Undetectable transcription of cap in a clinical AAV vector: implications for preformed capsid in immune responses. - Wikidata - wikimedia - TriplyDB

Undetectable transcription of cap in a clinical AAV vector: implications for preformed capsid in immune responses.

Undetectable transcription of cap in a clinical AAV vector: implications for preformed capsid in immune responses.

http://www.wikidata.org/entity/Q39501488

about

Developments in the treatment of hemophilia B: focus on emerging gene therapy Scalable downstream strategies for purification of recombinant adeno- associated virus vectors in light of the properties.Near-perfect infectivity of wild-type AAV as benchmark for infectivity of recombinant AAV vectors.Enhancing the Clinical Potential of AAV Vectors by Capsid Engineering to Evade Pre-Existing Immunity.Adeno-associated virus vectors serotype 2 induce prolonged proliferation of capsid-specific CD8+ T cells in mice.Capsid-expressing DNA in AAV vectors and its elimination by use of an oversize capsid gene for vector production.Good manufacturing practice production of self-complementary serotype 8 adeno-associated viral vector for a hemophilia B clinical trial Systemic elimination of de novo capsid protein synthesis from replication-competent AAV contamination in the liver An AAV9 coding for frataxin clearly improved the symptoms and prolonged the life of Friedreich ataxia mouse models Progress and challenges in viral vector manufacturing Advanced Characterization of DNA Molecules in rAAV Vector Preparations by Single-stranded Virus Next-generation Sequencing.Immune responses to AAV vectors: overcoming barriers to successful gene therapy Capsid antigen presentation flags human hepatocytes for destruction after transduction by adeno-associated viral vectors.The Jeremiah Metzger Lecture: gene therapy for inherited disorders: from Christmas disease to Leber's amaurosis.Transient transfection methods for clinical adeno-associated viral vector production.Elimination of contaminating cap genes in AAV vector virions reduces immune responses and improves transgene expression in a canine gene therapy model.Characteristics of Minimally Oversized Adeno-Associated Virus Vectors Encoding Human Factor VIII Generated Using Producer Cell Lines and Triple Transfection.Recent Developments in Gene Therapy for Homozygous Familial Hypercholesterolemia.DNA Minicircle Technology Improves Purity of Adeno-associated Viral Vector Preparations.Manufacturing of recombinant adeno-associated viruses using mammalian expression platforms.Liver-Directed Adeno-Associated Viral Gene Therapy for Hemophilia.Clearance and characterization of residual HSV DNA in recombinant adeno-associated virus produced by an HSV complementation system.OneBac 2.0: Sf9 Cell Lines for Production of AAV1, AAV2, and AAV8 Vectors with Minimal Encapsidation of Foreign DNA.OneBac 2.0: Sf9 Cell Lines for Production of AAV5 Vectors with Enhanced Infectivity and Minimal Encapsidation of Foreign DNA.Molecular design for recombinant adeno-associated virus (rAAV) vector production.Design and Development of AAV-based Gene Supplementation Therapies for Achromatopsia and Retinitis Pigmentosa.Product-Related Impurities in Clinical-Grade Recombinant AAV Vectors: Characterization and Risk Assessment.Pharmacology of Recombinant Adeno-associated Virus Production.

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Undetectable transcription of cap in a clinical AAV vector: implications for preformed capsid in immune responses.

http://www.wikidata.org/entity/Q39501488

description

2008 nî lūn-bûn

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2008年の論文

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2008年学术文章

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2008年学术文章

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2008年学术文章

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2008年学术文章

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2008年學術文章

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2008年學術文章

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name

Undetectable transcription of ...... ed capsid in immune responses.

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Undetectable transcription of ...... ed capsid in immune responses.

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type

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Undetectable transcription of ...... ed capsid in immune responses.

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Undetectable transcription of ...... ed capsid in immune responses.

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Undetectable transcription of ...... ed capsid in immune responses.

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Undetectable transcription of ...... ed capsid in immune responses.

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Molecular Therapy

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Undetectable transcription of ...... ed capsid in immune responses.

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Bernd Hauck

http://www.w3.org/2001/XMLSchema#string

Federico Mingozzi

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Guang Qu

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J Fraser Wright

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Jürg M Sommer

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Katherine A High

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Olga Zelenaia

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Peter H Smith

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Samuel L Murphy

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Xingge Liu

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P2860

Evidence for packaging of rep-cap sequences into adeno-associated virus (AAV) type 2 capsids in the absence of inverted terminal repeats: a model for generation of rep-positive AAV particles.

Safety and efficacy of gene transfer for Leber's congenital amaurosis

Successful transduction of liver in hemophilia by AAV-Factor IX and limitations imposed by the host immune response

Identification of mouse AAV capsid-specific CD8+ T cell epitopes.

Characterization of wild-type adeno-associated virus type 2-like particles generated during recombinant viral vector production and strategies for their elimination

DNA helicase-mediated packaging of adeno-associated virus type 2 genomes into preformed capsids

Adeno-associated virus vectors in clinical trials.

Adeno-associated virus vectors can be efficiently produced without helper virus.

Use of adeno-associated virus as a general transduction vector for mammalian cells.

Adeno-associated virus type 2 DNA replication in vivo: mutation analyses of the D sequence in viral inverted terminal repeats.

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144-152

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10.1038/MT.2008.227

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1

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18941440

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