PP2A inhibitors induce apoptosis in pancreatic cancer cell line PANC-1 through persistent phosphorylation of IKKα and sustained activation of the NF-κB pathway.
about
LB100, a small molecule inhibitor of PP2A with potent chemo- and radio-sensitizing potentialPP2A: The Wolf in Sheep's Clothing?PP2A inhibitors suppress migration and growth of PANC-1 pancreatic cancer cells through inhibition on the Wnt/β-catenin pathway by phosphorylation and degradation of β-catenin.Development of a gene therapy strategy to target hepatocellular carcinoma based inhibition of protein phosphatase 2A using the α-fetoprotein promoter enhancer and pgk promoter: an in vitro and in vivo studyThe natural compound cantharidin induces cancer cell death through inhibition of heat shock protein 70 (HSP70) and Bcl-2-associated athanogene domain 3 (BAG3) expression by blocking heat shock factor 1 (HSF1) binding to promoters.Cantharidins induce ER stress and a terminal unfolded protein response in OSCC.Tamoxifen enhances the anticancer effect of cantharidin and norcantharidin in pancreatic cancer cell lines through inhibition of the protein kinase C signaling pathway.MiR-196a promotes pancreatic cancer progression by targeting nuclear factor kappa-B-inhibitor alphaCantharidin represses invasion of pancreatic cancer cells through accelerated degradation of MMP2 mRNA.Overexpression of protein phosphatase 4 correlates with poor prognosis in patients with stage II pancreatic ductal adenocarcinoma.Cell survival and metastasis regulation by Akt signaling in colorectal cancerInflammatory stimuli promote growth and invasion of pancreatic cancer cells through NF-κB pathway dependent repression of PP2Ac.Cantharidin and norcantharidin inhibit the ability of MCF-7 cells to adhere to platelets via protein kinase C pathway-dependent downregulation of α2 integrin.Cantharidin Overcomes Imatinib Resistance by Depleting BCR-ABL in Chronic Myeloid Leukemia.TNF-α sensitizes chemotherapy and radiotherapy against breast cancer cells.Terpenoids: natural products for cancer therapy.The regulatory roles of phosphatases in cancer.PP2A-Mediated Anticancer Therapy.Cantharidin alters the expression of genes associated with the NKG2D-associated immune response in TSGH-8301 human bladder carcinoma cells.Anticancer effects of cantharidin in A431 human skin cancer (Epidermoid carcinoma) cells in vitro and in vivo.Cantharidin Induces Apoptosis Through the Calcium/PKC-Regulated Endoplasmic Reticulum Stress Pathway in Human Bladder Cancer Cells.Augmented Anticancer Effects of Cantharidin with Liposomal Encapsulation: In Vitro and In Vivo Evaluation.
P2860
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P2860
PP2A inhibitors induce apoptosis in pancreatic cancer cell line PANC-1 through persistent phosphorylation of IKKα and sustained activation of the NF-κB pathway.
description
2011 nî lūn-bûn
@nan
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
2011年论文
@zh
2011年论文
@zh-cn
name
PP2A inhibitors induce apoptos ...... tivation of the NF-κB pathway.
@en
PP2A inhibitors induce apoptos ...... tivation of the NF-κB pathway.
@nl
type
label
PP2A inhibitors induce apoptos ...... tivation of the NF-κB pathway.
@en
PP2A inhibitors induce apoptos ...... tivation of the NF-κB pathway.
@nl
prefLabel
PP2A inhibitors induce apoptos ...... tivation of the NF-κB pathway.
@en
PP2A inhibitors induce apoptos ...... tivation of the NF-κB pathway.
@nl
P2093
P1433
P1476
PP2A inhibitors induce apoptos ...... tivation of the NF-κB pathway.
@en
P2093
Feiran Gong
Jinghuan Lv
Jingjing Zhang
P304
P356
10.1016/J.CANLET.2011.02.009
P407
P577
2011-03-03T00:00:00Z