Halohydrin dehalogenases are structurally and mechanistically related to short-chain dehydrogenases/reductases
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Medium- and short-chain dehydrogenase/reductase gene and protein families : the SDR superfamily: functional and structural diversity within a family of metabolic and regulatory enzymesStructure and mechanism of a bacterial haloalcohol dehalogenase: a new variation of the short-chain dehydrogenase/reductase fold without an NAD(P)H binding siteBiocatalytic and structural properties of a highly engineered halohydrin dehalogenaseCrystal structures of halohydrin hydrogen-halide-lyases from Corynebacterium sp. N-1074Structures of Proline Utilization A Reveal the Fold and Functions of the Aldehyde Dehydrogenase Superfamily Domain of Unknown FunctionRecent advances on halohydrin dehalogenases-from enzyme identification to novel biocatalytic applicationsNovel dehalogenase mechanism for 2,3-dichloro-1-propanol utilization in Pseudomonas putida strain MC4.Expanding the Halohydrin Dehalogenase Enzyme Family: Identification of Novel Enzymes by Database Mining.A high-throughput adrenaline test for the exploration of the catalytic potential of halohydrin dehalogenases in epoxide ring-opening reactions.Exploring the enantioselective mechanism of halohydrin dehalogenase from Agrobacterium radiobacter AD1 by iterative saturation mutagenesisExpanding the enzyme universe: accessing non-natural reactions by mechanism-guided directed evolution.An efficient high-throughput screening assay for rapid directed evolution of halohydrin dehalogenase for preparation of β-substituted alcohols.Key residues for controlling enantioselectivity of Halohydrin dehalogenase from Arthrobacter sp. strain AD2, revealed by structure-guided directed evolution.A robust cosolvent-compatible halohydrin dehalogenase by computational library design.Exploring the thermostable properties of halohydrin dehalogenase from Agrobacterium radiobacter AD1 by a combinatorial directed evolution strategy.Enhancing the biocatalytic manufacture of the key intermediate of atorvastatin by focused directed evolution of halohydrin dehalogenaseProperties and biotechnological applications of halohydrin dehalogenases: current state and future perspectives.Chemical and enzymatic approaches to the synthesis of optically pure ethyl (R)-4-cyano-3-hydroxybutanoate.Enzymatic Halogenation and Dehalogenation Reactions: Pervasive and Mechanistically Diverse.Dehalogenation Activity of Selected Fungi Toward δ-Iodo-γ-Lactone Derived from trans,trans-Farnesol.Exacerbation of substrate toxicity by IPTG in Escherichia coli BL21(DE3) carrying a synthetic metabolic pathway.Combinatorial metabolic engineering of Pseudomonas putida KT2440 for efficient mineralization of 1,2,3-trichloropropane.The X-ray structure of the haloalcohol dehalogenase HheA from Arthrobacter sp. strain AD2: insight into enantioselectivity and halide binding in the haloalcohol dehalogenase family.Effect of Zn2+ on halohydrin dehalogenase expression and accumulation through multi-parameter correlation research with Escherichia coli P84A/MC1061.Maximizing the efficiency of multienzyme process by stoichiometry optimization.Purification, gene cloning, and characterization of a novel halohydrin dehalogenase from Agromyces mediolanus ZJB120203.Expression, characterization, and improvement of a newly cloned halohydrin dehalogenase from Agrobacterium tumefaciens and its application in production of epichlorohydrin.Nitrite-mediated synthesis of chiral epichlorohydrin using halohydrin dehalogenase from Agrobacterium radiobacter AD1.
P2860
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P2860
Halohydrin dehalogenases are structurally and mechanistically related to short-chain dehydrogenases/reductases
description
2001 nî lūn-bûn
@nan
2001年の論文
@ja
2001年学术文章
@wuu
2001年学术文章
@zh-cn
2001年学术文章
@zh-hans
2001年学术文章
@zh-my
2001年学术文章
@zh-sg
2001年學術文章
@yue
2001年學術文章
@zh
2001年學術文章
@zh-hant
name
Halohydrin dehalogenases are s ...... hain dehydrogenases/reductases
@en
Halohydrin dehalogenases are s ...... ain dehydrogenases/reductases.
@nl
type
label
Halohydrin dehalogenases are s ...... hain dehydrogenases/reductases
@en
Halohydrin dehalogenases are s ...... ain dehydrogenases/reductases.
@nl
prefLabel
Halohydrin dehalogenases are s ...... hain dehydrogenases/reductases
@en
Halohydrin dehalogenases are s ...... ain dehydrogenases/reductases.
@nl
P2093
P2860
P1476
Halohydrin dehalogenases are s ...... hain dehydrogenases/reductases
@en
P2093
Fraaije MW
Janssen DB
Lutje Spelberg JH
Poelarends GJ
van Hylckama Vlieg JE
van Merode AE
P2860
P304
P356
10.1128/JB.183.17.5058-5066.2001
P407
P577
2001-09-01T00:00:00Z