The RNA-methyltransferase Misu (NSun2) poises epidermal stem cells to differentiate.
about
Widespread occurrence of 5-methylcytosine in human coding and non-coding RNANSun2-mediated cytosine-5 methylation of vault noncoding RNA determines its processing into regulatory small RNAsmRNA methylation by NSUN2 in cell proliferationLandmarks in the Evolution of (t)-RNAs from the Origin of Life up to Their Present Role in Human CognitionGenome recoding by tRNA modificationsVital roles of stem cells and biomaterials in skin tissue engineeringModify or die?--RNA modification defects in metazoansDefects in tRNA Anticodon Loop 2'-O-Methylation Are Implicated in Nonsyndromic X-Linked Intellectual Disability due to Mutations in FTSJ1The mouse cytosine-5 RNA methyltransferase NSun2 is a component of the chromatoid body and required for testis differentiationNovel skin phenotypes revealed by a genome-wide mouse reverse genetic screen.Resting no more: re-defining telogen, the maintenance stage of the hair growth cycleSox4 links tumor suppression to accelerated aging in mice by modulating stem cell activationIdentification of genes important for cutaneous function revealed by a large scale reverse genetic screen in the mouseTranscriptome-Wide Mapping of RNA 5-Methylcytosine in Arabidopsis mRNAs and Noncoding RNAs.Overexpression of NSUN2 by DNA hypomethylation is associated with metastatic progression in human breast cancer.Characterizing 5-methylcytosine in the mammalian epitranscriptome.Understanding RNA modifications: the promises and technological bottlenecks of the 'epitranscriptome'.tRNA modifying enzymes, NSUN2 and METTL1, determine sensitivity to 5-fluorouracil in HeLa cellsWhole exome sequencing identifies a splicing mutation in NSUN2 as a cause of a Dubowitz-like syndromeMethylation by NSun2 represses the levels and function of microRNA 125b.Aberrant methylation of tRNAs links cellular stress to neuro-developmental disorders.Identification of direct targets and modified bases of RNA cytosine methyltransferases.Role of RNA methyltransferases in tissue renewal and pathologyNovel RNA modifications in the nervous system: form and functionConservation of tRNA and rRNA 5-methylcytosine in the kingdom Plantae.Mutation in NSUN2, which encodes an RNA methyltransferase, causes autosomal-recessive intellectual disability.Mutations in NSUN2 cause autosomal-recessive intellectual disability.The tRNA methyltransferase Dnmt2 is required for accurate polypeptide synthesis during haematopoiesis.NSun2 Promotes Cell Growth via Elevating Cyclin-Dependent Kinase 1 Translation.Proteinase-activated receptor 2 promotes cancer cell migration through RNA methylation-mediated repression of miR-125b.Symmetric Epistasis Estimation (SEE) and its application to dissecting interaction map of Plasmodium falciparumTargeting the unique methylation pattern of androgen receptor (AR) promoter in prostate stem/progenitor cells with 5-aza-2'-deoxycytidine (5-AZA) leads to suppressed prostate tumorigenesis.tRNA-derived microRNA modulates proliferation and the DNA damage response and is down-regulated in B cell lymphoma.Posttranscriptional methylation of transfer and ribosomal RNA in stress response pathways, cell differentiation, and cancerStem cell function and stress response are controlled by protein synthesis.Deciphering the epitranscriptome: A green perspective.Cytosine-5 RNA Methylation Regulates Neural Stem Cell Differentiation and MotilityLarge-scale mouse knockouts and phenotypes.Mapping and significance of the mRNA methylome.miRNA and methylation: a multifaceted liaison.
P2860
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P2860
The RNA-methyltransferase Misu (NSun2) poises epidermal stem cells to differentiate.
description
2011 nî lūn-bûn
@nan
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
2011年论文
@zh
2011年论文
@zh-cn
name
The RNA-methyltransferase Misu (NSun2) poises epidermal stem cells to differentiate.
@en
The RNA-methyltransferase Misu
@nl
type
label
The RNA-methyltransferase Misu (NSun2) poises epidermal stem cells to differentiate.
@en
The RNA-methyltransferase Misu
@nl
prefLabel
The RNA-methyltransferase Misu (NSun2) poises epidermal stem cells to differentiate.
@en
The RNA-methyltransferase Misu
@nl
P2860
P50
P1433
P1476
The RNA-methyltransferase Misu (NSun2) poises epidermal stem cells to differentiate.
@en
P2860
P304
P356
10.1371/JOURNAL.PGEN.1002403
P577
2011-12-01T00:00:00Z