Importin subunit alpha-2 is identified as a potential biomarker for non-small cell lung cancer by integration of the cancer cell secretome and tissue transcriptome.
about
Regulation of nucleocytoplasmic transport in skeletal muscle.Prognostic value of increased KPNA2 expression in some solid tumors: A systematic review and meta-analysisKH domain protein RCF3 is a tissue-biased regulator of the plant miRNA biogenesis cofactor HYL1Overexpression of Kpnβ1 and Kpnα2 importin proteins in cancer derives from deregulated E2F activityKaryopherin alpha 2 expression is a novel diagnostic and prognostic factor for colorectal cancerOverexpression of karyopherin 2 in human ovarian malignant germ cell tumor correlates with poor prognosis.Targeting of DNA Damage Signaling Pathway Induced Senescence and Reduced Migration of Cancer cells.Molecular profiling of multiple human cancers defines an inflammatory cancer-associated molecular pattern and uncovers KPNA2 as a uniform poor prognostic cancer markerKaryopherin alpha2 is essential for rRNA transcription and protein synthesis in proliferative keratinocytesDistinct roles for classical nuclear import receptors in the growth of multinucleated muscle cells.Diversification of importin-α isoforms in cellular trafficking and disease statesHigh expression of KPNA2 defines poor prognosis in patients with upper tract urothelial carcinoma treated with radical nephroureterectomy.Targeting nuclear transporters in cancer: Diagnostic, prognostic and therapeutic potential.Nuclear importin α and its physiological importanceGlobal secretome analysis identifies novel mediators of bone metastasis.Development of a pipeline for automated, high-throughput analysis of paraspeckle proteins reveals specific roles for importin α proteins.Karyopherin alpha 2 is a novel prognostic marker and a potential therapeutic target for colon cancerQuantitative proteomics reveals regulation of karyopherin subunit alpha-2 (KPNA2) and its potential novel cargo proteins in nonsmall cell lung cancer.MiR-26b/KPNA2 axis inhibits epithelial ovarian carcinoma proliferation and metastasis through downregulating OCT4.Cell surface localization of importin α1/KPNA2 affects cancer cell proliferation by regulating FGF1 signalling.Nuclear size is sensitive to NTF2 protein levels in a manner dependent on Ran bindingIdentification and Characterization of Potential Biomarkers by Quantitative Tissue Proteomics of Primary Lung Adenocarcinoma.KPNA2 promotes cell proliferation and tumorigenicity in epithelial ovarian carcinoma through upregulation of c-Myc and downregulation of FOXO3a.mTOR regulates proteasomal degradation and Dp1/E2F1- mediated transcription of KPNA2 in lung cancer cellsDownregulation of KPNA2 in non-small-cell lung cancer is associated with Oct4 expressionMicroRNA-26b inhibits tumor metastasis by targeting the KPNA2/c-jun pathway in human gastric cancerProteomic profiling of the cancer cell secretome: informing clinical research.KPNA2 is overexpressed in human and mouse endometrial cancers and promotes cellular proliferation.Nuclear karyopherin-α2 expression in primary lesions and metastatic lymph nodes was associated with poor prognosis and progression in gastric cancer.Combined proteome and transcriptome analyses for the discovery of urinary biomarkers for urothelial carcinoma.Mass spectrometry-based proteomics in molecular diagnostics: discovery of cancer biomarkers using tissue culture.Nuclear transport receptor karyopherin-α2 promotes malignant breast cancer phenotypes in vitro.Silencing of karyopherin α2 inhibits cell growth and survival in human hepatocellular carcinomaOverexpression of karyopherin-α2 in cholangiocarcinoma correlates with poor prognosis and gemcitabine sensitivity via nuclear translocation of DNA repair proteins.High nuclear karyopherin α 2 expression is a strong and independent predictor of biochemical recurrence in prostate cancer patients treated by radical prostatectomy.KPNA2 promotes migration and invasion in epithelial ovarian cancer cells by inducing epithelial-mesenchymal transition via Akt/GSK-3β/Snail activation.Nuclear karyopherin a2: a novel biomarker for infiltrative astrocytomas.KPNA2 is a potential diagnostic serum biomarker for epithelial ovarian cancer and correlates with poor prognosis.Karyopherins in cancer.High expression of karyopherin-α2 and stathmin 1 is associated with proliferation potency and transformation in the bile duct and gall bladder epithelia in the cases of pancreaticobiliary maljunction.
