Caspase-7 ablation modulates UPR, reprograms TRAF2-JNK apoptosis and protects T17M rhodopsin mice from severe retinal degeneration.
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Limited ATF4 Expression in Degenerating Retinas with Ongoing ER Stress Promotes Photoreceptor Survival in a Mouse Model of Autosomal Dominant Retinitis PigmentosaModulation of cellular signaling pathways in P23H rhodopsin photoreceptors.Induction of the unfolded protein response by constitutive G-protein signaling in rod photoreceptor cells.Chemical chaperone 4-phenylbutyrate prevents endoplasmic reticulum stress induced by T17M rhodopsin.Ablation of the proapoptotic genes CHOP or Ask1 does not prevent or delay loss of visual function in a P23H transgenic mouse model of retinitis pigmentosaAn activated unfolded protein response promotes retinal degeneration and triggers an inflammatory response in the mouse retina.Targeting Caspase-12 to Preserve Vision in Mice With Inherited Retinal Degeneration.Caspase-7: a critical mediator of optic nerve injury-induced retinal ganglion cell deathModulation of angiogenesis by genetic manipulation of ATF4 in mouse model of oxygen-induced retinopathy [corrected].Review: retinal degeneration: focus on the unfolded protein response.Neuroprotective Strategy in Retinal Degeneration: Suppressing ER Stress-Induced Cell Death via Inhibition of the mTOR Signal.Retinal cell death dependent reactive proliferative gliosis in the mouse retina.Amelioration of bleomycin-induced pulmonary fibrosis by chlorogenic acid through endoplasmic reticulum stress inhibition.Protective effects of placental growth factor on retinal neuronal cell damage.Non-apoptotic functions of caspase-7 during osteogenesis.The molecular and cellular basis of rhodopsin retinitis pigmentosa reveals potential strategies for therapy.Loss of the cone-enriched caspase-7 does not affect secondary cone death in retinitis pigmentosa.TNFa knockdown in the retina promotes cone survival in a mouse model of autosomal dominant retinitis pigmentosa.Translational attenuation and retinal degeneration in mice with an active integrated stress response.
P2860
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P2860
Caspase-7 ablation modulates UPR, reprograms TRAF2-JNK apoptosis and protects T17M rhodopsin mice from severe retinal degeneration.
description
2013 nî lūn-bûn
@nan
2013年の論文
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2013年学术文章
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2013年学术文章
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2013年学术文章
@zh-hans
2013年学术文章
@zh-my
2013年学术文章
@zh-sg
2013年學術文章
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2013年學術文章
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2013年學術文章
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name
Caspase-7 ablation modulates U ...... m severe retinal degeneration.
@en
Caspase-7 ablation modulates U ...... m severe retinal degeneration.
@nl
type
label
Caspase-7 ablation modulates U ...... m severe retinal degeneration.
@en
Caspase-7 ablation modulates U ...... m severe retinal degeneration.
@nl
prefLabel
Caspase-7 ablation modulates U ...... m severe retinal degeneration.
@en
Caspase-7 ablation modulates U ...... m severe retinal degeneration.
@nl
P2093
P2860
P356
P1476
Caspase-7 ablation modulates U ...... m severe retinal degeneration.
@en
P2093
M Gorbatyuk
O Gorbatyuk
S Choudhury
Y Bhootada
P2860
P356
10.1038/CDDIS.2013.34
P577
2013-03-07T00:00:00Z