The pleckstrin homology and phosphotyrosine binding domains of insulin receptor substrate 1 mediate inhibition of apoptosis by insulin
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Placental overgrowth in mice lacking the imprinted gene IplIRS-4 mediates protein kinase B signaling during insulin stimulation without promoting antiapoptosisMechanisms of regulation of cell adhesion and motility by insulin receptor substrate-1 in prostate cancer cellsETV6-NTRK3 transformation requires insulin-like growth factor 1 receptor signaling and is associated with constitutive IRS-1 tyrosine phosphorylationDifferential roles of CIDEA and CIDEC in insulin-induced anti-apoptosis and lipid droplet formation in human adipocytes.IGF-I receptor signalling in transformation and differentiation.Regulation of Id gene expression by type I insulin-like growth factor: roles of Stat3 and the tyrosine 950 residue of the receptor.Ankyrin repeat and SOCS box containing protein 4 (Asb-4) colocalizes with insulin receptor substrate 4 (IRS4) in the hypothalamic neurons and mediates IRS4 degradationTranscriptional regulation by insulin: from the receptor to the gene.Contribution of insulin resistance to vascular dysfunction.Insulin signaling meets mitochondria in metabolism.Multiple roles for the p85α isoform in the regulation and function of PI3K signalling and receptor trafficking.Differential activation of protein kinase B and p70(S6)K by glucose and insulin-like growth factor 1 in pancreatic beta-cells (INS-1).TNF down-regulation of receptor tyrosine kinase-dependent mitogenic signal pathways as an important step in cytostasis induction and commitment to apoptosis of Kym-1 rhabdomyosarcoma cells.Cellular compartmentalization in insulin action: altered signaling by a lipid-modified IRS-1.Insulin receptor substrate-2 mediated insulin-like growth factor-I receptor overexpression in pancreatic adenocarcinoma through protein kinase Cdelta.The role of insulin receptor substrate-1 in transformation by v-src.Transformation by the simian virus 40 T antigen is regulated by IGF-I receptor and IRS-1 signaling.Nutrient-dependent and insulin-stimulated phosphorylation of insulin receptor substrate-1 on serine 302 correlates with increased insulin signaling.Role of insulin receptor substrates and protein kinase C-zeta in vascular permeability factor/vascular endothelial growth factor expression in pancreatic cancer cells.Differential roles of insulin receptor substrates in the anti-apoptotic function of insulin-like growth factor-1 and insulin.Nuclear translocation of insulin receptor substrate-1 by the simian virus 40 T antigen and the activated type 1 insulin-like growth factor receptor.The role of the insulin receptor substrate-1 in the differentiation of rat hippocampal neuronal cells.Regulation of Id2 gene expression by the insulin-like growth factor I receptor requires signaling by phosphatidylinositol 3-kinase.Insulin receptor substrate-1, p70S6K, and cell size in transformation and differentiation of hemopoietic cells.Stimulation of pancreatic beta-cell proliferation by growth hormone is glucose-dependent: signal transduction via janus kinase 2 (JAK2)/signal transducer and activator of transcription 5 (STAT5) with no crosstalk to insulin receptor substrate-mediatThe carboxyl terminal extension of the Drosophila insulin receptor homologue binds IRS-1 and influences cell survival.Insulin receptor substrate (IRS)-1 regulates murine embryonic stem (mES) cells self-renewal.A novel transcript is up-regulated by fasting in the hypothalamus and enhances insulin signalling.Insulin antiapoptotic signaling involves insulin activation of the nuclear factor kappaB-dependent survival genes encoding tumor necrosis factor receptor-associated factor 2 and manganese-superoxide dismutase.Role of the PI3-kinase/mTor pathway in the regulation of the stearoyl CoA desaturase (SCD1) gene expression by insulin in liver.Activation of serum- and glucocorticoid-induced protein kinase (Sgk) by cyclic AMP and insulin.Nuclear translocation of insulin receptor substrate-1 by oncogenes and Igf-I. Effect on ribosomal RNA synthesis.Insulin impairs the maturation of chondrocytes in vitro.Insulin reduces apoptosis and increases DNA synthesis and cell size via distinct signalling pathways in Drosophila Kc cells.Role of insulin receptor substrate-2 in interleukin-9-dependent proliferation
P2860
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P2860
The pleckstrin homology and phosphotyrosine binding domains of insulin receptor substrate 1 mediate inhibition of apoptosis by insulin
description
1998 nî lūn-bûn
@nan
1998年の論文
@ja
1998年論文
@yue
1998年論文
@zh-hant
1998年論文
@zh-hk
1998年論文
@zh-mo
1998年論文
@zh-tw
1998年论文
@wuu
1998年论文
@zh
1998年论文
@zh-cn
name
The pleckstrin homology and ph ...... bition of apoptosis by insulin
@en
The pleckstrin homology and ph ...... ition of apoptosis by insulin.
@nl
type
label
The pleckstrin homology and ph ...... bition of apoptosis by insulin
@en
The pleckstrin homology and ph ...... ition of apoptosis by insulin.
@nl
prefLabel
The pleckstrin homology and ph ...... bition of apoptosis by insulin
@en
The pleckstrin homology and ph ...... ition of apoptosis by insulin.
@nl
P2093
P2860
P356
P1476
The pleckstrin homology and ph ...... bition of apoptosis by insulin
@en
P2093
P2860
P304
P356
10.1128/MCB.18.11.6784
P407
P577
1998-11-01T00:00:00Z