Degradation of the retinoblastoma tumor suppressor by the human papillomavirus type 16 E7 oncoprotein is important for functional inactivation and is separable from proteasomal degradation of E7.
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Regulated degradation of the HIV-1 Vpu protein through a betaTrCP-independent pathway limits the release of viral particlesAssociation of the human papillomavirus type 16 E7 oncoprotein with the 600-kDa retinoblastoma protein-associated factor, p600The global transcriptional effects of the human papillomavirus E6 protein in cervical carcinoma cell lines are mediated by the E6AP ubiquitin ligase.Epstein-Barr virus latent antigen 3C can mediate the degradation of the retinoblastoma protein through an SCF cellular ubiquitin ligaseHuman papillomavirus oncoprotein E6 inactivates the transcriptional coactivator human ADA3The E7 oncoprotein is translated from spliced E6*I transcripts in high-risk human papillomavirus type 16- or type 18-positive cervical cancer cell lines via translation reinitiationBrd4-independent transcriptional repression function of the papillomavirus e2 proteinsThe association of mammalian DREAM complex and HPV16 E7 proteinsMicroRNAs Expressed during Viral Infection: Biomarker Potential and Therapeutic ConsiderationsDown-regulation of the retinoblastoma tumor suppressor by the hepatitis C virus NS5B RNA-dependent RNA polymeraseSubstrate selection by the proteasome during degradation of protein complexesTargeting proteins for degradationInteraction between the HPV E7 oncoprotein and the transcriptional coactivator p300Role of the ubiquitin system and tumor viruses in AIDS-related cancer.Abrogation of the Brd4-positive transcription elongation factor B complex by papillomavirus E2 protein contributes to viral oncogene repressionHPV infection and EGFR activation/alteration in HIV-infected East African patients with conjunctival carcinomaThe human papillomavirus type 58 E7 oncoprotein modulates cell cycle regulatory proteins and abrogates cell cycle checkpoints.Papillomavirus interaction with cellular chromatin.Human papilloma virus E7 oncoprotein abrogates the p53-p21-DREAM pathway.Retinoblastoma-independent antiproliferative activity of novel intracellular antibodies against the E7 oncoprotein in HPV 16-positive cellsCritical roles for non-pRb targets of human papillomavirus type 16 E7 in cervical carcinogenesisLow- and high-risk human papillomavirus E7 proteins regulate p130 differentlyPotent anti-tumor effect generated by a novel human papillomavirus (HPV) antagonist peptide reactivating the pRb/E2F pathway.Examination of the pRb-dependent and pRb-independent functions of E7 in vivo.Human papillomavirus E7 requires the protease calpain to degrade the retinoblastoma protein.Systematic identification of interactions between host cell proteins and E7 oncoproteins from diverse human papillomaviruses.The human papilloma virus E7 oncoprotein inhibits transforming growth factor-beta signaling by blocking binding of the Smad complex to its target sequence.Interactions with pocket proteins contribute to the role of human papillomavirus type 16 E7 in the papillomavirus life cycle.Signals that dictate nuclear localization of human papillomavirus type 16 oncoprotein E6 in living cellsThe E7 proteins of low- and high-risk human papillomaviruses share the ability to target the pRB family member p130 for degradationThree regions of the pRB pocket domain affect its inactivation by human papillomavirus E7 proteins.Inactivation of both the retinoblastoma tumor suppressor and p21 by the human papillomavirus type 16 E7 oncoprotein is necessary to inhibit cell cycle arrest in human epithelial cells.A humanized mouse model of HPV-associated pathology driven by E7 expressionViral oncogenes, noncoding RNAs, and RNA splicing in human tumor virusesSRp20 is a proto-oncogene critical for cell proliferation and tumor induction and maintenance.Biological activities and molecular targets of the human papillomavirus E7 oncoprotein.Epstein-Barr virus nuclear antigen 3C regulated genes in lymphoblastoid cell lines.Molecular Strategies of Deoxynucleotide Triphosphate Supply Inhibition Used in the Treatment of Gynecologic MalignanciesExpression of human papillomavirus type 16 E7 is sufficient to significantly increase expression of angiogenic factors but is not sufficient to induce endothelial cell migration.p66(Shc) restrains Ras hyperactivation and suppresses metastatic behavior.
P2860
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P2860
Degradation of the retinoblastoma tumor suppressor by the human papillomavirus type 16 E7 oncoprotein is important for functional inactivation and is separable from proteasomal degradation of E7.
description
2001 nî lūn-bûn
@nan
2001年の論文
@ja
2001年論文
@yue
2001年論文
@zh-hant
2001年論文
@zh-hk
2001年論文
@zh-mo
2001年論文
@zh-tw
2001年论文
@wuu
2001年论文
@zh
2001年论文
@zh-cn
name
Degradation of the retinoblast ...... proteasomal degradation of E7.
@en
Degradation of the retinoblast ...... proteasomal degradation of E7.
@nl
type
label
Degradation of the retinoblast ...... proteasomal degradation of E7.
@en
Degradation of the retinoblast ...... proteasomal degradation of E7.
@nl
prefLabel
Degradation of the retinoblast ...... proteasomal degradation of E7.
@en
Degradation of the retinoblast ...... proteasomal degradation of E7.
@nl
P2093
P2860
P1433
P1476
Degradation of the retinoblast ...... proteasomal degradation of E7.
@en
P2093
P2860
P304
P356
10.1128/JVI.75.16.7583-7591.2001
P407
P577
2001-08-01T00:00:00Z