Influenza A virus protein PB1-F2 exacerbates IFN-beta expression of human respiratory epithelial cells.
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Influenza A virus PB1-F2 protein expression is regulated in a strain-specific manner by sequences located downstream of the PB1-F2 initiation codon.Molecular determinants of influenza virus pathogenesis in mice.Effect of 1918 PB1-F2 expression on influenza A virus infection kinetics.Pandemic (H1N1) 2009 influenza virus induces weaker host immune responses in vitro: a possible mechanism of high transmissibility.Restored PB1-F2 in the 2009 pandemic H1N1 influenza virus has minimal effects in swine.Molecular basis of the structure and function of H1 hemagglutinin of influenza virus.Kinetics of coinfection with influenza A virus and Streptococcus pneumoniae.NLRX1 prevents mitochondrial induced apoptosis and enhances macrophage antiviral immunity by interacting with influenza virus PB1-F2 protein.PB1-F2 attenuates virulence of highly pathogenic avian H5N1 influenza virus in chickens.The influenza virus protein PB1-F2 inhibits the induction of type I interferon at the level of the MAVS adaptor protein.Transcriptomic analysis of host immune and cell death responses associated with the influenza A virus PB1-F2 protein.Role of position 627 of PB2 and the multibasic cleavage site of the hemagglutinin in the virulence of H5N1 avian influenza virus in chickens and ducks.A single N66S mutation in the PB1-F2 protein of influenza A virus increases virulence by inhibiting the early interferon response in vivoChicken cyclophilin A is an inhibitory factor to influenza virus replication.Kinetic characterization of PB1-F2-mediated immunopathology during highly pathogenic avian H5N1 influenza virus infectionAnalysis of antiviral response in human epithelial cells infected with hepatitis E virus.The influenza virus protein PB1-F2 interacts with IKKβ and modulates NF-κB signalling.Specific mutations in H5N1 mainly impact the magnitude and velocity of the host response in mice.Overlapping signals for translational regulation and packaging of influenza A virus segment 2Sensing of immature particles produced by dengue virus infected cells induces an antiviral response by plasmacytoid dendritic cells.The ubiquitination of the influenza A virus PB1-F2 protein is crucial for its biological functionEmergence of Highly Pathogenic Avian Influenza A(H5N1) Virus PB1-F2 Variants and Their Virulence in BALB/c Mice.Temperature-Sensitive Mutants in the Influenza A Virus RNA Polymerase: Alterations in the PA Linker Reduce Nuclear Targeting of the PB1-PA Dimer and Result in Viral AttenuationNaturally occurring swine influenza A virus PB1-F2 phenotypes that contribute to superinfection with Gram-positive respiratory pathogensThe Influenza Virus Protein PB1-F2 Increases Viral Pathogenesis through Neutrophil Recruitment and NK Cells Inhibition.Strain-dependent effects of PB1-F2 of triple-reassortant H3N2 influenza viruses in swine.Identification of one novel candidate probiotic Lactobacillus plantarum strain active against influenza virus infection in mice by a large-scale screening.Codon Deletions in the Influenza A Virus PA Gene Generate Temperature-Sensitive Viruses.TRIM22 inhibits influenza A virus infection by targeting the viral nucleoprotein for degradation.A novel cytotoxic sequence contributes to influenza A viral protein PB1-F2 pathogenicity and predisposition to secondary bacterial infection.Apoptosis signaling in influenza virus propagation, innate host defense, and lung injury.Host Response Comparison of H1N1- and H5N1-Infected Mice Identifies Two Potential Death Mechanisms.Transcriptomic profiling of a chicken lung epithelial cell line (CLEC213) reveals a mitochondrial respiratory chain activity boost during influenza virus infection.Amyloid Assemblies of Influenza A Virus PB1-F2 Protein Damage Membrane and Induce Cytotoxicity.An unbiased genetic screen reveals the polygenic nature of the influenza virus anti-interferon response.H5N1 influenza virulence, pathogenicity and transmissibility: what do we know?PB1-F2 modulates early host responses but does not affect the pathogenesis of H1N1 seasonal influenza virus.The influenza virus PB1-F2 protein has interferon antagonistic activity.Effects of PB1-F2 on the pathogenicity of H1N1 swine influenza virus in mice and pigs.Influenza A virus PB1-F2 protein prolongs viral shedding in chickens lengthening the transmission window.
P2860
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P2860
Influenza A virus protein PB1-F2 exacerbates IFN-beta expression of human respiratory epithelial cells.
description
2010 nî lūn-bûn
@nan
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
2010年论文
@zh
2010年论文
@zh-cn
name
Influenza A virus protein PB1- ...... respiratory epithelial cells.
@en
Influenza A virus protein PB1- ...... respiratory epithelial cells.
@nl
type
label
Influenza A virus protein PB1- ...... respiratory epithelial cells.
@en
Influenza A virus protein PB1- ...... respiratory epithelial cells.
@nl
prefLabel
Influenza A virus protein PB1- ...... respiratory epithelial cells.
@en
Influenza A virus protein PB1- ...... respiratory epithelial cells.
@nl
P2093
P50
P356
P1476
Influenza A virus protein PB1- ...... n respiratory epithelial cells
@en
P2093
Bernard Delmas
Bruno Da Costa
Christiane Bourdieu
Edwige Bouguyon
Laure Decamps
Sophie Dhorne-Pollet
P304
P356
10.4049/JIMMUNOL.0903952
P407
P577
2010-09-15T00:00:00Z