High-level expression and purification of Cys-loop ligand-gated ion channels in a tetracycline-inducible stable mammalian cell line: GABAA and serotonin receptors
about
Overexpression of membrane proteins in mammalian cells for structural studiesMapping general anesthetic binding site(s) in human α1β3 γ-aminobutyric acid type A receptors with [³H]TDBzl-etomidate, a photoreactive etomidate analoguePhotoaffinity Labeling of Pentameric Ligand-Gated Ion Channels: A Proteomic Approach to Identify Allosteric Modulator Binding Sites.Engineering cells to improve protein expression.Multiple propofol-binding sites in a γ-aminobutyric acid type A receptor (GABAAR) identified using a photoreactive propofol analog.Specificity of intersubunit general anesthetic-binding sites in the transmembrane domain of the human α1β3γ2 γ-aminobutyric acid type A (GABAA) receptor.Anesthetic sites and allosteric mechanisms of action on Cys-loop ligand-gated ion channels.MiRNA mimic screen for improved expression of functional neurotensin receptor from HEK293 cellsAn allosteric coagonist model for propofol effects on α1β2γ2L γ-aminobutyric acid type A receptors.Deep amino acid sequencing of native brain GABAA receptors using high-resolution mass spectrometryPositive and Negative Allosteric Modulation of an α1β3γ2 γ-Aminobutyric Acid Type A (GABAA) Receptor by Binding to a Site in the Transmembrane Domain at the γ+-β- Interface.p-(4-Azipentyl)propofol: a potent photoreactive general anesthetic derivative of propofol.The pyrrole etomidate analog carboetomidate potently inhibits human 5-HT3A receptor function: comparisons with etomidate and potential implications for emetogenesisAllyl m-trifluoromethyldiazirine mephobarbital: an unusually potent enantioselective and photoreactive barbiturate general anesthetic.Human α1β3γ2L gamma-aminobutyric acid type A receptors: High-level production and purification in a functional state.Structural models of ligand-gated ion channels: sites of action for anesthetics and ethanol.Expression, Biochemistry, and Stabilization with Camel Antibodies of Membrane Proteins: Case Study of the Mouse 5-HT3 Receptor.Mapping General Anesthetic Sites in Heteromeric γ-Aminobutyric Acid Type A Receptors Reveals a Potential For Targeting Receptor Subtypes.Competitive Antagonism of Anesthetic Action at the γ-Aminobutyric Acid Type A Receptor by a Novel Etomidate Analog with Low Intrinsic Efficacy.High-level production and purification in a functional state of an extrasynaptic gamma-aminobutyric acid type A receptor containing α4β3δ subunits.Overexpression of granulocyte macrophage colony stimulating factor in breast cancer cells leads towards drug sensitization.
P2860
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P2860
High-level expression and purification of Cys-loop ligand-gated ion channels in a tetracycline-inducible stable mammalian cell line: GABAA and serotonin receptors
description
2010 nî lūn-bûn
@nan
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
2010年论文
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2010年论文
@zh-cn
name
High-level expression and puri ...... GABAA and serotonin receptors
@en
High-level expression and puri ...... GABAA and serotonin receptors.
@nl
type
label
High-level expression and puri ...... GABAA and serotonin receptors
@en
High-level expression and puri ...... GABAA and serotonin receptors.
@nl
prefLabel
High-level expression and puri ...... GABAA and serotonin receptors
@en
High-level expression and puri ...... GABAA and serotonin receptors.
@nl
P2093
P2860
P356
P1433
P1476
High-level expression and puri ...... GABAA and serotonin receptors
@en
P2093
Aiping Liu
Eileen S Krenzel
Enrique Arevalo
Innocent H Yamodo
Keith W Miller
Paul A Davies
Paula L Feinberg-Zadek
Rooma Desai
Sarah L Farmer
Stuart A Forman
P2860
P304
P356
10.1002/PRO.456
P577
2010-09-01T00:00:00Z