FGF receptors control vitamin D and phosphate homeostasis by mediating renal FGF-23 signaling and regulating FGF-23 expression in bone.
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Idiopathic pulmonary fibrosis: current treatment options and critical appraisal of nintedanibSkeletal secretion of FGF-23 regulates phosphate and vitamin D metabolismFunctional roles of fibroblast growth factor receptors (FGFRs) signaling in human cancersProstate cancer cell-stromal cell crosstalk via FGFR1 mediates antitumor activity of dovitinib in bone metastasesWorsening endothelial function with efavirenz compared to protease inhibitors: a 12-month prospective studyOsteocyte-specific deletion of Fgfr1 suppresses FGF23Regulation of renal phosphate transport by FGF23 is mediated by FGFR1 and FGFR4Fibroblast growth factor 23 and Klotho: physiology and pathophysiology of an endocrine network of mineral metabolismFGF23 is synthesised locally by renal tubules and activates injury-primed fibroblasts.The neuroprotective effect of Klotho is mediated via regulation of members of the redox system.Renal phosphate wasting in the absence of adenylyl cyclase 6Antibody-mediated activation of FGFR1 induces FGF23 production and hypophosphatemia.Meta-analysis of genome-wide association studies identifies six new Loci for serum calcium concentrationsMembrane and integrative nuclear fibroblastic growth factor receptor (FGFR) regulation of FGF-23Role of FGF/FGFR signaling in skeletal development and homeostasis: learning from mouse models.Chronic inhibition of ERK1/2 signaling improves disordered bone and mineral metabolism in hypophosphatemic (Hyp) mice.Challenges and opportunities in the targeting of fibroblast growth factor receptors in breast cancer.Circulating αKlotho influences phosphate handling by controlling FGF23 productionInsights from genetic disorders of phosphate homeostasisWhat's new in FGF23 research?Plasma FGF23 levels increase rapidly after acute kidney injury.Calcium regulates FGF-23 expression in bone.FGF/FGFR signaling in bone formation: progress and perspectives.FGF23 and PTH--double agents at the heart of CKD.Emerging role of fibroblast growth factors 15/19 and 21 as metabolic integrators in the liver.Vitamin D in dialysis: defining deficiency and rationale for supplementation.Reducing cardiovascular mortality in chronic kidney disease: something borrowed, something new.FGF-23 and secondary hyperparathyroidism in chronic kidney disease.Approaches targeting the FGF-FGFR system: a review of the recent patent literature and associated advanced therapeutic agents.Fibroblast growth factor 19-targeted therapies for the treatment of metabolic disease.FGF23-FGF Receptor/Klotho Pathway as a New Drug Target for Disorders of Bone and Mineral Metabolism.The PTH-Vitamin D-FGF23 axis.Effects of strontium ranelate treatment on osteoblasts cultivated onto scaffolds of trabeculae bovine bone.Alterations in genes other than EGFR/ALK/ROS1 in non-small cell lung cancer: trials and treatment options.X-linked hypophosphatemia and growth.Effects of klotho deletion from bone during chronic kidney disease.Safety, pharmacokinetic, and pharmacodynamics of erdafitinib, a pan-fibroblast growth factor receptor (FGFR) tyrosine kinase inhibitor, in patients with advanced or refractory solid tumors.FGFR Inhibitor Ameliorates Hypophosphatemia and Impaired Engrailed-1/Wnt Signaling in FGF2 High Molecular Weight Isoform Transgenic Mice.A randomized, open-label study of the efficacy and safety of AZD4547 monotherapy versus paclitaxel for the treatment of advanced gastric adenocarcinoma with FGFR2 polysomy or gene amplification.Relationship of Fibroblast Growth Factor 23 (FGF-23) Serum Levels With Low Bone Mass in Postmenopausal Women.
P2860
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P2860
FGF receptors control vitamin D and phosphate homeostasis by mediating renal FGF-23 signaling and regulating FGF-23 expression in bone.
description
2011 nî lūn-bûn
@nan
2011年の論文
@ja
2011年学术文章
@wuu
2011年学术文章
@zh-cn
2011年学术文章
@zh-hans
2011年学术文章
@zh-my
2011年学术文章
@zh-sg
2011年學術文章
@yue
2011年學術文章
@zh
2011年學術文章
@zh-hant
name
FGF receptors control vitamin ...... ing FGF-23 expression in bone.
@en
FGF receptors control vitamin ...... ing FGF-23 expression in bone.
@nl
type
label
FGF receptors control vitamin ...... ing FGF-23 expression in bone.
@en
FGF receptors control vitamin ...... ing FGF-23 expression in bone.
@nl
prefLabel
FGF receptors control vitamin ...... ing FGF-23 expression in bone.
@en
FGF receptors control vitamin ...... ing FGF-23 expression in bone.
@nl
P2093
P356
P1476
FGF receptors control vitamin ...... ing FGF-23 expression in bone.
@en
P2093
Anne Thuery
Bernd Kinzel
Christelle Stamm
Diana Graus-Porta
Francesco Hofmann
Joseph Brueggen
Marcel Scheibler
Matthias Müller
Nancy E Hynes
Noemie Beluch
P304
P356
10.1002/JBMR.478
P577
2011-10-01T00:00:00Z