Immunological unresponsiveness to native dextran B512 in young animals of dextran high responder strains is due to lack of Ig receptors expression. Evidence for a nonrandom expression of V-genes.
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DNA vaccination and the immune responsiveness of neonates.Variable region diversity in human circulating antibodies specific for the capsular polysaccharide of Haemophilus influenzae type b. Preferential usage of two types of VH3 heavy chainsEvaluation of the immunogenicity and biological activity of the Citrobacter freundii Vi-CRM197 conjugate as a vaccine for Salmonella enterica serovar TyphiPreferential expression of variable region heavy chain gene segments by predominant 2,4-dinitrophenyl-specific BALB/c neonatal antibody clonotypes.Genetic and temporal control of neonatal antibody expression.Biased expression of JH-proximal VH genes occurs in the newly generated repertoire of neonatal and adult mice.Developmentally regulated and strain-specific expression of murine VH gene families.Cellular basis for neonatally induced T-suppressor activity. Primary B cell maturation is blocked by suppressor-helper interactions restricted by loci on chromosome 12.Rise in inulin-sensitive B cells during ontogeny can be prematurely stimulated by thymus-dependent and thymus-independent antigens.Terminal deoxynucleotidyl transferase is required for an optimal response to the polysaccharide α-1,3 dextran.Stimulation of the same B-cell population by thymus-independent dextran and by thymus-dependent oligosaccharide-carrier.Immunological tolerance affects only a subpopulation of the antigen-specific B lymphocytes: evidence against clonal deletion as the mechanism of tolerance induction.A thymus-independent IgG response against dextran B512 can be induced in C57BL but not in CBA mice, even though both strains possess a VHdex gene.The immune response to the alpha 1-6 epitope of dextran is determined by a gene linked to the IgCH locus.The degree of clonal elimination in various types of specific immunological unresponsiveness.Restricted adult clonal profiles induced by neonatal immunization. Influence of suppressor T cellsMechanism of unresponsiveness to the alpha 1-6 epitope of dextran B512 in a C57BL substrain.Understanding thymus-independent antigen-induced reduction of thymus-dependent immune responses.Can B-cell signalling be understood?The immune response to bacterial dextrans. VI. No correlation between the frequency of cells expressing a major anti-dextran idiotype and the idiotype profiles of specific antibody responses.The response in old mice: positive and negative immune memory after priming in early age.The Immunoglobulin Receptors on B Cells Bind Antigen, Focus Activation Signals to Them and Initiate Antigen-Presentation
P2860
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P2860
Immunological unresponsiveness to native dextran B512 in young animals of dextran high responder strains is due to lack of Ig receptors expression. Evidence for a nonrandom expression of V-genes.
description
1978 nî lūn-bûn
@nan
1978年の論文
@ja
1978年学术文章
@wuu
1978年学术文章
@zh-cn
1978年学术文章
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1978年学术文章
@zh-my
1978年学术文章
@zh-sg
1978年學術文章
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1978年學術文章
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1978年學術文章
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name
Immunological unresponsiveness ...... nrandom expression of V-genes.
@en
Immunological unresponsiveness ...... nrandom expression of V-genes.
@nl
type
label
Immunological unresponsiveness ...... nrandom expression of V-genes.
@en
Immunological unresponsiveness ...... nrandom expression of V-genes.
@nl
prefLabel
Immunological unresponsiveness ...... nrandom expression of V-genes.
@en
Immunological unresponsiveness ...... nrandom expression of V-genes.
@nl
P2860
P356
P1476
Immunological unresponsiveness ...... nrandom expression of V-genes.
@en
P2093
P2860
P304
P356
10.1084/JEM.147.3.645
P407
P577
1978-03-01T00:00:00Z