Regulation of protein phosphatase 2A methylation by LCMT1 and PME-1 plays a critical role in differentiation of neuroblastoma cells
about
Protein phosphatase 2A dysfunction in Alzheimer's diseaseThe pharmacological landscape and therapeutic potential of serine hydrolasesCircumventing embryonic lethality with Lcmt1 deficiency: generation of hypomorphic Lcmt1 mice with reduced protein phosphatase 2A methyltransferase expression and defects in insulin signalingSilencing PP2A inhibitor by lenti-shRNA interference ameliorates neuropathologies and memory deficits in tg2576 mice.Academic cross-fertilization by public screening yields a remarkable class of protein phosphatase methylesterase-1 inhibitors.FAT1 cadherin acts upstream of Hippo signalling through TAZ to regulate neuronal differentiation.Discovery and optimization of sulfonyl acrylonitriles as selective, covalent inhibitors of protein phosphatase methylesterase-1.The metabolic serine hydrolases and their functions in mammalian physiology and disease.PP2A inhibition determines poor outcome and doxorubicin resistance in early breast cancer and its activation shows promising therapeutic effectsThe protein phosphatase PP2A/Bα binds to the microtubule-associated proteins Tau and MAP2 at a motif also recognized by the kinase Fyn: implications for tauopathies.Leucine carboxyl methyltransferase 1 (LCMT1)-dependent methylation regulates the association of protein phosphatase 2A and Tau protein with plasma membrane microdomains in neuroblastoma cellsDysregulation of protein phosphatase 2A in parkinson disease and dementia with lewy bodies.FAM122A, a new endogenous inhibitor of protein phosphatase 2AFurther understanding of tau phosphorylation: implications for therapy.All roads lead to PP2A: exploiting the therapeutic potential of this phosphatase.Deregulation of the protein phosphatase 2A, PP2A in cancer: complexity and therapeutic options.NNMT Silencing Activates Tumor Suppressor PP2A, Inactivates Oncogenic STKs, and Inhibits Tumor Forming Ability.Protein phosphatase 2A is involved in the tyrosine hydroxylase phosphorylation regulated by α-synuclein.Multivalent cross-linking of actin filaments and microtubules through the microtubule-associated protein Tau.Lysophosphatidylcholine Drives Neuroblast Cell Fate.
P2860
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P2860
Regulation of protein phosphatase 2A methylation by LCMT1 and PME-1 plays a critical role in differentiation of neuroblastoma cells
description
2010 nî lūn-bûn
@nan
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
2010年论文
@zh
2010年论文
@zh-cn
name
Regulation of protein phosphat ...... tiation of neuroblastoma cells
@en
Regulation of protein phosphat ...... iation of neuroblastoma cells.
@nl
type
label
Regulation of protein phosphat ...... tiation of neuroblastoma cells
@en
Regulation of protein phosphat ...... iation of neuroblastoma cells.
@nl
prefLabel
Regulation of protein phosphat ...... tiation of neuroblastoma cells
@en
Regulation of protein phosphat ...... iation of neuroblastoma cells.
@nl
P2093
P2860
P1476
Regulation of protein phosphat ...... tiation of neuroblastoma cells
@en
P2093
Estelle Sontag
Jean-Marie Sontag
Martina Mitterhuber
Viyada Nunbhakdi-Craig
P2860
P304
P356
10.1111/J.1471-4159.2010.07049.X
P407
P50
P577
2010-11-04T00:00:00Z