CHEK2 genomic and proteomic analyses reveal genetic inactivation or endogenous activation across the 60 cell lines of the US National Cancer Institute.
about
Trial Watch: Targeting ATM-CHK2 and ATR-CHK1 pathways for anticancer therapyX-ray structures of checkpoint kinase 2 in complex with inhibitors that target its gatekeeper-dependent hydrophobic pocketStructural characterization of inhibitor complexes with checkpoint kinase 2 (Chk2), a drug target for cancer therapyTargeting of Chk2 as a countermeasure to dose-limiting toxicity triggered by topoisomerase-II (TOP2) poisonsFunctional categories associated with clusters of genes that are co-expressed across the NCI-60 cancer cell linesConcordance of gene expression and functional correlation patterns across the NCI-60 cell lines and the Cancer Genome Atlas glioblastoma samples.CHEK2 (∗) 1100delC Mutation and Risk of Prostate Cancer.CellMiner: a web-based suite of genomic and pharmacologic tools to explore transcript and drug patterns in the NCI-60 cell line set.CHEK2 mutation and risk of prostate cancer: a systematic review and meta-analysis.Phenotypic and Molecular Characterization of MCF10DCIS and SUM Breast Cancer Cell Lines.The exomes of the NCI-60 panel: a genomic resource for cancer biology and systems pharmacology.Versatile in vivo regulation of tumor phenotypes by dCas9-mediated transcriptional perturbation.Transcription poisoning by Topoisomerase I is controlled by gene length, splice sites, and miR-142-3p
P2860
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P2860
CHEK2 genomic and proteomic analyses reveal genetic inactivation or endogenous activation across the 60 cell lines of the US National Cancer Institute.
description
2011 nî lūn-bûn
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2011年の論文
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2011年学术文章
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2011年学术文章
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2011年学术文章
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2011年学术文章
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2011年学术文章
@zh-sg
2011年學術文章
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2011年學術文章
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name
CHEK2 genomic and proteomic an ...... US National Cancer Institute.
@en
CHEK2 genomic and proteomic an ...... US National Cancer Institute.
@nl
type
label
CHEK2 genomic and proteomic an ...... US National Cancer Institute.
@en
CHEK2 genomic and proteomic an ...... US National Cancer Institute.
@nl
prefLabel
CHEK2 genomic and proteomic an ...... US National Cancer Institute.
@en
CHEK2 genomic and proteomic an ...... US National Cancer Institute.
@nl
P2093
P2860
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CHEK2 genomic and proteomic an ...... e US National Cancer Institute
@en
P2093
J H Doroshow
J W Connelly
P S Meltzer
R H Shoemaker
P2860
P2888
P304
P356
10.1038/ONC.2011.283
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P577
2011-07-18T00:00:00Z