The retinoblastoma protein binds the promoter of the survival gene bcl-2 and regulates its transcription in epithelial cells through transcription factor AP-2.
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BCL-2 is a downstream target of ATF5 that mediates the prosurvival function of ATF5 in a cell type-dependent mannerAP2 transcription factor induces apoptosis in retinoblastoma cellsFunctional interactions between the estrogen receptor coactivator PELP1/MNAR and retinoblastoma proteinGAS41 interacts with transcription factor AP-2beta and stimulates AP-2beta-mediated transactivationActivator protein 2alpha associates with adenomatous polyposis coli/beta-catenin and Inhibits beta-catenin/T-cell factor transcriptional activity in colorectal cancer cellsDisruptive environmental chemicals and cellular mechanisms that confer resistance to cell deathCell autonomous roles for AP-2alpha in lens vesicle separation and maintenance of the lens epithelial cell phenotypeTranscription profiling of lung adenocarcinomas of c-myc-transgenic mice: identification of the c-myc regulatory gene network.Yin Yang 1 cooperates with activator protein 2 to stimulate ERBB2 gene expression in mammary cancer cells.Two regions within the proximal steroidogenic factor 1 promoter drive somatic cell-specific activity in developing gonads of the female mouse.Requirement of clathrin heavy chain for p53-mediated transcription.Aberrant expressions of AP-2α splice variants in pancreatic cancerUrokinase-type plasminogen activator receptor (uPAR)-mediated regulation of WNT/β-catenin signaling is enhanced in irradiated medulloblastoma cells.Activator protein-2 in carcinogenesis with a special reference to breast cancer--a mini review.Mutations in the SOD2 promoter reveal a molecular basis for an activating protein 2-dependent dysregulation of manganese superoxide dismutase expression in cancer cellsExpression of integrin alpha 10 is transcriptionally activated by pRb in mouse osteoblasts and is downregulated in multiple solid tumorsRoles of AP-2 transcription factors in the regulation of cartilage and skeletal development.Signaling and mechanical roles of E-cadherin.A transcriptional regulatory element in the coding sequence of the human Bcl-2 gene.Ursodeoxycholic acid modulates E2F-1 and p53 expression through a caspase-independent mechanism in transforming growth factor beta1-induced apoptosis of rat hepatocytes.The natural diterpene ent-16β-17α-dihydroxykaurane down-regulates Bcl-2 by disruption of the Ap-2α/Rb transcription activating complex and induces E2F1 up-regulation in MCF-7 cells.Genome-wide analysis of transcription factor E2F1 mutant proteins reveals that N- and C-terminal protein interaction domains do not participate in targeting E2F1 to the human genome.Caveolin-1 tyrosine phosphorylation enhances paclitaxel-mediated cytotoxicity.Investigation of the miR16-1 (C > T) + 7 Substitution in Seven Different Types of Cancer from Three Ethnic Groups.Retinoblastoma protein acts as Pax 8 transcriptional coactivator.CHIP buffers heterogeneous Bcl-2 expression levels to prevent augmentation of anticancer drug-resistant cell population.The atypical mitogen-activated protein kinase ERK3 is essential for establishment of epithelial architecture.
P2860
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P2860
The retinoblastoma protein binds the promoter of the survival gene bcl-2 and regulates its transcription in epithelial cells through transcription factor AP-2.
description
2002 nî lūn-bûn
@nan
2002年の論文
@ja
2002年論文
@yue
2002年論文
@zh-hant
2002年論文
@zh-hk
2002年論文
@zh-mo
2002年論文
@zh-tw
2002年论文
@wuu
2002年论文
@zh
2002年论文
@zh-cn
name
The retinoblastoma protein bin ...... ugh transcription factor AP-2.
@en
The retinoblastoma protein bin ...... ugh transcription factor AP-2.
@nl
type
label
The retinoblastoma protein bin ...... ugh transcription factor AP-2.
@en
The retinoblastoma protein bin ...... ugh transcription factor AP-2.
@nl
prefLabel
The retinoblastoma protein bin ...... ugh transcription factor AP-2.
@en
The retinoblastoma protein bin ...... ugh transcription factor AP-2.
@nl
P2093
P2860
P1476
The retinoblastoma protein bin ...... ugh transcription factor AP-2.
@en
P2093
Chantal E Cremisi
Irina Naguibneva
John C Reed
Julien T Decesse
Stephanie Decary
P2860
P304
P356
10.1128/MCB.22.22.7877-7888.2002
P407
P577
2002-11-01T00:00:00Z