Development of predictive quantitative structure-activity relationship model and its application in the discovery of human leukotriene A4 hydrolase inhibitors.

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Development of predictive quantitative structure-activity relationship model and its application in the discovery of human leukotriene A4 hydrolase inhibitors.

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2013 nî lūn-bûn

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2013年の論文

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2013年学术文章

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2013年学术文章

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2013年学术文章

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2013年学术文章

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2013年学术文章

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2013年學術文章

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2013年學術文章

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2013年學術文章

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Development of predictive quan ...... riene A4 hydrolase inhibitors.

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Development of predictive quan ...... riene A4 hydrolase inhibitors.

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Development of predictive quan ...... riene A4 hydrolase inhibitors.

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Development of predictive quan ...... riene A4 hydrolase inhibitors.

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Development of predictive quan ...... riene A4 hydrolase inhibitors.

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Development of predictive quan ...... riene A4 hydrolase inhibitors.

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P1476

Development of predictive quan ...... riene A4 hydrolase inhibitors.

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P2093

Keun Woo Lee

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Minky Son

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Shalini John

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Sundarapandian Thangapandian

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Venkatesh Arulalapperumal

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P2860

Crystal structure of human leukotriene A(4) hydrolase, a bifunctional enzyme in inflammation

Structure-based dissection of the active site chemistry of leukotriene A4 hydrolase: implications for M1 aminopeptidases and inhibitor design

A second leukotriene B(4) receptor, BLT2. A new therapeutic target in inflammation and immunological disorders

Discovery of Leukotriene A4 Hydrolase Inhibitors Using Metabolomics Biased Fragment Crystallography †

Synthesis of glutamic acid analogs as potent inhibitors of leukotriene A4 hydrolase

Discovery of 4-[(2S)-2-{[4-(4-chlorophenoxy)phenoxy]methyl}-1-pyrrolidinyl]butanoic acid (DG-051) as a novel leukotriene A4 hydrolase inhibitor of leukotriene B4 biosynthesis

Experimental and computational approaches to estimate solubility and permeability in drug discovery and development settings

Structure-activity relationship studies on 1-[2-(4-Phenylphenoxy)ethyl]pyrrolidine (SC-22716), a potent inhibitor of leukotriene A(4) (LTA(4)) hydrolase

An overview of the PubChem BioAssay resource

Fast Calculation of Molecular Polar Surface Area as a Sum of Fragment-Based Contributions and Its Application to the Prediction of Drug Transport Properties

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27-40

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scholarly article

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10.4155/FMC.12.184

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P433

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P478

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2013-01-01T00:00:00Z

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23256811

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