Efficient and specific knockdown of small non-coding RNAs in mammalian cells and in mice.
about
linc-HOXA1 is a noncoding RNA that represses Hoxa1 transcription in cisHuman RNase H1 is associated with protein P32 and is involved in mitochondrial pre-rRNA processingTargeting of repeated sequences unique to a gene results in significant increases in antisense oligonucleotide potency.Cellular localization of long non-coding RNAs affects silencing by RNAi more than by antisense oligonucleotides.Non-polyadenylated transcription in embryonic stem cells reveals novel non-coding RNA related to pluripotency and differentiationBiology and applications of small nucleolar RNAs.RNA cleavage products generated by antisense oligonucleotides and siRNAs are processed by the RNA surveillance machinery.Identification and characterization of intracellular proteins that bind oligonucleotides with phosphorothioate linkages.TCP1 complex proteins interact with phosphorothioate oligonucleotides and can co-localize in oligonucleotide-induced nuclear bodies in mammalian cells.The rates of the major steps in the molecular mechanism of RNase H1-dependent antisense oligonucleotide induced degradation of RNA.A snoRNA modulates mRNA 3' end processing and regulates the expression of a subset of mRNAs.The Y3** ncRNA promotes the 3' end processing of histone mRNAs.siRNAs targeted to certain polyadenylation sites promote specific, RISC-independent degradation of messenger RNAs.Translation efficiency of mRNAs is increased by antisense oligonucleotides targeting upstream open reading frames.Antisense oligonucleotides targeting translation inhibitory elements in 5' UTRs can selectively increase protein levels.snoRNAs associate with mRNA 3' processing complex: New wine in old bottles.Translation can affect the antisense activity of RNase H1-dependent oligonucleotides targeting mRNAs.Dynamic nucleoplasmic and nucleolar localization of mammalian RNase H1 in response to RNAP I transcriptional R-loops.RNase H1-Dependent Antisense Oligonucleotides Are Robustly Active in Directing RNA Cleavage in Both the Cytoplasm and the Nucleus.Neuronal differentiation induces SNORD115 expression and is accompanied by post-transcriptional changes of serotonin receptor 2c mRNA.COPII vesicles can affect the activity of antisense oligonucleotides by facilitating the release of oligonucleotides from endocytic pathways
P2860
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P2860
Efficient and specific knockdown of small non-coding RNAs in mammalian cells and in mice.
description
2010 nî lūn-bûn
@nan
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
2010年论文
@zh
2010年论文
@zh-cn
name
Efficient and specific knockdown of small non-coding RNAs in mammalian cells and in mice.
@en
Efficient and specific knockdown of small non-coding RNAs in mammalian cells and in mice.
@nl
type
label
Efficient and specific knockdown of small non-coding RNAs in mammalian cells and in mice.
@en
Efficient and specific knockdown of small non-coding RNAs in mammalian cells and in mice.
@nl
prefLabel
Efficient and specific knockdown of small non-coding RNAs in mammalian cells and in mice.
@en
Efficient and specific knockdown of small non-coding RNAs in mammalian cells and in mice.
@nl
P2093
P2860
P356
P1476
Efficient and specific knockdown of small non-coding RNAs in mammalian cells and in mice.
@en
P2093
Shuling Guo
Stanley T Crooke
Timothy A Vickers
Xue-hai Liang
P2860
P356
10.1093/NAR/GKQ1121
P407
P577
2010-11-09T00:00:00Z