Mediator MED23 links insulin signaling to the adipogenesis transcription cascade.
about
S6K1 plays a critical role in early adipocyte differentiationThe Mediator complex: a central integrator of transcriptionInsulin inhibits lipolysis in adipocytes via the evolutionarily conserved mTORC1-Egr1-ATGL-mediated pathwayA cardiac microRNA governs systemic energy homeostasis by regulation of MED13Ankrd26 gene disruption enhances adipogenesis of mouse embryonic fibroblastsT-cells null for the MED23 subunit of mediator express decreased levels of KLF2 and inefficiently populate the peripheral lymphoid organsMED14 tethers mediator to the N-terminal domain of peroxisome proliferator-activated receptor gamma and is required for full transcriptional activity and adipogenesis.Mediator and human diseaseThe Hippo effector Yorkie activates transcription by interacting with a histone methyltransferase complex through Ncoa6.Liver Med23 ablation improves glucose and lipid metabolism through modulating FOXO1 activity.Mediator complex dependent regulation of cardiac development and disease.MED13-dependent signaling from the heart confers leanness by enhancing metabolism in adipose tissue and liverRecruitment of Mediator Complex by Cell Type and Stage-Specific Factors Required for Tissue-Specific TAF Dependent Gene Activation in an Adult Stem Cell Lineage.Drosophila TRF2 and TAF9 regulate lipid droplet size and phospholipid fatty acid compositionMediator MED23 plays opposing roles in directing smooth muscle cell and adipocyte differentiation.Selective requirement for Mediator MED23 in Ras-active lung cancer.The Mediator subunit MED23 couples H2B mono-ubiquitination to transcriptional control and cell fate determination.Dual functions of TAF7L in adipocyte differentiation.Genome-wide association study of L-arginine and dimethylarginines reveals novel metabolic pathway for symmetric dimethylarginine.Mediator MED23 cooperates with RUNX2 to drive osteoblast differentiation and bone development.The Mediator Complex and Lipid Metabolism.Regulation of metabolism by the Mediator complex.PPARs: diverse regulators in energy metabolism and metabolic diseases.The metazoan Mediator co-activator complex as an integrative hub for transcriptional regulation.Genomic and biochemical insights into the specificity of ETS transcription factors.Role of protein tyrosine phosphatases in the modulation of insulin signaling and their implication in the pathogenesis of obesity-linked insulin resistance.'Mediator-ing' messenger RNA processing.Cyclin C regulates adipogenesis by stimulating transcriptional activity of CCAAT/enhancer-binding protein α.Mediator subunit 23 overexpression as a novel target for suppressing proliferation and tumorigenesis in hepatocellular carcinoma.Downregulation of MED23 promoted the tumorigenecity of esophageal squamous cell carcinoma.Mediator MED23 regulates basal transcription in vivo via an interaction with P-TEFb.The E3 ubiquitin ligase TRIM23 regulates adipocyte differentiation via stabilization of the adipogenic activator PPARγ.ERK phosphorylation of MED14 in promoter complexes during mitogen-induced gene activation by Elk-1THRAP3 interacts with HELZ2 and plays a novel role in adipocyte differentiation.Opposing effects of Elk-1 multisite phosphorylation shape its response to ERK activationMediator phosphorylation prevents stress response transcription during non-stress conditionsMediator complex regulates alternative mRNA processing via the MED23 subunit.Discovery of Novel Splice Variants and Regulatory Mechanisms for Microsomal Triglyceride Transfer Protein in Human Tissues.The mediator subunit Med23 contributes to controlling T-cell activation and prevents autoimmunity.Control of Muscle Metabolism by the Mediator Complex.
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P2860
Mediator MED23 links insulin signaling to the adipogenesis transcription cascade.
description
2009 nî lūn-bûn
@nan
2009年の論文
@ja
2009年論文
@yue
2009年論文
@zh-hant
2009年論文
@zh-hk
2009年論文
@zh-mo
2009年論文
@zh-tw
2009年论文
@wuu
2009年论文
@zh
2009年论文
@zh-cn
name
Mediator MED23 links insulin signaling to the adipogenesis transcription cascade.
@en
Mediator MED23 links insulin signaling to the adipogenesis transcription cascade.
@nl
type
label
Mediator MED23 links insulin signaling to the adipogenesis transcription cascade.
@en
Mediator MED23 links insulin signaling to the adipogenesis transcription cascade.
@nl
prefLabel
Mediator MED23 links insulin signaling to the adipogenesis transcription cascade.
@en
Mediator MED23 links insulin signaling to the adipogenesis transcription cascade.
@nl
P2093
P2860
P1433
P1476
Mediator MED23 links insulin signaling to the adipogenesis transcription cascade.
@en
P2093
Arnold J Berk
Jeffrey M Friedman
Jing-wen Yin
P2860
P304
P356
10.1016/J.DEVCEL.2009.04.006
P407
P577
2009-05-01T00:00:00Z