Inhibition of mitochondrial translation as a therapeutic strategy for human acute myeloid leukemia.
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The Aryl Hydrocarbon Receptor Relays Metabolic Signals to Promote Cellular RegenerationMitochondria, cholesterol and cancer cell metabolismIntegration of Mitochondrial Targeting for Molecular Cancer TherapeuticsBreast Cancer Metabolism and Mitochondrial Activity: The Possibility of Chemoprevention with MetforminMitochondrial targets for pharmacological intervention in human diseaseMitohormesisThe mitochondrial unfolded protein response in mammalian physiologyConcise review: Leukemia stem cells in personalized medicineTargeting mitochondria metabolism for cancer therapyROS homeostasis and metabolism: a dangerous liason in cancer cellsThe Antibiotic Drug Tigecycline: A Focus on its Promising Anticancer PropertiesCancer stem cell metabolism: a potential target for cancer therapyStructure of the large ribosomal subunit from human mitochondria.Metabolic adaptation to chronic inhibition of mitochondrial protein synthesis in acute myeloid leukemia cellsA novel formulation of tigecycline has enhanced stability and sustained antibacterial and antileukemic activityA Phase 1 study of intravenous infusions of tigecycline in patients with acute myeloid leukemiaAssociation of a cytarabine chemosensitivity related gene expression signature with survival in cytogenetically normal acute myeloid leukemia.Selective Vulnerability of Cancer Cells by Inhibition of Ca(2+) Transfer from Endoplasmic Reticulum to MitochondriaStructure-function insights reveal the human ribosome as a cancer target for antibiotics.Molecular pathways: BRAF induces bioenergetic adaptation by attenuating oxidative phosphorylation.Functional toxicology: tools to advance the future of toxicity testing.Inhibition of ATPIF1 ameliorates severe mitochondrial respiratory chain dysfunction in mammalian cells.Lysosomal disruption preferentially targets acute myeloid leukemia cells and progenitors.Mapping the cellular response to small molecules using chemogenomic fitness signatures.Doxycycline inhibits proliferation and induces apoptosis of both human papillomavirus positive and negative cervical cancer cell lines.Miniature short hairpin RNA screens to characterize antiproliferative drugsA genome-wide screen identifies yeast genes required for tolerance to technical toxaphene, an organochlorinated pesticide mixtureTyrosine kinase inhibition in leukemia induces an altered metabolic state sensitive to mitochondrial perturbations.AML cells have low spare reserve capacity in their respiratory chain that renders them susceptible to oxidative metabolic stressOncogene ablation-resistant pancreatic cancer cells depend on mitochondrial function.Isocitrate dehydrogenase 1 and 2 mutations induce BCL-2 dependence in acute myeloid leukemia.Select microtubule inhibitors increase lysosome acidity and promote lysosomal disruption in acute myeloid leukemia (AML) cells.Inhibition of the Mitochondrial Protease ClpP as a Therapeutic Strategy for Human Acute Myeloid Leukemia.Is cancer a metabolic rebellion against host aging? In the quest for immortality, tumor cells try to save themselves by boosting mitochondrial metabolismTargeting Mitochondrial Function to Treat Quiescent Tumor Cells in Solid TumorsTargeting glutaminolysis has antileukemic activity in acute myeloid leukemia and synergizes with BCL-2 inhibitionHigh mitochondrial mass identifies a sub-population of stem-like cancer cells that are chemo-resistant.Pyrvinium selectively targets blast phase-chronic myeloid leukemia through inhibition of mitochondrial respirationMitochondria "fuel" breast cancer metabolism: fifteen markers of mitochondrial biogenesis label epithelial cancer cells, but are excluded from adjacent stromal cellsMitochondrial dysfunction in breast cancer cells prevents tumor growth: understanding chemoprevention with metformin.
P2860
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P2860
Inhibition of mitochondrial translation as a therapeutic strategy for human acute myeloid leukemia.
description
2011 nî lūn-bûn
@nan
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
2011年论文
@zh
2011年论文
@zh-cn
name
Inhibition of mitochondrial tr ...... human acute myeloid leukemia.
@ast
Inhibition of mitochondrial tr ...... human acute myeloid leukemia.
@en
type
label
Inhibition of mitochondrial tr ...... human acute myeloid leukemia.
@ast
Inhibition of mitochondrial tr ...... human acute myeloid leukemia.
@en
prefLabel
Inhibition of mitochondrial tr ...... human acute myeloid leukemia.
@ast
Inhibition of mitochondrial tr ...... human acute myeloid leukemia.
@en
P2093
P2860
P50
P1433
P1476
Inhibition of mitochondrial tr ...... human acute myeloid leukemia.
@en
P2093
Angela C Rutledge
Bozhena Jhas
Brian H Robinson
Connie J Eaves
Courteney K Lai
Guri Giaever
Jason Moffat
Jean C Y Wang
Jeffery Wrana
Jessie H Cameron
P2860
P304
P356
10.1016/J.CCR.2011.10.015
P577
2011-11-01T00:00:00Z