KIBRA suppresses apical exocytosis through inhibition of aPKC kinase activity in epithelial cells.
about
Evolutionary and molecular facts link the WWC protein family to Hippo signalingThe Regulatory Role of KIBRA and PTPN14 in Hippo Signaling and BeyondEmerging role of cell polarity proteins in breast cancer progression and metastasisSignaling pathways in cell polarity.Common exonic missense variants in the C2 domain of the human KIBRA protein modify lipid binding and cognitive performance.KIBRA: In the brain and beyondMyosin 5b loss of function leads to defects in polarized signaling: implication for microvillus inclusion disease pathogenesis and treatment.Nuf and Rip11 requirement for polarity determinant recycling during Drosophila development.PAR3 and aPKC regulate Golgi organization through CLASP2 phosphorylation to generate cell polarity.Candidate genes in quantitative trait loci associated with absolute and relative kidney weight in rats with Inherited Stress Induced Arterial Hypertension.Hippo signaling pathway in liver and pancreas: the potential drug target for tumor therapy.Zonula occludens-1 and -2 regulate apical cell structure and the zonula adherens cytoskeleton in polarized epithelia.Nuclear fallout provides a new link between aPKC and polarized cell trafficking.KIBRA regulates aurora kinase activity and is required for precise chromosome alignment during mitosis.p120-catenin controls contractility along the vertical axis of epithelial lateral membranesCreation of trophectoderm, the first epithelium, in mouse preimplantation development.KIBRA promotes prostate cancer cell proliferation and motility.aPKC Inhibition by Par3 CR3 Flanking Regions Controls Substrate Access and Underpins Apical-Junctional Polarization.Phosphorylation of KIBRA by the extracellular signal-regulated kinase (ERK)-ribosomal S6 kinase (RSK) cascade modulates cell proliferation and migration.The Angiomotins--from discovery to function.Rewiring cell polarity signaling in cancer.Tissue-specific differences in the regulation of KIBRA gene expression involve transcription factor TCF7L2 and a complex alternative promoter system.Phospho-regulation of KIBRA by CDK1 and CDC14 phosphatase controls cell-cycle progression.The KIBRA-aPKC connection: A potential regulator of membrane trafficking and cell polarity.aPKCλ maintains the integrity of the glomerular slit diaphragm through trafficking of nephrin to the cell surface.Elevated expression of Par3 promotes prostate cancer metastasis by forming a Par3/aPKC/KIBRA complex and inactivating the hippo pathwayaPKC phosphorylates p27Xic1, providing a mechanistic link between apicobasal polarity and cell-cycle control.Deletion of KIBRA, protein expressed in kidney and brain, increases filopodial-like long dendritic spines in neocortical and hippocampal neurons in vivo and in vitro.High expression of KIBRA in low atypical protein kinase C-expressing gastric cancer correlates with lymphatic invasion and poor prognosis.KIBRA attains oncogenic activity by repressing RASSF1A.Distinctive phosphoinositide and Ca2+ binding properties of normal and cognitive performance-linked variant forms of KIBRA C2 domain.Signaling-Dependent Control of Apical Membrane Size and Self-Renewal in Rosette-Stage Human Neuroepithelial Stem Cells.
P2860
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P2860
KIBRA suppresses apical exocytosis through inhibition of aPKC kinase activity in epithelial cells.
description
2011 nî lūn-bûn
@nan
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
2011年论文
@zh
2011年论文
@zh-cn
name
KIBRA suppresses apical exocyt ...... activity in epithelial cells.
@en
KIBRA suppresses apical exocyt ...... activity in epithelial cells.
@nl
type
label
KIBRA suppresses apical exocyt ...... activity in epithelial cells.
@en
KIBRA suppresses apical exocyt ...... activity in epithelial cells.
@nl
prefLabel
KIBRA suppresses apical exocyt ...... activity in epithelial cells.
@en
KIBRA suppresses apical exocyt ...... activity in epithelial cells.
@nl
P2093
P50
P1433
P1476
KIBRA suppresses apical exocyt ...... e activity in epithelial cells
@en
P2093
Atsushi Suzuki
Kazuhiro Chida
Kazunori Sasaki
Takashi Ohtsuka
Yohei Yoshihama
P304
P356
10.1016/J.CUB.2011.03.029
P407
P577
2011-04-14T00:00:00Z