Metabolic activation and covalent binding to nucleic acids of carcinogenic heterocyclic amines from cooked foods and amino acid pyrolysates.

Metabolic activation and covalent binding to nucleic acids of carcinogenic heterocyclic amines from cooked foods and amino acid pyrolysates.

Item
http://www.wikidata.org/entity/Q39595113
Human cytochrome P-450PA (P-450IA2), the phenacetin O-deethylase, is primarily responsible for the hepatic 3-demethylation of caffeine and N-oxidation of carcinogenic arylaminesMetabolism and biomarkers of heterocyclic aromatic amines in molecular epidemiology studies: lessons learned from aromatic aminesCaffeine Cytochrome P450 1A2 Metabolic Phenotype Does Not Predict the Metabolism of Heterocyclic Aromatic Amines in Humans.Cytochrome P450-mediated metabolism and DNA binding of 2-amino-1,7-dimethylimidazo[4,5-g]quinoxaline and its carcinogenic isomer 2-amino-3,8-dimethylimidazo[4,5-f]quinoxaline in mice.Interaction of the cytochrome P4501A2, SULT1A1 and NAT gene polymorphisms with smoking and dietary mutagen intake in modification of the risk of pancreatic cancerCarcinogen metabolism genes, red meat and poultry intake, and colorectal cancer risk.Evidence of direct generation of oxygen free radicals from heterocyclic amines by NADPH/cytochrome P-450 reductase in vitro.Strong inhibition of 2-amino-6-methyldipyrido[1,2-a:3',2'-d] imidazole-induced mutagenesis and hepatocarcinogenesis by 1-O-hexyl-2,3,5-trimethylhydroquinone.Metabolic activation of pyrolysate arylamines by human liver microsomes; possible involvement of a P-488-H type cytochrome P-450.DNA adducts formed by 2-amino-3,8-dimethylimidazo[4,5-f]quinoxaline in rat liver: dose-response on chronic administration.Induction of DNA recombination by activated 3-amino-1-methyl-5H-pyrido[4,3-b]indole.Activation of 2-hydroxyamino-1-methyl-6-phenylimidazo[4,5-b] pyridine by cDNA-expressed human and rat arylsulfotransferases.
P2860

Metabolic activation and covalent binding to nucleic acids of carcinogenic heterocyclic amines from cooked foods and amino acid pyrolysates.

Item
http://www.wikidata.org/entity/Q39595113
description
1987 nî lūn-bûn
@nan
1987年の論文
@ja
1987年論文
@yue
1987年論文
@zh-hant
1987年論文
@zh-hk
1987年論文
@zh-mo
1987年論文
@zh-tw
1987年论文
@wuu
1987年论文
@zh
1987年论文
@zh-cn
name
Metabolic activation and coval ...... ds and amino acid pyrolysates.
@en
Metabolic activation and coval ...... ds and amino acid pyrolysates.
@nl
type
label
Metabolic activation and coval ...... ds and amino acid pyrolysates.
@en
Metabolic activation and coval ...... ds and amino acid pyrolysates.
@nl
prefLabel
Metabolic activation and coval ...... ds and amino acid pyrolysates.
@en
Metabolic activation and coval ...... ds and amino acid pyrolysates.
@nl
P1433
P1476
P2093
P304
P31
P433
P478
P577
P698
P1433
P1476
Metabolic activation and coval ...... ds and amino acid pyrolysates.
@en
P2093
P304
P31
P433
P478
P577
P698