about
Human ATP-binding cassette (ABC) transporter familyCannabis and tobacco smoke are not equally carcinogenic.Involvement of alpha-PAK-interacting exchange factor in the PAK1-c-Jun NH(2)-terminal kinase 1 activation and apoptosis induced by benzo[a]pyreneIdentification of genetically high risk individuals to lung cancer by DNA polymorphisms of the cytochrome P450IA1 geneRole of steroid 11 beta-hydroxylase and steroid 18-hydroxylase in the biosynthesis of glucocorticoids and mineralocorticoids in humansThe human orphan nuclear receptor PXR is activated by compounds that regulate CYP3A4 gene expression and cause drug interactionsIn vitro analysis of Ah receptor domains involved in ligand-activated DNA recognitionCloning of the Ah-receptor cDNA reveals a distinctive ligand-activated transcription factorAlternative splicing in the human cytochrome P450IIB6 gene generates a high level of aberrant messagesClose linkage of the human cytochrome P450IIA and P450IIB gene subfamilies: implications for the assignment of substrate specificityA Cytochrome P-450 Monooxygenase Catalyzes the First Step in the Conversion of Tabersonine to Vindoline in Catharanthus roseusBiochemical and genetic characterization of 2-carboxybenzaldehyde dehydrogenase, an enzyme involved in phenanthrene degradation by Nocardioides sp. strain KP7Human CYP1A1 gene: cosegregation of the enzyme inducibility phenotype and an RFLPGreen fluorescent protein (GFP) as a marker of aryl hydrocarbon receptor (AhR) function in developing zebrafish (Danio rerio).Comparative analysis of P450 signature motifs EXXR and CXG in the large and diverse kingdom of fungi: identification of evolutionarily conserved amino acid patterns characteristic of P450 familyCrystal structure of a thermophilic cytochrome P450 from the archaeon Sulfolobus solfataricusDifferential recruitment of coactivator RIP140 by Ah and estrogen receptors. Absence of a role for LXXLL motifsA self-sufficient cytochrome p450 with a primary structural organization that includes a flavin domain and a [2Fe-2S] redox centerThe expression of cytochrome P450 enzymes in human breast tumours and normal breast tissueMolecular cloning of cDNA for vitamin D3 25-hydroxylase from rat liver mitochondriaEffect of phenobarbital and 3-methylcholanthrene on the early oxidative stress component induced by lindane in rat liverPrimary structure of xylene monooxygenase: similarities to and differences from the alkane hydroxylation systemIntroduction of cytochrome P450IA2 metabolic capability into cell lines genetically matched for DNA repair proficiency/deficiencyMarked increases in hepatic NAD(P)H:oxidoreductase gene transcription and mRNA levels correlated with a mouse chromosome 7 deletionRegulation of mouse CYP1A1 gene expression by dioxin: requirement of two cis-acting elements during inductionDioxin-dependent activation of murine Cyp1a-1 gene transcription requires protein kinase C-dependent phosphorylationInducible, receptor-dependent protein-DNA interactions at a dioxin-responsive transcriptional enhancerIdentification of a cytochrome P450 gene by reverse transcription--PCR using degenerate primers containing inosineDioxin activates HIV-1 gene expression by an oxidative stress pathway requiring a functional cytochrome P450 CYP1A1 enzymeIn vitro anti-Mycobacterium avium activities of quinolones: predicted active structures and mechanistic considerationsNo association of vitamin D metabolism-related polymorphisms and melanoma risk as well as melanoma prognosis: a case-control studyHow are children different from adults?Effects of benzo(a)pyrene on intra-testicular function in F-344 ratsMetabolites of an Epac-selective cAMP analog induce cortisol synthesis by adrenocortical cells through a cAMP-independent pathwayEcologically appropriate xenobiotics induce cytochrome P450s in Apis melliferaCyp1a2(-/-) null mutant mice develop normally but show deficient drug metabolismDetection of CYP2C19 Genetic Variants in Malaysian Orang Asli from Massively Parallel Sequencing DataSequence of a novel cytochrome CYP2B cDNA coding for a protein which is expressed in a sebaceous gland, but not in the liverCloning and expression of rat 25-hydroxyvitamin D3-1alpha-hydroxylase cDNAMetabolic inactivation of retinoic acid by a novel P450 differentially expressed in developing mouse embryos
P2860
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P2860
description
1987 nî lūn-bûn
@nan
1987年の論文
@ja
1987年論文
@yue
1987年論文
@zh-hant
1987年論文
@zh-hk
1987年論文
@zh-mo
1987年論文
@zh-tw
1987年论文
@wuu
1987年论文
@zh
1987年论文
@zh-cn
name
P450 genes: structure, evolution, and regulation.
@en
P450 genes: structure, evolution, and regulation.
@nl
type
label
P450 genes: structure, evolution, and regulation.
@en
P450 genes: structure, evolution, and regulation.
@nl
prefLabel
P450 genes: structure, evolution, and regulation.
@en
P450 genes: structure, evolution, and regulation.
@nl
P1476
P450 genes: structure, evolution, and regulation.
@en
P2093
Gonzalez FJ
P304
P356
10.1146/ANNUREV.BI.56.070187.004501
P577
1987-01-01T00:00:00Z