A systematic analysis of human papillomavirus (HPV) E6 PDZ substrates identifies MAGI-1 as a major target of HPV type 16 (HPV-16) and HPV-18 whose loss accompanies disruption of tight junctions.
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Viral Interactions with PDZ Domain-Containing Proteins-An Oncogenic Trait?Human Papillomaviruses; Epithelial Tropisms, and the Development of NeoplasiaA viral-human interactome based on structural motif-domain interactions captures the human infectomePapillomavirus E6 oncoproteins.The role of MALAT1 correlates with HPV in cervical cancer.Roles of the PDZ-binding motif of HPV 16 E6 protein in oncogenic transformation of human cervical keratinocytes.Regulation of interferon-β by MAGI-1 and its interaction with influenza A virus NS1 protein with ESEV PBMPDZRN3/LNX3 is a novel target of human papillomavirus type 16 (HPV-16) and HPV-18 E6.HPV-16 impairs the subcellular distribution and levels of expression of protein phosphatase 1γ in cervical malignancyEmerging theme: cellular PDZ proteins as common targets of pathogenic viruses.The Human Papillomavirus E6 PDZ Binding Motif: From Life Cycle to Malignancy.Quantifying domain-ligand affinities and specificities by high-throughput holdup assay.Magi Is Associated with the Par Complex and Functions Antagonistically with Bazooka to Regulate the Apical Polarity ComplexA Drosophila Model of HPV E6-Induced Malignancy Reveals Essential Roles for Magi and the Insulin ReceptorInteraction of the Human Papillomavirus E6 Oncoprotein with Sorting Nexin 27 Modulates Endocytic Cargo Transport PathwaysZinc reduces epithelial barrier compromise induced by human seminal plasma.Nip the HPV encoded evil in the cancer bud: HPV reshapes TRAILs and signaling landscapesProduction of functional, stable, unmutated recombinant human papillomavirus E6 oncoprotein: implications for HPV-tumor diagnosis and therapy.Human papillomavirus molecular biology and disease association.PDZ domains: the building blocks regulating tumorigenesis.Human papillomaviruses and the specificity of PDZ domain targeting.Human papillomavirus (HPV)-18 E6 oncoprotein interferes with the epithelial cell polarity Par3 protein.Human T-cell leukemia virus type 1 Tax protein interacts with and mislocalizes the PDZ domain protein MAGI-1.A functional network of the tumor suppressors APC, hDlg, and PTEN, that relies on recognition of specific PDZ-domains.Peptide-Protein Binding Investigated by Far-IR Spectroscopy and Molecular Dynamics Simulations.Restoration of MAGI-1 expression in human papillomavirus-positive tumor cells induces cell growth arrest and apoptosis.A genome-wide functional screen shows MAGI-1 is an L1CAM-dependent stabilizer of apical junctions in C. elegans.Roles of the PDZ domain-binding motif of the human papillomavirus type 16 E6 on the immortalization and differentiation of primary human foreskin keratinocytes.Human tumour viruses and the deregulation of cell polarity in cancer.Molecular cloning, alternative splicing and mRNA expression analysis of MAGI1 and its correlation with laying performance in geese.Particular gene upregulation and p53 heterogeneous expression in TP53-mutated maxillary carcinoma.Comparative analysis of micro-RNAs in human papillomavirus-positive versus -negative oropharyngeal cancers.Human Papillomavirus E6 interaction with cellular PDZ domain proteins modulates YAP nuclear localization.
P2860
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P2860
A systematic analysis of human papillomavirus (HPV) E6 PDZ substrates identifies MAGI-1 as a major target of HPV type 16 (HPV-16) and HPV-18 whose loss accompanies disruption of tight junctions.
description
2010 nî lūn-bûn
@nan
2010年の論文
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2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
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name
A systematic analysis of human ...... disruption of tight junctions.
@en
A systematic analysis of human papillomavirus
@nl
type
label
A systematic analysis of human ...... disruption of tight junctions.
@en
A systematic analysis of human papillomavirus
@nl
prefLabel
A systematic analysis of human ...... disruption of tight junctions.
@en
A systematic analysis of human papillomavirus
@nl
P2860
P356
P1433
P1476
A systematic analysis of human ...... disruption of tight junctions.
@en
P2093
Christian Kranjec
Lawrence Banks
P2860
P304
P356
10.1128/JVI.01756-10
P407
P577
2010-12-01T00:00:00Z