P2860
Q27693239-7BBDDF4D-D47D-4F00-8113-CA1D62E24561Q28071479-A1ED70DA-05C4-4CC5-95DE-97F7E9ADA94CQ28607201-DCD7AE6B-E7D5-4496-B01C-72A022866C75Q28742539-EFE44965-9D84-4EC7-8617-22F88E153C52Q33598264-21596B9F-F7BD-4B8E-9CFB-BE4CBA6292BDQ34409715-578C043B-9D32-4093-BB0B-63A128CA8AB5Q34416018-C1BCC973-79AB-4DE9-9572-3C5C336E9BEDQ34639059-284662C4-9ACF-4F27-A1E1-AB4E515E5365Q35009420-D9D05BFB-FE74-4D41-B6E7-E63398F926E5Q35165205-6B637914-CA2A-4E9E-8E2A-59F9AC873765Q35511186-70B07282-D098-429F-9BCC-52C77F3914A7Q35609624-F1BB7D5B-92EF-4C5F-9F3F-5747811CBD44Q35955008-D200C4BB-9EE7-4557-86FE-5A3123BA48C2Q36034989-E84FD69C-7428-46E7-A9BC-B6959ED83CCDQ36210409-E0724262-882E-44CA-80DA-F94DE211C26CQ36291283-45017FD2-1B50-4B36-BC29-1642F3AF40D0Q36336250-BC5AD6B3-E510-4262-8E8A-E99984C59A19Q36386895-B15B6C50-21EB-4104-B4E2-604BECC84F24Q36414297-139A7D61-FA04-44B5-8C4D-C6816E90CE61Q36591378-80FF745E-AE52-45CF-A6E5-3A58953E7542Q36743893-A805A532-7771-4F97-ABCB-CF612E6C5C29Q37076896-C9DAB0DB-C3C9-4C76-B71B-C2A2F4EF2AB6Q37148209-16BECDE5-390E-422E-A016-ABE1016496E5Q37295372-F3FCBC38-33A4-43E1-B01B-B3F241DFF3D7Q37360952-FB2DF32D-2051-45ED-B65A-4D3AD6F9DA87Q37457579-9DAAED15-235C-4F1F-85FC-750FDCC439BAQ38659528-0C7DF2F0-C369-4C3A-A29D-98A24D115EBDQ38984603-74A4518A-3BA0-4586-94F4-E3E7C2E618BFQ39142005-11752306-98C2-4E0A-8CDC-9984AB06CB98Q39165376-C8B560DB-2904-4EE4-8CF0-8B77A0390202Q39468169-5DDB19A6-B46B-4E0B-B15E-87513DF5A80BQ39475921-8B353A8A-3D2E-43A8-B84C-7109DD6AB21BQ41055921-F4978F2F-B42D-4F3C-B3F1-C333D634922EQ41091924-283E57AA-3593-41EF-A84A-1289C002F86EQ43848815-830FDB6C-2249-4DFB-8DC3-FFC88DE8D8C5Q47101812-B343F4AA-A738-4CE3-B0A0-C23B0E8D4896Q48448124-0CED3004-A294-49CF-8CA8-2A649B268801Q48628148-225053BB-DA1A-4B48-93D6-07BFA0A5C0D4Q50134836-6C7FAA95-8C2C-4888-A08B-F0BCC51350FBQ51685400-60E62579-F122-4DF4-87AB-F8ED4E321AA9
P2860
Importin subunit alpha-2 is identified as a potential biomarker for non-small cell lung cancer by integration of the cancer cell secretome and tissue transcriptome.
description
2011 nî lūn-bûn
@nan
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
2011年论文
@zh
2011年论文
@zh-cn
name
Importin subunit alpha-2 is id ...... tome and tissue transcriptome.
@en
Importin subunit alpha-2 is id ...... tome and tissue transcriptome.
@nl
type
label
Importin subunit alpha-2 is id ...... tome and tissue transcriptome.
@en
Importin subunit alpha-2 is id ...... tome and tissue transcriptome.
@nl
prefLabel
Importin subunit alpha-2 is id ...... tome and tissue transcriptome.
@en
Importin subunit alpha-2 is id ...... tome and tissue transcriptome.
@nl
P2093
P2860
P50
P356
P1476
Importin subunit alpha-2 is id ...... tome and tissue transcriptome.
@en
P2093
Chi-De Chen
Chih-Liang Wang
Chih-Wei Wang
Chun-I Wang
Ying Liang
Ying-Huang Tsai
Yu-Sun Chang
P2860
P304
P356
10.1002/IJC.25568
P577
2011-05-01T00:00:00Z