Possible mechanisms of emphysema in smokers. In vitro suppression of serum elastase-inhibitory capacity by fresh cigarette smoke and its prevention by antioxidants.
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Chronic CSE treatment induces the growth of normal oral keratinocytes via PDK2 upregulation, increased glycolysis and HIF1α stabilizationIdentification and analysis of the promoter region of the human methionine sulphoxide reductase A geneTobacco smoke induces the generation of procoagulant microvesicles from human monocytes/macrophagesalpha1-Antitrypsin deficiency . 6: new and emerging treatments for alpha1-antitrypsin deficiencyCollaborative interactions between neutrophil elastase and metalloproteinases in extracellular matrix degradation in three-dimensional collagen gelsGlutathione peroxidase inhibitory assay for electrophilic pollutants in diesel exhaust and tobacco smokeSIRT1 is a redox-sensitive deacetylase that is post-translationally modified by oxidants and carbonyl stressLycopene inhibits NF-kB-mediated IL-8 expression and changes redox and PPARγ signalling in cigarette smoke-stimulated macrophagesIL-17RA is required for CCL2 expression, macrophage recruitment, and emphysema in response to cigarette smoke.Paracrine potential of fibroblasts exposed to cigarette smoke extract with vascular growth factor inductionRole of connective tissue proteases in the pathogenesis of chronic inflammatory lung diseaseNicotine stimulates nerve growth factor in lung fibroblasts through an NFκB-dependent mechanism.Altered cigarette smoke-induced lung inflammation due to ablation of Grx1Biological effects of cigarette smoke in cultured human retinal pigment epithelial cells.Raised serum concentrations of pancreatic enzymes in cigarette smokers.Cigarette smoke can activate the alternative pathway of complement in vitro by modifying the third component of complementCigarette smoke attenuates the RIG-I-initiated innate antiviral response to influenza infection in two murine models.Aryl hydrocarbon receptor-dependent retention of nuclear HuR suppresses cigarette smoke-induced cyclooxygenase-2 expression independent of DNA-binding.Free-radical chemistry of cigarette smoke and its toxicological implications.Cigarette smoke extract suppresses the RIG-I-initiated innate immune response to influenza virus in the human lung.Cigarette smoke causes caspase-independent apoptosis of bronchial epithelial cells from asthmatic donors.Pathogenesis of the adult respiratory distress syndrome. Evidence of oxidant activity in bronchoalveolar lavage fluid.Cigarette smoke extract induces a phenotypic shift in epithelial cells; involvement of HIF1α in mesenchymal transition.Oxidants spontaneously released by alveolar macrophages of cigarette smokers can inactivate the active site of alpha 1-antitrypsin, rendering it ineffective as an inhibitor of neutrophil elastaseZ-type alpha 1-antitrypsin is less competent than M1-type alpha 1-antitrypsin as an inhibitor of neutrophil elastase.Plasma levels of elastase-specific fibrinopeptides correlate with proteinase inhibitor phenotype. Evidence for increased elastase activity in subjects with homozygous and heterozygous deficiency of alpha 1-proteinase inhibitorGenetic ablation of the aryl hydrocarbon receptor causes cigarette smoke-induced mitochondrial dysfunction and apoptosisCardiac development in zebrafish and human embryonic stem cells is inhibited by exposure to tobacco cigarettes and e-cigarettesPlasminogen activator inhibitor-1 in cigarette smoke exposure and influenza A virus infection-induced lung injury.Cigarette smoke targets glutaredoxin 1, increasing s-glutathionylation and epithelial cell death.Mitogen- and stress-activated kinase 1 (MSK1) regulates cigarette smoke-induced histone modifications on NF-κB-dependent genesProstacyclin prevents pulmonary endothelial cell apoptosis induced by cigarette smoke.Developmental effects of tobacco smoke exposure during human embryonic stem cell differentiation are mediated through the transforming growth factor-β superfamily member, Nodal.Impaired nuclear factor erythroid 2-related factor 2 expression increases apoptosis of airway epithelial cells in patients with chronic obstructive pulmonary disease due to cigarette smoking.Inflammatory and immune processes in the human lung in health and disease: evaluation by bronchoalveolar lavage.Lung injury induced by leukocytic proteases.Inhibitory capacity of alpha 1 antitrypsin in lung secretions: variability and the effect of drugs.Klotho expression is reduced in COPD airway epithelial cells: effects on inflammation and oxidant injuryRAGE and tobacco smoke: insights into modeling chronic obstructive pulmonary disease.Potential mechanism of emphysema: alpha 1-proteinase inhibitor recovered from lungs of cigarette smokers contains oxidized methionine and has decreased elastase inhibitory capacity.
P2860
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P2860
Possible mechanisms of emphysema in smokers. In vitro suppression of serum elastase-inhibitory capacity by fresh cigarette smoke and its prevention by antioxidants.
description
1978 nî lūn-bûn
@nan
1978年の論文
@ja
1978年論文
@yue
1978年論文
@zh-hant
1978年論文
@zh-hk
1978年論文
@zh-mo
1978年論文
@zh-tw
1978年论文
@wuu
1978年论文
@zh
1978年论文
@zh-cn
name
Possible mechanisms of emphyse ...... ts prevention by antioxidants.
@en
Possible mechanisms of emphyse ...... ts prevention by antioxidants.
@nl
type
label
Possible mechanisms of emphyse ...... ts prevention by antioxidants.
@en
Possible mechanisms of emphyse ...... ts prevention by antioxidants.
@nl
prefLabel
Possible mechanisms of emphyse ...... ts prevention by antioxidants.
@en
Possible mechanisms of emphyse ...... ts prevention by antioxidants.
@nl
P1476
Possible mechanisms of emphyse ...... ts prevention by antioxidants.
@en
P304
P356
10.1164/ARRD.1978.118.3.617
P577
1978-09-01T00:00:00Z