Increased sensitivity to light-induced damage in a mouse model of autosomal dominant retinal disease.
about
Rhodopsin: the functional significance of asn-linked glycosylation and other post-translational modificationsMaintaining ocular safety with light exposure, focusing on devices for optogenetic stimulation.Operating in the dark: a night-vision system for surgery in retinas susceptible to light damage.Q344ter mutation causes mislocalization of rhodopsin molecules that are catalytically active: a mouse model of Q344ter-induced retinal degeneration.Acute and Protracted Cell Death in Light-Induced Retinal Degeneration in the Canine Model of Rhodopsin Autosomal Dominant Retinitis Pigmentosa.Restoration of visual function in P23H rhodopsin transgenic rats by gene delivery of BiP/Grp78Mutations of the opsin gene (Y102H and I307N) lead to light-induced degeneration of photoreceptors and constitutive activation of phototransduction in mice.Modulation of the rate of retinal degeneration in T17M RHO mice by reprogramming the unfolded protein response.Photoactivation-induced instability of rhodopsin mutants T4K and T17M in rod outer segments underlies retinal degeneration in X. laevis transgenic models of retinitis pigmentosaProbing mechanisms of photoreceptor degeneration in a new mouse model of the common form of autosomal dominant retinitis pigmentosa due to P23H opsin mutations.Chemical chaperone 4-phenylbutyrate prevents endoplasmic reticulum stress induced by T17M rhodopsin.Exclusion of the unfolded protein response in light-induced retinal degeneration in the canine T4R RHO model of autosomal dominant retinitis pigmentosa.Retinal laminar architecture in human retinitis pigmentosa caused by Rhodopsin gene mutationsThe susceptibility of the retina to photochemical damage from visible light.Autofluorescence imaging with near-infrared excitation:normalization by reflectance to reduce signal from choroidal fluorophores.Uncoupling phototoxicity-elicited neural dysmorphology and death by insidious function and selective impairment of Ran-binding protein 2 (Ranbp2).Clinical light exposure, photoreceptor degeneration, and AP-1 activation: a cell death or cell survival signal in the rhodopsin mutant retina?AAV-mediated gene therapy for retinal degeneration in the rd10 mouse containing a recessive PDEbeta mutation.A non-stop S-antigen gene mutation is associated with late onset hereditary retinal degeneration in dogs.Assessment of visual function and retinal structure following acute light exposure in the light sensitive T4R rhodopsin mutant dogComplexity of the Class B Phenotype in Autosomal Dominant Retinitis Pigmentosa Due to Rhodopsin Mutations.Steroids do not prevent photoreceptor degeneration in the light-exposed T4R rhodopsin mutant dog retina irrespective of AP-1 inhibition.Fundus Camera-Delivered Light-Induced Retinal Degeneration in Mice With the RPE65 Leu450Met Variant is Associated With Oxidative Stress and ApoptosisRetinal light damage: mechanisms and protection.Gene therapy in animal models of autosomal dominant retinitis pigmentosaCaspase-7 ablation modulates UPR, reprograms TRAF2-JNK apoptosis and protects T17M rhodopsin mice from severe retinal degeneration.Mouse models of human ocular disease for translational research.Ablation of Chop Transiently Enhances Photoreceptor Survival but Does Not Prevent Retinal Degeneration in Transgenic Mice Expressing Human P23H Rhodopsin.IRD1 and IRD2 mice, naturally occurring models of hereditary retinal dysfunction, show late-onset and progressive retinal degeneration.The molecular and cellular basis of rhodopsin retinitis pigmentosa reveals potential strategies for therapy.
P2860
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P2860
Increased sensitivity to light-induced damage in a mouse model of autosomal dominant retinal disease.
description
2007 nî lūn-bûn
@nan
2007 թուականի Մայիսին հրատարակուած գիտական յօդուած
@hyw
2007 թվականի մայիսին հրատարակված գիտական հոդված
@hy
2007年の論文
@ja
2007年論文
@yue
2007年論文
@zh-hant
2007年論文
@zh-hk
2007年論文
@zh-mo
2007年論文
@zh-tw
2007年论文
@wuu
name
Increased sensitivity to light ...... omal dominant retinal disease.
@ast
Increased sensitivity to light ...... omal dominant retinal disease.
@en
Increased sensitivity to light ...... omal dominant retinal disease.
@nl
type
label
Increased sensitivity to light ...... omal dominant retinal disease.
@ast
Increased sensitivity to light ...... omal dominant retinal disease.
@en
Increased sensitivity to light ...... omal dominant retinal disease.
@nl
prefLabel
Increased sensitivity to light ...... omal dominant retinal disease.
@ast
Increased sensitivity to light ...... omal dominant retinal disease.
@en
Increased sensitivity to light ...... omal dominant retinal disease.
@nl
P2093
P356
P1476
Increased sensitivity to light ...... omal dominant retinal disease.
@en
P2093
D Alan White
Jason J Fritz
Shalesh Kaushal
William W Hauswirth
P304
P356
10.1167/IOVS.06-1131
P407
P577
2007-05-01T00:00:00Z