Distinct roles for histone methyltransferases G9a and GLP in cancer germ-line antigen gene regulation in human cancer cells and murine embryonic stem cells.
about
A chemical probe selectively inhibits G9a and GLP methyltransferase activity in cellsNucleosomes containing methylated DNA stabilize DNA methyltransferases 3A/3B and ensure faithful epigenetic inheritanceRegulation of cancer germline antigen gene expression: implications for cancer immunotherapy.BORIS/CTCFL expression is insufficient for cancer-germline antigen gene expression and DNA hypomethylation in ovarian cell lines.Investigation of genes important in neurodevelopment disorders in adult human brain.Epigenetic hierarchy within the MAGEA1 cancer-germline gene: promoter DNA methylation dictates local histone modifications.Coordinated cancer germline antigen promoter and global DNA hypomethylation in ovarian cancer: association with the BORIS/CTCF expression ratio and advanced stageInhibition of histone lysine methylation enhances cancer-testis antigen expression in lung cancer cells: implications for adoptive immunotherapy of cancerSelective inhibitors of protein methyltransferasesOptimization of cellular activity of G9a inhibitors 7-aminoalkoxy-quinazolinesConstitutional tandem duplication of 9q34 that truncates EHMT1 in a child with ganglioglioma.Lysine methyltransferase G9a is not required for DNMT3A/3B anchoring to methylated nucleosomes and maintenance of DNA methylation in somatic cellsIs Friedreich ataxia an epigenetic disorder?Immunomodulatory action of the DNA methyltransferase inhibitor SGI-110 in epithelial ovarian cancer cells and xenografts.DNA methylation of the Fthl17 5'-upstream region regulates differential Fthl17 expression in lung cancer cells and germline stem cells.Genetic determinants of FOXM1 overexpression in epithelial ovarian cancer and functional contribution to cell cycle progression.EHMT2 directs DNA methylation for efficient gene silencing in mouse embryos.Large, male germ cell-specific hypomethylated DNA domains with unique genomic and epigenomic features on the mouse X chromosome.Discovery of an in vivo chemical probe of the lysine methyltransferases G9a and GLP.DNA methylation and nucleosome occupancy regulate the cancer germline antigen gene MAGEA11.PRAME expression and promoter hypomethylation in epithelial ovarian cancer.The biology of cancer testis antigens: putative function, regulation and therapeutic potentialInhibitors of Protein Methyltransferases and Demethylases.Lack of evidence for green tea polyphenols as DNA methylation inhibitors in murine prostate.Euchromatic histone lysine methyltransferase 1 regulates cancer development in human gastric cancer by regulating E-cadherin.
P2860
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P2860
Distinct roles for histone methyltransferases G9a and GLP in cancer germ-line antigen gene regulation in human cancer cells and murine embryonic stem cells.
description
2009 nî lūn-bûn
@nan
2009年の論文
@ja
2009年論文
@yue
2009年論文
@zh-hant
2009年論文
@zh-hk
2009年論文
@zh-mo
2009年論文
@zh-tw
2009年论文
@wuu
2009年论文
@zh
2009年论文
@zh-cn
name
Distinct roles for histone met ...... d murine embryonic stem cells.
@en
Distinct roles for histone met ...... d murine embryonic stem cells.
@nl
type
label
Distinct roles for histone met ...... d murine embryonic stem cells.
@en
Distinct roles for histone met ...... d murine embryonic stem cells.
@nl
prefLabel
Distinct roles for histone met ...... d murine embryonic stem cells.
@en
Distinct roles for histone met ...... d murine embryonic stem cells.
@nl
P2093
P2860
P1476
Distinct roles for histone met ...... d murine embryonic stem cells.
@en
P2093
Adam R Karpf
Anna Woloszynska-Read
Makoto Tachibana
Omkaram Gangisetty
Petra A Link
Smitha R James
Yoichi Shinkai
P2860
P304
P356
10.1158/1541-7786.MCR-08-0497
P577
2009-06-16T00:00:00Z