Dependence of adenovirus infectivity on length of the fiber shaft domain.
about
Activation of P2X(7) receptor by ATP plays an important role in regulating inflammatory responses during acute viral infectionAdenovirus serotype 30 fiber does not mediate transduction via the coxsackie-adenovirus receptor.Current developments in adenovirus-based cancer gene therapyDevelopment of adenovirus capsid proteins for targeted therapeutic deliveryAdenovirus Binding to Blood Factors Results in Liver Cell Infection and HepatotoxicityIdentification of CD46 Binding Sites within the Adenovirus Serotype 35 Fiber KnobExploring the atomic structure and conformational flexibility of a 320 Å long engineered viral fiber using X-ray crystallographyCell entry and trafficking of human adenovirus bound to blood factor X is determined by the fiber serotype and not hexon:heparan sulfate interactionImproved gene delivery to intestinal mucosa by adenoviral vectors bearing subgroup B and d fibers.Protein crystals in Adenovirus type 5-infected cells: requirements for intranuclear crystallogenesis, structural and functional analysisRedundant and synergistic mechanisms control the sequestration of blood-born adenovirus in the liver.Chimeric adenoviral vectors incorporating a fiber of human adenovirus 3 efficiently mediate gene transfer into prostate cancer cells.Structural analysis of a fiber-pseudotyped adenovirus with ocular tropism suggests differential modes of cell receptor interactions.The distal short consensus repeats 1 and 2 of the membrane cofactor protein CD46 and their distance from the cell membrane determine productive entry of species B adenovirus serotype 35Adenovirus receptors.Adenovirus receptors and their implications in gene deliveryCrystal structure of human adenovirus at 3.5 A resolutionReduction of natural adenovirus tropism to mouse liver by fiber-shaft exchange in combination with both CAR- and alphav integrin-binding ablation.Molecular characterization of a lizard adenovirus reveals the first atadenovirus with two fiber genes and the first adenovirus with either one short or three long fibers per pentonEvaluation of biodistribution and safety of adenovirus vectors containing group B fibers after intravenous injection into baboons.Artificial extension of the adenovirus fiber shaft inhibits infectivity in coxsackievirus and adenovirus receptor-positive cell lines.Modulation of adenovirus vector tropism via incorporation of polypeptide ligands into the fiber protein.Subgroup B and F fiber chimeras eliminate normal adenovirus type 5 vector transduction in vitro and in vivo.Reduction of natural adenovirus tropism to the liver by both ablation of fiber-coxsackievirus and adenovirus receptor interaction and use of replaceable short fiber.Current progress in the development of a prophylactic vaccine for HIV-1.Mutation of the fiber shaft heparan sulphate binding site of a 5/3 chimeric adenovirus reduces liver tropism.Characterization of species C human adenovirus serotype 6 (Ad6)AdenovirusPolymer-enhanced delivery increases adenoviral gene expression in an orthotopic model of bladder cancerGeneration of a Kupffer cell-evading adenovirus for systemic and liver-directed gene transfer.IL-1α and complement cooperate in triggering local neutrophilic inflammation in response to adenovirus and eliminating virus-containing cellsHeterogeneity of the fibre sequence in subgenus C adenoviruses.Differential immunogenicity between HAdV-5 and chimpanzee adenovirus vector ChAdOx1 is independent of fiber and penton RGD loop sequences in miceFiber shaft-chimeric adenovirus vectors lacking the KKTK motif efficiently infect liver cells in vivoConserved fiber-penton base interaction revealed by nearly atomic resolution cryo-electron microscopy of the structure of adenovirus provides insight into receptor interaction.T-cell immunotherapy for adenoviral infections of stem-cell transplant recipients.Reduced infectivity of adenovirus type 5 particles and degradation of entering viral genomes associated with incomplete processing of the preterminal protein.Current advances and future challenges in Adenoviral vector biology and targetingAdenovirus serotype 5 hexon is critical for virus infection of hepatocytes in vivo.Characterization of an Oncolytic Adenovirus Vector Constructed to Target the cMet Receptor
P2860
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P2860
Dependence of adenovirus infectivity on length of the fiber shaft domain.
description
2000 nî lūn-bûn
@nan
2000年の論文
@ja
2000年論文
@yue
2000年論文
@zh-hant
2000年論文
@zh-hk
2000年論文
@zh-mo
2000年論文
@zh-tw
2000年论文
@wuu
2000年论文
@zh
2000年论文
@zh-cn
name
Dependence of adenovirus infectivity on length of the fiber shaft domain.
@en
Dependence of adenovirus infectivity on length of the fiber shaft domain.
@nl
type
label
Dependence of adenovirus infectivity on length of the fiber shaft domain.
@en
Dependence of adenovirus infectivity on length of the fiber shaft domain.
@nl
prefLabel
Dependence of adenovirus infectivity on length of the fiber shaft domain.
@en
Dependence of adenovirus infectivity on length of the fiber shaft domain.
@nl
P2860
P1433
P1476
Dependence of adenovirus infectivity on length of the fiber shaft domain.
@en
P2093
Shayakhmetov DM
P2860
P304
10274-10286
P356
10.1128/JVI.74.22.10274-10286.2000
P407
P577
2000-11-01T00:00:00Z