Nuclear phospho-Akt increase predicts synergy of PI3K inhibition and doxorubicin in breast and ovarian cancer.
about
Finding a better drug for epilepsy: the mTOR pathway as an antiepileptogenic targetThe phosphoinositide 3-kinase pathway and therapy resistance in cancerOct4 interaction with Hmgb2 regulates Akt signaling and pluripotencyThe determinants of head and neck cancer: Unmasking the PI3K pathway mutationsThe wedelolactone derivative inhibits estrogen receptor-mediated breast, endometrial, and ovarian cancer cells growthPI3K and mTOR signaling pathways in cancer: new data on targeted therapies.Akt: a double-edged sword in cell proliferation and genome stability.A novel oncolytic herpes simplex virus that synergizes with phosphoinositide 3-kinase/Akt pathway inhibitors to target glioblastoma stem cells.Inhibition of mitochondrial translation as a therapeutic strategy for human acute myeloid leukemia.DNA-PK mediates AKT activation and apoptosis inhibition in clinically acquired platinum resistance.MERIT40 Is an Akt Substrate that Promotes Resolution of DNA Damage Induced by Chemotherapy.Mutations in the phosphatidylinositol 3-kinase pathway: role in tumor progression and therapeutic implications in breast cancer.Role of phosphatidylinositol-3-kinase pathway in head and neck squamous cell carcinoma.Targeted Inhibition of Phosphoinositide 3-Kinase/Mammalian Target of Rapamycin Sensitizes Pancreatic Cancer Cells to Doxorubicin without Exacerbating Cardiac ToxicityPIK3CA dependence and sensitivity to therapeutic targeting in urothelial carcinoma.Targeting a common collaborator in cancer development.Lentiviral vector PLV-PI3KCG gene transfer inhibits hypoxic cardiomyocytes apoptosis.PI3K and Akt as molecular targets for cancer therapy: current clinical outcomes.The emergence of targeted drugs in breast cancer to prevent resistance to endocrine treatment and chemotherapy.Systems analysis of apoptotic priming in ovarian cancer identifies vulnerabilities and predictors of drug response.Curcumin induced apoptosis via PI3K/Akt-signalling pathways in SKOV3 cells.Activation of Akt characterizes estrogen receptor positive human breast cancers which respond to anthracyclines.High PTEN gene expression is a negative prognostic marker in human primary breast cancers with preserved p53 function.Shifting the balance of mitochondrial apoptosis: therapeutic perspectives.Tracing cancer networks with phosphoproteomics.
P2860
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P2860
Nuclear phospho-Akt increase predicts synergy of PI3K inhibition and doxorubicin in breast and ovarian cancer.
description
2010 nî lūn-bûn
@nan
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
2010年论文
@zh
2010年论文
@zh-cn
name
Nuclear phospho-Akt increase p ...... in breast and ovarian cancer.
@en
Nuclear phospho-Akt increase p ...... in breast and ovarian cancer.
@nl
type
label
Nuclear phospho-Akt increase p ...... in breast and ovarian cancer.
@en
Nuclear phospho-Akt increase p ...... in breast and ovarian cancer.
@nl
prefLabel
Nuclear phospho-Akt increase p ...... in breast and ovarian cancer.
@en
Nuclear phospho-Akt increase p ...... in breast and ovarian cancer.
@nl
P2093
P2860
P1476
Nuclear phospho-Akt increase p ...... in breast and ovarian cancer.
@en
P2093
Deepak Sampath
Jeffrey J Wallin
Kyle A Edgar
Lori S Friedman
Marcia Belvin
Robert Kassees
Wei Wei Prior
P2860
P304
P356
10.1126/SCITRANSLMED.3000630
P407
P577
2010-09-01T00:00:00Z