor neurons.Role of Neuroinflammation in Amyotrophic Lateral Sclerosis: Cellular Mechanisms and Therapeutic Implications.Ubiquilin1 promotes antigen-receptor mediated proliferation by eliminating mislocalized mitochondrial proteins.Dysfunctional mitochondrial Ca(2+) handling in mutant SOD1 mouse models of fALS: integration of findings from motor neuron somata and motor terminalsChronic electromyograms in treadmill running SOD1 mice reveal early changes in muscle activation.Neuroprotective Effect of Human Adipose Stem Cell-Derived Extract in Amyotrophic Lateral Sclerosis.Purinergic Receptors in Neurological Diseases With Motor Symptoms: Targets for Therapy.
P2860
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P2860
Selective mitochondrial Ca2+ uptake deficit in disease endstage vulnerable motoneurons of the SOD1G93A mouse model of amyotrophic lateral sclerosis.
description
2013 nî lūn-bûn
@nan
2013年の論文
@ja
2013年論文
@yue
2013年論文
@zh-hant
2013年論文
@zh-hk
2013年論文
@zh-mo
2013年論文
@zh-tw
2013年论文
@wuu
2013年论文
@zh
2013年论文
@zh-cn
name
Selective mitochondrial Ca2+ u ...... amyotrophic lateral sclerosis.
@en
Selective mitochondrial Ca2+ u ...... amyotrophic lateral sclerosis.
@nl
type
label
Selective mitochondrial Ca2+ u ...... amyotrophic lateral sclerosis.
@en
Selective mitochondrial Ca2+ u ...... amyotrophic lateral sclerosis.
@nl
prefLabel
Selective mitochondrial Ca2+ u ...... amyotrophic lateral sclerosis.
@en
Selective mitochondrial Ca2+ u ...... amyotrophic lateral sclerosis.
@nl
P2093
P2860
P1476
Selective mitochondrial Ca2+ u ...... amyotrophic lateral sclerosis.
@en
P2093
Andrea Fuchs
Bernhard U Keller
Burkhard Schütz
Johanna Duda
Sylvie Kutterer
Tobias Mühling
P2860
P304
P356
10.1113/JPHYSIOL.2012.247981
P407
P577
2013-02-11T00:00:00Z